6EFK

Crystal structure of the human CHIP TPR domain in complex with a 5mer acetylated HSP70 peptide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000209	biological_process	protein polyubiquitination
A	0061630	molecular_function	ubiquitin protein ligase activity
B	0000209	biological_process	protein polyubiquitination
B	0061630	molecular_function	ubiquitin protein ligase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	5
Details	binding site for residue NA A 201

Chain	Residue
A	GLN32
A	ARG35
A	ARG128
A	HOH324
A	HOH424

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site_id	AC2
Number of Residues	10
Details	binding site for Di-peptide ACE C 636 and ILE C 637

Chain	Residue
B	PHE99
B	PHE131
B	ASP134
C	GLU638
C	GLU639
C	HOH706
A	ARG40
A	ARG153
B	LYS95
B	PHE98

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site_id	AC3
Number of Residues	9
Details	binding site for Di-peptide ACE D 636 and ILE D 637

Chain	Residue
A	LYS95
A	PHE98
A	PHE99
A	PHE131
A	ASP134
B	ARG40
D	GLU638
D	GLU639
D	HOH704

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	2
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:18669648, ECO:0007744|PubMed:21406692, ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER23
B	SER23

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site_id	SWS_FT_FI2
Number of Residues	4
Details	MOD_RES: Phosphoserine => ECO:0007744|PubMed:23186163

Chain	Residue	Details
A	SER25
A	SER149
B	SER25
B	SER149

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