6EBZ
Crystal Structure of the Class Ie Ribonucleotide Reductase Beta Subunit from Aerococcus urinae in Activated Form with Thiocyanate Bound
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
A | 0005829 | cellular_component | cytosol |
A | 0005971 | cellular_component | ribonucleoside-diphosphate reductase complex |
A | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
A | 0016020 | cellular_component | membrane |
A | 0016491 | molecular_function | oxidoreductase activity |
A | 0046872 | molecular_function | metal ion binding |
B | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
B | 0005829 | cellular_component | cytosol |
B | 0005971 | cellular_component | ribonucleoside-diphosphate reductase complex |
B | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
B | 0016020 | cellular_component | membrane |
B | 0016491 | molecular_function | oxidoreductase activity |
B | 0046872 | molecular_function | metal ion binding |
C | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
C | 0005829 | cellular_component | cytosol |
C | 0005971 | cellular_component | ribonucleoside-diphosphate reductase complex |
C | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
C | 0016020 | cellular_component | membrane |
C | 0016491 | molecular_function | oxidoreductase activity |
C | 0046872 | molecular_function | metal ion binding |
D | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
D | 0005829 | cellular_component | cytosol |
D | 0005971 | cellular_component | ribonucleoside-diphosphate reductase complex |
D | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
D | 0016020 | cellular_component | membrane |
D | 0016491 | molecular_function | oxidoreductase activity |
D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 5 |
Details | binding site for residue CA A 401 |
Chain | Residue |
A | GLY263 |
A | GLU267 |
A | HOH623 |
B | GLY261 |
B | HOH639 |
site_id | AC2 |
Number of Residues | 7 |
Details | binding site for residue GOL A 402 |
Chain | Residue |
B | LEU264 |
B | ALA265 |
B | HOH612 |
A | ASP260 |
B | HIS256 |
B | TYR259 |
B | ASP260 |
site_id | AC3 |
Number of Residues | 1 |
Details | binding site for residue SCN B 401 |
Chain | Residue |
B | PHE241 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue SCN B 402 |
Chain | Residue |
B | LEU84 |
B | ASP85 |
B | GLN88 |
B | MET175 |
B | PRO176 |
B | LEU180 |
B | LYS210 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue SCN B 403 |
Chain | Residue |
A | GLU137 |
B | TYR5 |
B | ASN28 |
B | LYS31 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue CA B 404 |
Chain | Residue |
B | SER128 |
B | HOH551 |
B | HOH582 |
B | HOH585 |
B | HOH666 |
C | HOH545 |
C | HOH557 |
site_id | AC7 |
Number of Residues | 6 |
Details | binding site for residue CA B 405 |
Chain | Residue |
A | GLY261 |
A | HOH648 |
B | GLY263 |
B | GLU267 |
B | HOH591 |
B | HOH628 |
site_id | AC8 |
Number of Residues | 4 |
Details | binding site for residue GOL B 406 |
Chain | Residue |
B | ASP68 |
B | ASP69 |
C | LYS232 |
C | GLU235 |
site_id | AC9 |
Number of Residues | 2 |
Details | binding site for residue SCN C 401 |
Chain | Residue |
C | PHE241 |
C | HOH624 |
site_id | AD1 |
Number of Residues | 8 |
Details | binding site for residue SCN C 402 |
Chain | Residue |
C | ASP260 |
C | GLY263 |
C | ALA265 |
C | ASP266 |
C | GLU267 |
C | CA404 |
D | ASP260 |
D | GLY261 |
site_id | AD2 |
Number of Residues | 6 |
Details | binding site for residue CA C 403 |
Chain | Residue |
B | HOH560 |
B | HOH592 |
C | SER128 |
C | HOH561 |
C | HOH587 |
C | HOH648 |
site_id | AD3 |
Number of Residues | 6 |
Details | binding site for residue CA C 404 |
Chain | Residue |
C | GLY263 |
C | GLU267 |
C | SCN402 |
C | HOH601 |
D | GLY261 |
D | HOH620 |
site_id | AD4 |
Number of Residues | 6 |
Details | binding site for residue CA D 401 |
Chain | Residue |
C | GLY261 |
D | GLY263 |
D | ASP266 |
D | GLU267 |
D | HOH607 |
D | HOH621 |
site_id | AD5 |
Number of Residues | 15 |
Details | binding site for Ligand residues DAH A 123 through GLY A 124 bound to SER A 122 |
Chain | Residue |
A | PHE78 |
A | LEU81 |
A | THR82 |
A | ASP85 |
A | HIS119 |
A | ALA120 |
A | ARG121 |
A | SER122 |
A | THR125 |
A | ILE126 |
A | PHE127 |
A | SER128 |
A | PHE184 |
A | ILE206 |
B | ASN30 |
site_id | AD6 |
Number of Residues | 15 |
Details | binding site for Ligand residues DAH B 123 through GLY B 124 bound to SER B 122 |
Chain | Residue |
A | ASN30 |
B | LEU81 |
B | THR82 |
B | ASP85 |
B | HIS119 |
B | ALA120 |
B | ARG121 |
B | SER122 |
B | THR125 |
B | ILE126 |
B | PHE127 |
B | SER128 |
B | PHE184 |
B | HOH515 |
B | HOH558 |
site_id | AD7 |
Number of Residues | 15 |
Details | binding site for Ligand residues DAH C 123 through GLY C 124 bound to SER C 122 |
Chain | Residue |
C | LEU81 |
C | THR82 |
C | ASP85 |
C | HIS119 |
C | ALA120 |
C | ARG121 |
C | SER122 |
C | THR125 |
C | ILE126 |
C | PHE127 |
C | SER128 |
C | PHE184 |
C | ILE206 |
C | HOH501 |
D | ASN30 |
site_id | AD8 |
Number of Residues | 14 |
Details | binding site for Ligand DAH C 123 bound to SER C 122 |
Chain | Residue |
C | LEU81 |
C | THR82 |
C | ASP85 |
C | HIS119 |
C | ALA120 |
C | ARG121 |
C | SER122 |
C | GLY124 |
C | THR125 |
C | ILE126 |
C | PHE127 |
C | PHE184 |
C | ILE206 |
C | HOH501 |
site_id | AD9 |
Number of Residues | 15 |
Details | binding site for Ligand residues DAH D 123 through GLY D 124 bound to SER D 122 |
Chain | Residue |
C | ASN30 |
D | LEU81 |
D | THR82 |
D | ASP85 |
D | HIS119 |
D | ALA120 |
D | ARG121 |
D | SER122 |
D | THR125 |
D | ILE126 |
D | PHE127 |
D | SER128 |
D | PHE184 |
D | HOH501 |
D | HOH505 |