Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004175 | molecular_function | endopeptidase activity |
| A | 0004252 | molecular_function | serine-type endopeptidase activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005615 | cellular_component | extracellular space |
| A | 0006508 | biological_process | proteolysis |
| A | 0007586 | biological_process | digestion |
| A | 0008236 | molecular_function | serine-type peptidase activity |
| A | 0046872 | molecular_function | metal ion binding |
| A | 0097180 | cellular_component | serine protease inhibitor complex |
| A | 0097655 | molecular_function | serpin family protein binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 9 |
| Details | binding site for residue EDO A 301 |
| Chain | Residue |
| A | CYS196 |
| A | GLN197 |
| A | SER200 |
| A | P5U200 |
| A | SER215 |
| A | HOH476 |
| A | HOH481 |
| A | HOH510 |
| A | HOH516 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 302 |
| Chain | Residue |
| A | GLY68 |
| A | ALA90 |
| A | SER91 |
| A | SER153 |
| A | TYR154 |
| A | HOH407 |
| A | HOH509 |
| A | HOH534 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue EDO A 303 |
| Chain | Residue |
| A | ARG72 |
| A | ILE78 |
| A | VAL81 |
| A | VAL95 |
| A | HIS96 |
| A | PRO97 |
| A | HOH462 |
| A | HOH470 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 304 |
| Chain | Residue |
| A | ASN105 |
| A | SER115 |
| A | ALA116 |
| A | HOH414 |
| A | HOH415 |
| A | HOH444 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 305 |
| Chain | Residue |
| A | GLU75 |
| A | ASN77 |
| A | VAL80 |
| A | GLU85 |
| A | HOH422 |
| A | HOH470 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 307 |
| Chain | Residue |
| A | GLN197 |
| A | P5U200 |
| A | HOH504 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue CA A 308 |
| Chain | Residue |
| A | ASN100 |
| A | ALA116 |
| A | HOH446 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 309 |
| Chain | Residue |
| A | LYS92 |
| A | LYS112 |
| A | THR152 |
| A | GLN197 |
| A | HOH545 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VSAAHC |
| Chain | Residue | Details |
| A | VAL59-CYS64 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 3 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| A | HIS63 | |
| A | ASP107 | |
| A | P5U200 | |
| site_id | SWS_FT_FI2 |
| Number of Residues | 7 |
| Details | BINDING: |
| Chain | Residue | Details |
| A | GLU75 | |
| A | ASN77 | |
| A | VAL80 | |
| A | GLU85 | |
| A | ASP194 | |
| A | GLN197 | |
| A | P5U200 | |
