6E2Y

MDDEF in complex with MVAPP, ADP, sulfate and cobalt. Anomalous data

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004163	molecular_function	diphosphomevalonate decarboxylase activity
A	0005524	molecular_function	ATP binding
A	0005829	cellular_component	cytosol
A	0006629	biological_process	lipid metabolic process
A	0008299	biological_process	isoprenoid biosynthetic process
A	0016829	molecular_function	lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0019287	biological_process	isopentenyl diphosphate biosynthetic process, mevalonate pathway
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue SO4 A 401

Chain	Residue
A	GLY102
A	CO405
A	HOH518
A	LEU103
A	ALA104
A	SER191
A	ASP282
A	ALA283
A	ADP402
A	DP6403
A	CO404

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site_id	AC2
Number of Residues	21
Details	binding site for residue ADP A 402

Chain	Residue
A	PHE57
A	VAL72
A	SER93
A	ASN95
A	ALA100
A	GLY102
A	LEU103
A	ALA104
A	SER105
A	SER106
A	LEU110
A	LYS187
A	SER191
A	SO4401
A	DP6403
A	CO404
A	HOH516
A	HOH527
A	HOH544
A	HOH570
A	HOH593

---

site_id	AC3
Number of Residues	20
Details	binding site for residue DP6 A 403

Chain	Residue
A	ALA13
A	TYR17
A	LYS20
A	SER106
A	SER138
A	GLY139
A	SER140
A	ARG143
A	SER191
A	ARG192
A	MET195
A	MET242
A	ASP282
A	ALA283
A	SO4401
A	ADP402
A	CO404
A	CO405
A	HOH516
A	HOH539

---

site_id	AC4
Number of Residues	5
Details	binding site for residue CO A 404

Chain	Residue
A	SER106
A	SO4401
A	ADP402
A	DP6403
A	HOH518

---

site_id	AC5
Number of Residues	4
Details	binding site for residue CO A 405

Chain	Residue
A	ASP282
A	SO4401
A	DP6403
A	HOH539

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