6DNJ

Directed evolutionary changes in Kemp Eliminase KE07 - Crystal 28 round 5

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000105	biological_process	L-histidine biosynthetic process
A	0000107	molecular_function	imidazoleglycerol-phosphate synthase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residues MPD A 301 and H5J A 302

Chain	Residue
A	TRP50
A	HOH430
A	HOH674
A	ILE52
A	GLY80
A	GLY81
A	GLU101
A	ASN103
A	TYR128
A	HOH402
A	HOH404

---

site_id	AC2
Number of Residues	11
Details	binding site for residues MPD A 301 and H5J A 302

Chain	Residue
A	TRP50
A	ILE52
A	GLY80
A	GLY81
A	GLU101
A	ASN103
A	TYR128
A	HOH402
A	HOH404
A	HOH430
A	HOH674

---

site_id	AC3
Number of Residues	11
Details	binding site for residues MPD A 301 and H5J A 302

Chain	Residue
A	TRP50
A	ILE52
A	GLY80
A	GLY81
A	GLU101
A	ASN103
A	TYR128
A	HOH402
A	HOH404
A	HOH430
A	HOH674

---

site_id	AC4
Number of Residues	11
Details	binding site for residues MPD A 301 and H5J A 302

Chain	Residue
A	TRP50
A	ILE52
A	GLY80
A	GLY81
A	GLU101
A	ASN103
A	TYR128
A	HOH402
A	HOH404
A	HOH430
A	HOH674

---

site_id	AC5
Number of Residues	11
Details	binding site for residues MPD A 301 and H5J A 302

Chain	Residue
A	TRP50
A	ILE52
A	GLY80
A	GLY81
A	GLU101
A	ASN103
A	TYR128
A	HOH402
A	HOH404
A	HOH430
A	HOH674

---

site_id	AC6
Number of Residues	11
Details	binding site for residues MPD A 301 and H5J A 302

Chain	Residue
A	TRP50
A	ILE52
A	GLY80
A	GLY81
A	GLU101
A	ASN103
A	TYR128
A	HOH402
A	HOH404
A	HOH430
A	HOH674

---

site_id	AC7
Number of Residues	11
Details	binding site for residues MPD A 301 and H5J A 302

Chain	Residue
A	TRP50
A	ILE52
A	GLY80
A	GLY81
A	GLU101
A	ASN103
A	TYR128
A	HOH402
A	HOH404
A	HOH430
A	HOH674

---

site_id	AC8
Number of Residues	11
Details	binding site for residues MPD A 301 and H5J A 302

Chain	Residue
A	TRP50
A	ILE52
A	GLY80
A	GLY81
A	GLU101
A	ASN103
A	TYR128
A	HOH402
A	HOH404
A	HOH430
A	HOH674

---