6DV1

Crystal structure of the alpha-E-catenin actin-binding domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0007155	biological_process	cell adhesion
A	0045296	molecular_function	cadherin binding
A	0051015	molecular_function	actin filament binding
B	0007155	biological_process	cell adhesion
B	0045296	molecular_function	cadherin binding
B	0051015	molecular_function	actin filament binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	2
Details	binding site for residue BR A 1001

Chain	Residue
A	LYS683
A	LYS704

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site_id	AC2
Number of Residues	1
Details	binding site for residue BR A 1002

Chain	Residue
A	HIS766

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site_id	AC3
Number of Residues	4
Details	binding site for residue SO4 A 1003

Chain	Residue
A	SER668
A	ARG670
A	LYS737
A	HOH1120

---

site_id	AC4
Number of Residues	3
Details	binding site for residue BR B 1001

Chain	Residue
B	HOH1134
B	SER668
B	ARG670

---

site_id	AC5
Number of Residues	3
Details	binding site for residue BR B 1002

Chain	Residue
B	GLN692
B	MET724
B	THR727

---

site_id	AC6
Number of Residues	1
Details	binding site for residue BR B 1003

Chain	Residue
A	GLN678

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site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 B 1004

Chain	Residue
A	LEU785
A	HIS788
B	TYR779
B	ARG782
B	GLN831

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Modified residue: {"description":"Phosphothreonine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI2
Number of Residues	4
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)","evidences":[{"source":"UniProtKB","id":"P35221","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

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site_id	SWS_FT_FI3
Number of Residues	2
Details	Modified residue: {"description":"Phosphoserine","evidences":[{"source":"PubMed","id":"21183079","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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