6E66
Crystal structure of bacterial N-acetylglucosamine transferase NleB
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0016757 | molecular_function | glycosyltransferase activity |
| A | 0030145 | molecular_function | manganese ion binding |
| A | 0030430 | cellular_component | host cell cytoplasm |
| A | 0034054 | biological_process | symbiont-mediated suppression of host defense-related programmed cell death |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0085034 | biological_process | symbiont-mediated suppression of host NF-kappaB cascade |
| A | 0090729 | molecular_function | toxin activity |
| A | 0106362 | molecular_function | protein-arginine N-acetylglucosaminyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO A 401 |
| Chain | Residue |
| A | THR179 |
| A | GLY180 |
| A | ILE187 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 1 |
| Details | ACT_SITE: Proton acceptor => ECO:0000269|PubMed:30979585 |
| Chain | Residue | Details |
| A | CAS229 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 5 |
| Details | BINDING: BINDING => ECO:0000305|PubMed:30979585, ECO:0007744|PDB:6ACI |
| Chain | Residue | Details |
| A | GLN24 | |
| A | TYR48 | |
| A | TYR195 | |
| A | SER300 | |
| A | SER305 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:30979585, ECO:0007744|PDB:6ACI |
| Chain | Residue | Details |
| A | ASP199 | |
| A | ASN298 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 4 |
| Details | CARBOHYD: N-beta-linked (GlcNAc) arginine; by autocatalysis => ECO:0000269|PubMed:32432056 |
| Chain | Residue | Details |
| A | ARG-11 | |
| A | ARG29 | |
| A | ARG135 | |
| A | ARG269 |
