Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004672 | molecular_function | protein kinase activity |
| A | 0004713 | molecular_function | protein tyrosine kinase activity |
| A | 0004714 | molecular_function | transmembrane receptor protein tyrosine kinase activity |
| A | 0005524 | molecular_function | ATP binding |
| A | 0006468 | biological_process | protein phosphorylation |
| A | 0007169 | biological_process | cell surface receptor protein tyrosine kinase signaling pathway |
| A | 0016020 | cellular_component | membrane |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue 22L A 801 |
| Chain | Residue |
| A | LYS513 |
| A | TRP514 |
| A | GLU515 |
| A | PHE525 |
| A | ALA545 |
| A | LYS547 |
| A | HOH956 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue GOD A 802 |
| Chain | Residue |
| A | LEU564 |
| A | LEU567 |
| A | PHE589 |
| A | GLU590 |
| A | MET592 |
| A | LEU641 |
| A | LEU657 |
| A | ILE666 |
| A | GLY667 |
| A | ASP668 |
| A | PHE669 |
| A | HOH969 |
| A | VAL524 |
| A | ALA542 |
Functional Information from PROSITE/UniProt
| site_id | PS00107 |
| Number of Residues | 29 |
| Details | PROTEIN_KINASE_ATP Protein kinases ATP-binding region signature. LGEGAFGKVFlAechnllpeqdkml.....VAVK |
| Chain | Residue | Details |
| A | LEU516-LYS544 | |
| site_id | PS00109 |
| Number of Residues | 13 |
| Details | PROTEIN_KINASE_TYR Tyrosine protein kinases specific active-site signature. FVHrDLATRNCLV |
| Chain | Residue | Details |
| A | PHE646-VAL658 | |
| site_id | PS00239 |
| Number of Residues | 9 |
| Details | RECEPTOR_TYR_KIN_II Receptor tyrosine kinase class II signature. DIYstdYYR |
| Chain | Residue | Details |
| A | ASP674-ARG682 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 15 |
| Details | TRANSMEM: Helical => ECO:0000255 |
| Chain | Residue | Details |
| A | GLY522-ASP537 | |
| Chain | Residue | Details |
| A | ARG748 | |
| Chain | Residue | Details |
| A | GLY614 | |
| A | ALA642 | |
| site_id | SWS_FT_FI4 |
| Number of Residues | 1 |
| Details | SITE: Breakpoint for translocation to form TRK and TRK-T3 |
| Chain | Residue | Details |
| A | TYR496 | |
| site_id | SWS_FT_FI5 |
| Number of Residues | 1 |
| Details | SITE: Breakpoint for translocation to form TRK-T1 |
| Chain | Residue | Details |
| A | PRO584 | |
| site_id | SWS_FT_FI6 |
| Number of Residues | 1 |
| Details | SITE: Interaction with SHC1 |
| Chain | Residue | Details |
| A | HIS594 | |
| Chain | Residue | Details |
| A | HIS594 | |
| Chain | Residue | Details |
| A | ILE774 | |
| Chain | Residue | Details |
| A | HIS778 | |
| A | ALA779 | |
| site_id | SWS_FT_FI10 |
| Number of Residues | 1 |
| Details | CARBOHYD: N-linked (GlcNAc...) asparagine => ECO:0000255 |
| Chain | Residue | Details |
| A | ASP499 | |
