6E2Y
MDDEF in complex with MVAPP, ADP, sulfate and cobalt. Anomalous data
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004163 | molecular_function | diphosphomevalonate decarboxylase activity |
A | 0005524 | molecular_function | ATP binding |
A | 0005829 | cellular_component | cytosol |
A | 0006629 | biological_process | lipid metabolic process |
A | 0008299 | biological_process | isoprenoid biosynthetic process |
A | 0016301 | molecular_function | kinase activity |
A | 0016310 | biological_process | phosphorylation |
A | 0016829 | molecular_function | lyase activity |
A | 0016831 | molecular_function | carboxy-lyase activity |
A | 0019287 | biological_process | isopentenyl diphosphate biosynthetic process, mevalonate pathway |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 11 |
Details | binding site for residue SO4 A 401 |
Chain | Residue |
A | GLY102 |
A | CO405 |
A | HOH518 |
A | LEU103 |
A | ALA104 |
A | SER191 |
A | ASP282 |
A | ALA283 |
A | ADP402 |
A | DP6403 |
A | CO404 |
site_id | AC2 |
Number of Residues | 21 |
Details | binding site for residue ADP A 402 |
Chain | Residue |
A | PHE57 |
A | VAL72 |
A | SER93 |
A | ASN95 |
A | ALA100 |
A | GLY102 |
A | LEU103 |
A | ALA104 |
A | SER105 |
A | SER106 |
A | LEU110 |
A | LYS187 |
A | SER191 |
A | SO4401 |
A | DP6403 |
A | CO404 |
A | HOH516 |
A | HOH527 |
A | HOH544 |
A | HOH570 |
A | HOH593 |
site_id | AC3 |
Number of Residues | 20 |
Details | binding site for residue DP6 A 403 |
Chain | Residue |
A | ALA13 |
A | TYR17 |
A | LYS20 |
A | SER106 |
A | SER138 |
A | GLY139 |
A | SER140 |
A | ARG143 |
A | SER191 |
A | ARG192 |
A | MET195 |
A | MET242 |
A | ASP282 |
A | ALA283 |
A | SO4401 |
A | ADP402 |
A | CO404 |
A | CO405 |
A | HOH516 |
A | HOH539 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue CO A 404 |
Chain | Residue |
A | SER106 |
A | SO4401 |
A | ADP402 |
A | DP6403 |
A | HOH518 |
site_id | AC5 |
Number of Residues | 4 |
Details | binding site for residue CO A 405 |
Chain | Residue |
A | ASP282 |
A | SO4401 |
A | DP6403 |
A | HOH539 |