6DXX
Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) in complex with non-covalent benzothiazole-piperazine inhibitor ARN19702, in presence of Triton X-100
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"19159218","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22040171","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30301806","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DXW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DXX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"22040171","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30301806","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DXX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | Active site: {"description":"Nucleophile","evidences":[{"source":"PubMed","id":"17980170","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"18793752","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30301806","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22040171","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 6 |
| Details | Site: {"description":"Important for enzyme activity","evidences":[{"source":"PubMed","id":"18793752","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30301806","evidenceCode":"ECO:0000305"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"17980170","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22040171","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30301806","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DXW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DXX","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI6 |
| Number of Residues | 3 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"17980170","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"22040171","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30301806","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DXW","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
