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6E0N

Structure of Elizabethkingia meningoseptica CdnE cyclic dinucleotide synthase with GTP and Apcpp

Functional Information from GO Data
ChainGOidnamespacecontents
A0005524molecular_functionATP binding
A0005525molecular_functionGTP binding
A0009117biological_processnucleotide metabolic process
A0016779molecular_functionnucleotidyltransferase activity
A0046872molecular_functionmetal ion binding
A0051607biological_processdefense response to virus
A0052621molecular_functiondiguanylate cyclase activity
A0106408molecular_functiondiadenylate cyclase activity
A0140701molecular_function3',3'-cyclic GMP-AMP synthase activity
Functional Information from PDB Data
site_idAC1
Number of Residues14
Detailsbinding site for residue APC A 301
ChainResidue
AGLN47
ASER169
AGTP302
AHOH409
AHOH421
AHOH422
AASP63
ALYS120
AASN121
ALYS122
AASP136
AILE138
APHE159
AILE167

site_idAC2
Number of Residues24
Detailsbinding site for residue GTP A 302
ChainResidue
AGLN47
AGLY48
ASER49
AASN52
AASP63
ALYS197
ATYR201
ASER216
APHE217
AGLU220
AAPC301
AMG304
AHOH401
AHOH406
AHOH407
AHOH413
AHOH419
AHOH422
AHOH438
AHOH445
AHOH472
AHOH481
AHOH488
AHOH528

site_idAC3
Number of Residues20
Detailsbinding site for residue GTP A 303
ChainResidue
APRO14
AASN53
AARG145
AARG187
AARG191
AARG194
AGLU259
APHE264
ATRP265
ASER268
AARG270
AHOH404
AHOH440
AHOH449
AHOH460
AHOH516
AHOH544
AHOH583
AHOH598
AHOH633

site_idAC4
Number of Residues4
Detailsbinding site for residue MG A 304
ChainResidue
AASP63
AGTP302
AHOH419
AHOH438

Functional Information from SwissProt/UniProt
site_idSWS_FT_FI1
Number of Residues8
DetailsBINDING: BINDING => ECO:0000269|PubMed:30787435
ChainResidueDetails
AGLN47
AGLY48
AASP61
AASP63
AASN121
AASP136
ALYS197
ASER216

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PDB entries from 2024-10-30

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