6E86
Solution structure of ZZZ3 ZZ domain in complex with histone H3K4ac peptide
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0008270 | molecular_function | zinc ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ZN B 101 |
| Chain | Residue |
| B | CYS823 |
| B | CYS826 |
| B | ILE828 |
| B | CYS850 |
| B | CYS853 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue ZN B 102 |
| Chain | Residue |
| B | CYS838 |
| B | CYS841 |
| B | HIS863 |
| B | HIS867 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for Ligand residues ALY A 4 through GLN A 5 bound to THR A 3 |
| Chain | Residue |
| A | ARG2 |
| A | THR3 |
| A | THR6 |
| B | VAL819 |
| B | GLY820 |
Functional Information from PROSITE/UniProt
| site_id | PS01357 |
| Number of Residues | 31 |
| Details | ZF_ZZ_1 Zinc finger ZZ-type signature. CdnCgiepiqgvRWhCqdcppEmSLdFCdsC |
| Chain | Residue | Details |
| B | CYS823-CYS853 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | MOD_RES: Citrulline; alternate => ECO:0000269|PubMed:16567635 |
| Chain | Residue | Details |
| A | ARG2 | |
| B | CYS826 | |
| B | CYS838 | |
| B | CYS841 | |
| B | CYS850 | |
| B | CYS853 | |
| B | HIS863 | |
| B | HIS867 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by HASPIN and VRK1 => ECO:0000269|PubMed:15681610, ECO:0000269|PubMed:16185088, ECO:0000269|PubMed:31527692 |
| Chain | Residue | Details |
| A | THR3 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 1 |
| Details | MOD_RES: N6-methyllysine; alternate => ECO:0000269|PubMed:16267050, ECO:0000269|PubMed:16457588, ECO:0000269|PubMed:17194708 |
| Chain | Residue | Details |
| A | ALY4 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | MOD_RES: 5-glutamyl serotonin; alternate => ECO:0000269|PubMed:30867594 |
| Chain | Residue | Details |
| A | GLN5 |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | MOD_RES: Phosphothreonine; by PKC => ECO:0000269|PubMed:20228790 |
| Chain | Residue | Details |
| A | THR6 |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | MOD_RES: Symmetric dimethylarginine; by PRMT5; alternate => ECO:0000250|UniProtKB:P68433 |
| Chain | Residue | Details |
| A | ARG8 |
