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6E1I

HLA-A*0201 single chain trimer with murine H2K alpha 3 domain and HPV.16 E7 peptide YMLDLQPET

Functional Information from GO Data
ChainGOidnamespacecontents
A0001913biological_processT cell mediated cytotoxicity
A0001916biological_processpositive regulation of T cell mediated cytotoxicity
A0002237biological_processresponse to molecule of bacterial origin
A0002474biological_processantigen processing and presentation of peptide antigen via MHC class I
A0002481biological_processantigen processing and presentation of exogenous protein antigen via MHC class Ib, TAP-dependent
A0002502biological_processpeptide antigen assembly with MHC class I protein complex
A0002726biological_processpositive regulation of T cell cytokine production
A0005198molecular_functionstructural molecule activity
A0005515molecular_functionprotein binding
A0005576cellular_componentextracellular region
A0005615cellular_componentextracellular space
A0005794cellular_componentGolgi apparatus
A0005829cellular_componentcytosol
A0005886cellular_componentplasma membrane
A0006826biological_processiron ion transport
A0006879biological_processintracellular iron ion homeostasis
A0006955biological_processimmune response
A0006968biological_processcellular defense response
A0007608biological_processsensory perception of smell
A0007611biological_processlearning or memory
A0009897cellular_componentexternal side of plasma membrane
A0010977biological_processnegative regulation of neuron projection development
A0019885biological_processantigen processing and presentation of endogenous peptide antigen via MHC class I
A0030670cellular_componentphagocytic vesicle membrane
A0033077biological_processT cell differentiation in thymus
A0034756biological_processregulation of iron ion transport
A0042026biological_processprotein refolding
A0042612cellular_componentMHC class I protein complex
A0042802molecular_functionidentical protein binding
A0042803molecular_functionprotein homodimerization activity
A0042824cellular_componentMHC class I peptide loading complex
A0045646biological_processregulation of erythrocyte differentiation
A0048260biological_processpositive regulation of receptor-mediated endocytosis
A0050680biological_processnegative regulation of epithelial cell proliferation
A0050768biological_processnegative regulation of neurogenesis
A0051289biological_processprotein homotetramerization
A0060586biological_processmulticellular organismal-level iron ion homeostasis
A0071281biological_processcellular response to iron ion
A0071283biological_processcellular response to iron(III) ion
A0071316biological_processcellular response to nicotine
A1990000biological_processamyloid fibril formation
A1990712cellular_componentHFE-transferrin receptor complex
A2000774biological_processpositive regulation of cellular senescence
A2000978biological_processnegative regulation of forebrain neuron differentiation
Functional Information from PROSITE/UniProt
site_idPS00290
Number of Residues7
DetailsIG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACRVKH
ChainResidueDetails
ATYR102-HIS108
ATYR400-HIS406

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues6
DetailsBINDING: BINDING => ECO:0000269|PubMed:21943705
ChainResidueDetails
ATYR150
ATHR216
AALA227
ATHR286
ALYS289
ATYR314

site_idSWS_FT_FI2
Number of Residues2
DetailsBINDING: BINDING => ECO:0000269|PubMed:21543847
ChainResidueDetails
ATYR259
ATYR302

site_idSWS_FT_FI3
Number of Residues1
DetailsMOD_RES: Sulfotyrosine => ECO:0000255
ChainResidueDetails
ATYR202

site_idSWS_FT_FI4
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:19159218
ChainResidueDetails
AASN229

site_idSWS_FT_FI5
Number of Residues1
DetailsCARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:3980466
ChainResidueDetails
AASN399

226707

PDB entries from 2024-10-30

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