6E5R
Crystal structure of the apo domain-swapped dimer Q108K:T51D:A28C mutant of human Cellular Retinol Binding Protein II
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001523 | biological_process | retinoid metabolic process |
| A | 0005501 | molecular_function | retinoid binding |
| A | 0005504 | molecular_function | fatty acid binding |
| A | 0005634 | cellular_component | nucleus |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0005829 | cellular_component | cytosol |
| A | 0006776 | biological_process | vitamin A metabolic process |
| A | 0008289 | molecular_function | lipid binding |
| A | 0008544 | biological_process | epidermis development |
| A | 0015908 | biological_process | fatty acid transport |
| A | 0016918 | molecular_function | retinal binding |
| A | 0019841 | molecular_function | retinol binding |
| A | 0044325 | molecular_function | transmembrane transporter binding |
| A | 0098681 | cellular_component | synaptic ribbon |
| A | 0140104 | molecular_function | molecular carrier activity |
| A | 1904768 | molecular_function | all-trans-retinol binding |
| B | 0001523 | biological_process | retinoid metabolic process |
| B | 0005501 | molecular_function | retinoid binding |
| B | 0005504 | molecular_function | fatty acid binding |
| B | 0005634 | cellular_component | nucleus |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0005829 | cellular_component | cytosol |
| B | 0006776 | biological_process | vitamin A metabolic process |
| B | 0008289 | molecular_function | lipid binding |
| B | 0008544 | biological_process | epidermis development |
| B | 0015908 | biological_process | fatty acid transport |
| B | 0016918 | molecular_function | retinal binding |
| B | 0019841 | molecular_function | retinol binding |
| B | 0044325 | molecular_function | transmembrane transporter binding |
| B | 0098681 | cellular_component | synaptic ribbon |
| B | 0140104 | molecular_function | molecular carrier activity |
| B | 1904768 | molecular_function | all-trans-retinol binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 5 |
| Details | binding site for residue ACT A 201 |
| Chain | Residue |
| A | ARG2 |
| A | GLY46 |
| A | ASP47 |
| B | THR65 |
| B | TRP88 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue GOL A 202 |
| Chain | Residue |
| A | MET10 |
| A | ARG35 |
| A | LEU36 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 203 |
| Chain | Residue |
| A | VAL92 |
| A | ILE110 |
| A | GLU111 |
| B | THR1 |
| A | ASP91 |
| site_id | AC4 |
| Number of Residues | 2 |
| Details | binding site for residue GOL A 204 |
| Chain | Residue |
| A | ASP63 |
| A | TYR116 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue ACT B 201 |
| Chain | Residue |
| B | ASP71 |
| B | HIS81 |
| B | VAL92 |
| B | TRP109 |
| B | ILE110 |
| B | GLU111 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue ACT B 202 |
| Chain | Residue |
| B | CYS95 |
| B | GLY105 |
| B | THR120 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 203 |
| Chain | Residue |
| B | HIS81 |
| B | GLU89 |
| B | LYS107 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue GOL B 204 |
| Chain | Residue |
| A | ARG58 |
| A | TYR60 |
| B | GLN38 |
| B | THR53 |
Functional Information from PROSITE/UniProt
| site_id | PS00214 |
| Number of Residues | 18 |
| Details | FABP Cytosolic fatty-acid binding proteins signature. GTWeMesNeNFEgYMKAL |
| Chain | Residue | Details |
| A | GLY6-LEU23 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"18076076","evidenceCode":"ECO:0000269"}]} |
| Chain | Residue | Details |
