Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000287 | molecular_function | magnesium ion binding |
| A | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004737 | molecular_function | pyruvate decarboxylase activity |
| A | 0005634 | cellular_component | nucleus |
| A | 0005829 | cellular_component | cytosol |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0030976 | molecular_function | thiamine pyrophosphate binding |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000287 | molecular_function | magnesium ion binding |
| B | 0000949 | biological_process | aromatic amino acid family catabolic process to alcohol via Ehrlich pathway |
| B | 0003824 | molecular_function | catalytic activity |
| B | 0004737 | molecular_function | pyruvate decarboxylase activity |
| B | 0005634 | cellular_component | nucleus |
| B | 0005829 | cellular_component | cytosol |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0030976 | molecular_function | thiamine pyrophosphate binding |
| B | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue PY0 A 601 |
| Chain | Residue |
| A | HIS92 |
| A | CYS221 |
| A | HIS225 |
| A | GLY286 |
| A | ALA287 |
| A | LEU288 |
| A | HIS310 |
| A | SER311 |
| site_id | AC2 |
| Number of Residues | 18 |
| Details | binding site for residue TPP A 602 |
| Chain | Residue |
| A | THR390 |
| A | GLY413 |
| A | ILE415 |
| A | GLY443 |
| A | ASP444 |
| A | GLY445 |
| A | SER446 |
| A | ASN471 |
| A | GLY473 |
| A | TYR474 |
| A | THR475 |
| A | ILE476 |
| A | GLU477 |
| A | MG603 |
| B | PRO26 |
| B | GLU51 |
| B | VAL76 |
| A | GLY389 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue MG A 603 |
| Chain | Residue |
| A | ASP444 |
| A | ASN471 |
| A | GLY473 |
| A | TPP602 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue 1PE A 604 |
| Chain | Residue |
| A | ASP121 |
| A | PHE122 |
| A | HIS126 |
| A | ARG127 |
| A | MET138 |
| site_id | AC5 |
| Number of Residues | 19 |
| Details | binding site for residue TPP B 601 |
| Chain | Residue |
| A | PRO26 |
| A | GLY27 |
| A | GLU51 |
| A | VAL76 |
| B | GLY389 |
| B | THR390 |
| B | GLY413 |
| B | ILE415 |
| B | GLY443 |
| B | ASP444 |
| B | GLY445 |
| B | SER446 |
| B | ASN471 |
| B | GLY473 |
| B | TYR474 |
| B | THR475 |
| B | ILE476 |
| B | GLU477 |
| B | MG602 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue MG B 602 |
| Chain | Residue |
| B | ASP444 |
| B | LEU469 |
| B | ASN471 |
| B | GLY473 |
| B | TPP601 |
Functional Information from PROSITE/UniProt
| site_id | PS00187 |
| Number of Residues | 20 |
| Details | TPP_ENZYMES Thiamine pyrophosphate enzymes signature. FAaeeidPkkrvIlFiGDGS |
| Chain | Residue | Details |
| A | PHE427-SER446 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | ASP28 | |
| B | ASP28 | |
| B | HIS115 | |
| B | THR390 | |
| B | GLY413 | |
| B | ASP444 | |
| B | GLY445 | |
| B | ASN471 | |
| B | GLY473 | |
| B | GLU477 | |
| A | HIS115 | |
| A | THR390 | |
| A | GLY413 | |
| A | ASP444 | |
| A | GLY445 | |
| A | ASN471 | |
| A | GLY473 | |
| A | GLU477 | |
