Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0010181 | molecular_function | FMN binding |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0050040 | molecular_function | lactate 2-monooxygenase activity |
| B | 0004497 | molecular_function | monooxygenase activity |
| B | 0010181 | molecular_function | FMN binding |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0050040 | molecular_function | lactate 2-monooxygenase activity |
| C | 0004497 | molecular_function | monooxygenase activity |
| C | 0010181 | molecular_function | FMN binding |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0050040 | molecular_function | lactate 2-monooxygenase activity |
| D | 0004497 | molecular_function | monooxygenase activity |
| D | 0010181 | molecular_function | FMN binding |
| D | 0016491 | molecular_function | oxidoreductase activity |
| D | 0050040 | molecular_function | lactate 2-monooxygenase activity |
| E | 0004497 | molecular_function | monooxygenase activity |
| E | 0010181 | molecular_function | FMN binding |
| E | 0016491 | molecular_function | oxidoreductase activity |
| E | 0050040 | molecular_function | lactate 2-monooxygenase activity |
| F | 0004497 | molecular_function | monooxygenase activity |
| F | 0010181 | molecular_function | FMN binding |
| F | 0016491 | molecular_function | oxidoreductase activity |
| F | 0050040 | molecular_function | lactate 2-monooxygenase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 23 |
| Details | binding site for residue FMN A 401 |
| Chain | Residue |
| A | ALA96 |
| A | SER288 |
| A | HIS290 |
| A | GLY291 |
| A | ARG293 |
| A | ASP320 |
| A | SER321 |
| A | GLY322 |
| A | ARG324 |
| A | GLY343 |
| A | ARG344 |
| A | PRO97 |
| A | SO4403 |
| A | HOH598 |
| A | HOH602 |
| A | HOH709 |
| A | ILE98 |
| A | GLY99 |
| A | SER128 |
| A | GLN150 |
| A | TYR152 |
| A | THR178 |
| A | LYS266 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 402 |
| Chain | Residue |
| A | HIS53 |
| A | ARG56 |
| A | LYS63 |
| A | HOH642 |
| A | HOH657 |
| A | HOH774 |
| site_id | AC3 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 A 403 |
| Chain | Residue |
| A | TYR44 |
| A | TYR152 |
| A | PHE184 |
| A | ARG187 |
| A | HIS290 |
| A | ARG293 |
| A | FMN401 |
| A | HOH505 |
| A | HOH523 |
| A | HOH709 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 A 404 |
| Chain | Residue |
| A | HIS270 |
| A | ASP387 |
| A | HOH576 |
| A | HOH595 |
| A | HOH773 |
| B | PRO271 |
| B | ASP272 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 405 |
| Chain | Residue |
| A | GLN116 |
| A | HIS141 |
| A | HOH623 |
| site_id | AC6 |
| Number of Residues | 24 |
| Details | binding site for residue FMN B 401 |
| Chain | Residue |
| B | ALA96 |
| B | PRO97 |
| B | ILE98 |
| B | GLY99 |
| B | VAL100 |
| B | SER128 |
| B | GLN150 |
| B | TYR152 |
| B | THR178 |
| B | LYS266 |
| B | SER288 |
| B | HIS290 |
| B | GLY291 |
| B | ARG293 |
| B | ASP320 |
| B | SER321 |
| B | GLY322 |
| B | ARG324 |
| B | GLY343 |
| B | ARG344 |
| B | SO4403 |
| B | HOH605 |
| B | HOH647 |
| B | HOH749 |
| site_id | AC7 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 402 |
| Chain | Residue |
| B | HIS53 |
| B | ARG56 |
| B | LYS63 |
| B | HOH537 |
| B | HOH588 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 403 |
| Chain | Residue |
| B | TYR44 |
| B | ARG187 |
| B | HIS290 |
| B | ARG293 |
| B | FMN401 |
| B | HOH502 |
| B | HOH749 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 B 404 |
| Chain | Residue |
| A | LYS310 |
| A | HOH954 |
| B | LYS310 |
| B | HOH509 |
| B | HOH596 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 405 |
| Chain | Residue |
| B | GLN116 |
| B | HIS141 |
| B | HOH505 |
| site_id | AD2 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 B 406 |
| Chain | Residue |
| B | HOH757 |
| A | ASP272 |
| A | HOH527 |
| B | HIS270 |
| B | ASP387 |
| B | ARG390 |
| B | HOH682 |
| site_id | AD3 |
| Number of Residues | 23 |
| Details | binding site for residue FMN C 401 |
| Chain | Residue |
| C | ALA96 |
| C | PRO97 |
| C | ILE98 |
| C | GLY99 |
| C | SER128 |
| C | GLN150 |
| C | TYR152 |
| C | THR178 |
| C | LYS266 |
| C | SER288 |
| C | HIS290 |
| C | GLY291 |
| C | ARG293 |
| C | ASP320 |
| C | SER321 |
| C | GLY322 |
| C | ARG324 |
| C | GLY343 |
| C | ARG344 |
| C | SO4402 |
| C | HOH546 |
| C | HOH598 |
| C | HOH670 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue SO4 C 402 |
| Chain | Residue |
| C | TYR44 |
| C | TYR152 |
| C | PHE184 |
| C | ARG187 |
| C | HIS290 |
| C | ARG293 |
| C | FMN401 |
| C | HOH501 |
| C | HOH504 |
| C | HOH670 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 C 403 |
| Chain | Residue |
| C | HIS53 |
| C | ARG56 |
| C | LYS63 |
| C | HOH573 |
| C | HOH590 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 404 |
| Chain | Residue |
| C | GLN116 |
| C | HIS141 |
| C | HOH585 |
| site_id | AD7 |
| Number of Residues | 21 |
| Details | binding site for residue FMN D 401 |
| Chain | Residue |
| D | ALA96 |
| D | PRO97 |
| D | ILE98 |
| D | GLY99 |
| D | SER128 |
| D | GLN150 |
| D | TYR152 |
| D | THR178 |
| D | LYS266 |
| D | SER288 |
| D | HIS290 |
| D | GLY291 |
| D | ARG293 |
| D | ASP320 |
| D | SER321 |
| D | GLY322 |
| D | ARG324 |
| D | ARG344 |
| D | SO4403 |
| D | HOH512 |
| D | HOH541 |
| site_id | AD8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 402 |
| Chain | Residue |
| D | HIS53 |
| D | ARG56 |
| D | LYS63 |
| D | HOH530 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue SO4 D 403 |
| Chain | Residue |
| D | TYR44 |
| D | TYR152 |
| D | PHE184 |
| D | ARG187 |
| D | HIS290 |
| D | ARG293 |
| D | FMN401 |
| D | HOH506 |
| site_id | AE1 |
| Number of Residues | 23 |
| Details | binding site for residue FMN E 401 |
| Chain | Residue |
| E | VAL45 |
| E | PRO97 |
| E | ILE98 |
| E | GLY99 |
| E | VAL100 |
| E | SER128 |
| E | GLN150 |
| E | TYR152 |
| E | THR178 |
| E | LYS266 |
| E | SER288 |
| E | HIS290 |
| E | GLY291 |
| E | ARG293 |
| E | ASP320 |
| E | SER321 |
| E | GLY322 |
| E | ARG324 |
| E | GLY343 |
| E | ARG344 |
| E | SO4403 |
| E | HOH502 |
| E | HOH505 |
| site_id | AE2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 402 |
| Chain | Residue |
| E | HIS53 |
| E | ARG56 |
| E | LYS63 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 E 403 |
| Chain | Residue |
| E | TYR44 |
| E | TYR152 |
| E | PHE184 |
| E | ARG187 |
| E | HIS290 |
| E | ARG293 |
| E | FMN401 |
| site_id | AE4 |
| Number of Residues | 21 |
| Details | binding site for residue FMN F 401 |
| Chain | Residue |
| F | ALA96 |
| F | PRO97 |
| F | ILE98 |
| F | GLY99 |
| F | VAL100 |
| F | SER128 |
| F | GLN150 |
| F | TYR152 |
| F | THR178 |
| F | LYS266 |
| F | SER288 |
| F | HIS290 |
| F | GLY291 |
| F | ARG293 |
| F | ASP320 |
| F | SER321 |
| F | GLY322 |
| F | ARG324 |
| F | ARG344 |
| F | SO4402 |
| F | HOH505 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 F 402 |
| Chain | Residue |
| F | TYR44 |
| F | TYR152 |
| F | PHE184 |
| F | ARG187 |
| F | HIS290 |
| F | ARG293 |
| F | FMN401 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 403 |
| Chain | Residue |
| F | HIS53 |
| F | ARG56 |
| F | LYS63 |
Functional Information from PROSITE/UniProt
| site_id | PS00557 |
| Number of Residues | 7 |
| Details | FMN_HYDROXY_ACID_DH_1 FMN-dependent alpha-hydroxy acid dehydrogenases active site. SNHGGRQ |
| Chain | Residue | Details |
| A | SER288-GLN294 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2250 |
| Details | Domain: {"description":"FMN hydroxy acid dehydrogenase","evidences":[{"source":"PROSITE-ProRule","id":"PRU00683","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 6 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"source":"PROSITE-ProRule","id":"PRU00683","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 24 |
| Details | Binding site: {"evidences":[{"source":"PROSITE-ProRule","id":"PRU00683","evidenceCode":"ECO:0000255"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 66 |
| Details | Binding site: {"evidences":[{"source":"PubMed","id":"30207005","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DVI","evidenceCode":"ECO:0007744"}]} |
