6DMO

Cryo-EM structure of human Ptch1 with three mutations L282Q/T500F/P504L

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000122	biological_process	negative regulation of transcription by RNA polymerase II
A	0001841	biological_process	neural tube formation
A	0005113	molecular_function	patched binding
A	0005119	molecular_function	smoothened binding
A	0005515	molecular_function	protein binding
A	0005794	cellular_component	Golgi apparatus
A	0005886	cellular_component	plasma membrane
A	0005901	cellular_component	caveola
A	0005929	cellular_component	cilium
A	0007165	biological_process	signal transduction
A	0007286	biological_process	spermatid development
A	0007420	biological_process	brain development
A	0008158	molecular_function	hedgehog receptor activity
A	0008201	molecular_function	heparin binding
A	0008589	biological_process	regulation of smoothened signaling pathway
A	0009410	biological_process	response to xenobiotic stimulus
A	0009612	biological_process	response to mechanical stimulus
A	0009887	biological_process	animal organ morphogenesis
A	0009953	biological_process	dorsal/ventral pattern formation
A	0010875	biological_process	positive regulation of cholesterol efflux
A	0015485	molecular_function	cholesterol binding
A	0016020	cellular_component	membrane
A	0016485	biological_process	protein processing
A	0021532	biological_process	neural tube patterning
A	0021997	biological_process	neural plate axis specification
A	0030326	biological_process	embryonic limb morphogenesis
A	0030332	molecular_function	cyclin binding
A	0030496	cellular_component	midbody
A	0030666	cellular_component	endocytic vesicle membrane
A	0030850	biological_process	prostate gland development
A	0032355	biological_process	response to estradiol
A	0032526	biological_process	response to retinoic acid
A	0032880	biological_process	regulation of protein localization
A	0034204	biological_process	lipid translocation
A	0035108	biological_process	limb morphogenesis
A	0040015	biological_process	negative regulation of multicellular organism growth
A	0043279	biological_process	response to alkaloid
A	0044294	cellular_component	dendritic growth cone
A	0044295	cellular_component	axonal growth cone
A	0044877	molecular_function	protein-containing complex binding
A	0045177	cellular_component	apical part of cell
A	0045211	cellular_component	postsynaptic membrane
A	0045668	biological_process	negative regulation of osteoblast differentiation
A	0045879	biological_process	negative regulation of smoothened signaling pathway
A	0045892	biological_process	negative regulation of DNA-templated transcription
A	0045893	biological_process	positive regulation of DNA-templated transcription
A	0048471	cellular_component	perinuclear region of cytoplasm
A	0048745	biological_process	smooth muscle tissue development
A	0051782	biological_process	negative regulation of cell division
A	0060037	biological_process	pharyngeal system development
A	0060170	cellular_component	ciliary membrane
A	0061053	biological_process	somite development
A	0071397	biological_process	cellular response to cholesterol
A	0071679	biological_process	commissural neuron axon guidance
A	0072205	biological_process	metanephric collecting duct development
A	0072659	biological_process	protein localization to plasma membrane
A	0097108	molecular_function	hedgehog family protein binding
A	0097421	biological_process	liver regeneration
A	0098804	cellular_component	non-motile cilium membrane
A	0140303	molecular_function	intramembrane lipid carrier activity

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	17
Details	Transmembrane: {"description":"Helical; Name=TM1","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	19
Details	Transmembrane: {"description":"Helical; Name=TM2","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	52
Details	Topological domain: {"description":"Cytoplasmic","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=TM3","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	288
Details	Topological domain: {"description":"Extracellular","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI6
Number of Residues	18
Details	Transmembrane: {"description":"Helical; Name=TM4","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI7
Number of Residues	20
Details	Transmembrane: {"description":"Helical; Name=TM5","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI8
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=TM6","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI9
Number of Residues	21
Details	Transmembrane: {"description":"Helical; Name=TM7","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI10
Number of Residues	19
Details	Transmembrane: {"description":"Helical; Name=TM8","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI11
Number of Residues	24
Details	Transmembrane: {"description":"Helical; Name=TM9","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI12
Number of Residues	18
Details	Transmembrane: {"description":"Helical; Name=TM10","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI13
Number of Residues	20
Details	Transmembrane: {"description":"Helical; Name=TM11","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI14
Number of Residues	22
Details	Transmembrane: {"description":"Helical; Name=TM12","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"29995851","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30139912","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6E1H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEU","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6OEV","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI15
Number of Residues	160
Details	Domain: {"description":"SSD","evidences":[{"source":"PROSITE-ProRule","id":"PRU00199","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI16
Number of Residues	257
Details	Region: {"description":"Extracellular domain 2 (ECD2)","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI17
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31548691","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RVD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI18
Number of Residues	2
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31548691","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RTW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RTX","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RVD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI19
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31548691","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RTW","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RTY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RVD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI20
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"29954986","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31127104","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31548691","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"31555730","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6DMB","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMO","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6DMY","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7G","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7H","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6N7K","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RMG","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RVC","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"6RVD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI21
Number of Residues	1
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"source":"PubMed","id":"31548691","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6RVD","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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