6DXX
Human N-acylethanolamine-hydrolyzing acid amidase (NAAA) in complex with non-covalent benzothiazole-piperazine inhibitor ARN19702, in presence of Triton X-100
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Nucleophile => ECO:0000269|PubMed:17980170, ECO:0000269|PubMed:18793752, ECO:0000269|PubMed:30301806, ECO:0000305|PubMed:22040171 |
| Chain | Residue | Details |
| B | CYS126 | |
| D | CYS126 | |
| F | CYS126 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | SITE: Important for enzyme activity => ECO:0000269|PubMed:18793752, ECO:0000305|PubMed:30301806 |
| Chain | Residue | Details |
| B | ARG142 | |
| B | ASN287 | |
| D | ARG142 | |
| D | ASN287 | |
| F | ARG142 | |
| F | ASN287 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17980170, ECO:0000269|PubMed:22040171, ECO:0000269|PubMed:30301806, ECO:0007744|PDB:6DXW, ECO:0007744|PDB:6DXX |
| Chain | Residue | Details |
| B | ASN309 | |
| D | ASN309 | |
| F | ASN309 |
| site_id | SWS_FT_FI4 |
| Number of Residues | 3 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000269|PubMed:17980170, ECO:0000269|PubMed:22040171, ECO:0000269|PubMed:30301806, ECO:0007744|PDB:6DXW |
| Chain | Residue | Details |
| B | ASN333 | |
| D | ASN333 | |
| F | ASN333 |
