6E4V
The Crystal Structure of FhuE from E. coli in complex with its substrate Coprogen
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0006811 | biological_process | monoatomic ion transport |
| A | 0006826 | biological_process | iron ion transport |
| A | 0006879 | biological_process | intracellular iron ion homeostasis |
| A | 0009279 | cellular_component | cell outer membrane |
| A | 0015092 | molecular_function | high-affinity ferric iron transmembrane transporter activity |
| A | 0015343 | molecular_function | siderophore-iron transmembrane transporter activity |
| A | 0015344 | molecular_function | siderophore uptake transmembrane transporter activity |
| A | 0015687 | biological_process | ferric-hydroxamate import into cell |
| A | 0015891 | biological_process | siderophore transport |
| A | 0016020 | cellular_component | membrane |
| A | 0033214 | biological_process | siderophore-iron import into cell |
| A | 0034755 | biological_process | iron ion transmembrane transport |
| A | 0038023 | molecular_function | signaling receptor activity |
| A | 0042928 | biological_process | ferrichrome import into cell |
| A | 0044718 | biological_process | siderophore transmembrane transport |
| A | 0072711 | biological_process | cellular response to hydroxyurea |
Functional Information from PROSITE/UniProt
| site_id | PS01156 |
| Number of Residues | 18 |
| Details | TONB_DEPENDENT_REC_2 TonB-dependent receptor (TBDR) proteins signature 2. SivyGtPRnFsITGtYqF |
| Chain | Residue | Details |
| A | SER712-PHE729 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 109 |
| Details | Domain: {"description":"TBDR plug","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 540 |
| Details | Domain: {"description":"TBDR beta-barrel","evidences":[{"source":"PROSITE-ProRule","id":"PRU01360","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 17 |
| Details | Motif: {"description":"TonB C-terminal box"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 12 |
| Details | Compositional bias: {"description":"Polar residues","evidences":[{"source":"SAM","id":"MobiDB-lite","evidenceCode":"ECO:0000256"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 6 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"31098021","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6E4V","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
