Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | PRO152 |
| A | ASP153 |
| A | VAL154 |
| A | LYS156 |
| A | HOH402 |
| A | HOH520 |
| A | HOH596 |
| A | HOH652 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | SER164 |
| A | ASP165 |
| A | HOH413 |
| A | HOH444 |
| A | HOH559 |
| A | HOH631 |
| A | ALA132 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | LYS169 |
| A | PRO173 |
| A | GLY174 |
| A | GLN240 |
| A | HOH482 |
| A | HOH552 |
| A | HOH556 |
| A | HOH604 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | ASN95 |
| A | THR98 |
| A | ASN100 |
| A | HOH422 |
| A | HOH511 |
| A | HOH563 |
| site_id | AC5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 305 |
| Chain | Residue |
| A | ILE47 |
| A | ASN48 |
| A | LYS239 |
| A | ILE242 |
| A | HOH430 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 306 |
| Chain | Residue |
| A | ASN95 |
| A | ASN97 |
| A | SER110 |
| A | HOH477 |
| A | HOH601 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue SO4 A 307 |
| Chain | Residue |
| A | CYS128 |
| A | ALA129 |
| A | SER130 |
| A | THR134 |
| A | SER202 |
| A | HOH409 |
| A | HOH411 |
| A | HOH418 |
| A | HOH435 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 308 |
| Chain | Residue |
| A | GLU70 |
| A | ASN72 |
| A | VAL75 |
| A | GLU80 |
| A | HOH429 |
| A | HOH531 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. DScqGDSGGPVV |
| Chain | Residue | Details |
| A | ASP189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | SITE: Reactive bond for trypsin => ECO:0000250 |
| Chain | Residue | Details |
| I | LYS3 | |
| A | ASP102 | |
| A | SER195 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU70 | |
| A | ASN72 | |
| A | VAL75 | |
| A | GLU80 | |
| A | ASP189 | |
| A | GLN192 | |
| A | SER195 | |
