6DJM
Cryo-EM structure of AMPPNP-actin filaments
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0001725 | cellular_component | stress fiber |
| A | 0005200 | molecular_function | structural constituent of cytoskeleton |
| A | 0005515 | molecular_function | protein binding |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005856 | cellular_component | cytoskeleton |
| A | 0005865 | cellular_component | striated muscle thin filament |
| A | 0005884 | cellular_component | actin filament |
| A | 0015629 | cellular_component | actin cytoskeleton |
| A | 0016787 | molecular_function | hydrolase activity |
| A | 0030240 | biological_process | skeletal muscle thin filament assembly |
| A | 0048741 | biological_process | skeletal muscle fiber development |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0001725 | cellular_component | stress fiber |
| B | 0005200 | molecular_function | structural constituent of cytoskeleton |
| B | 0005515 | molecular_function | protein binding |
| B | 0005524 | molecular_function | ATP binding |
| B | 0005856 | cellular_component | cytoskeleton |
| B | 0005865 | cellular_component | striated muscle thin filament |
| B | 0005884 | cellular_component | actin filament |
| B | 0015629 | cellular_component | actin cytoskeleton |
| B | 0016787 | molecular_function | hydrolase activity |
| B | 0030240 | biological_process | skeletal muscle thin filament assembly |
| B | 0048741 | biological_process | skeletal muscle fiber development |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0001725 | cellular_component | stress fiber |
| C | 0005200 | molecular_function | structural constituent of cytoskeleton |
| C | 0005515 | molecular_function | protein binding |
| C | 0005524 | molecular_function | ATP binding |
| C | 0005856 | cellular_component | cytoskeleton |
| C | 0005865 | cellular_component | striated muscle thin filament |
| C | 0005884 | cellular_component | actin filament |
| C | 0015629 | cellular_component | actin cytoskeleton |
| C | 0016787 | molecular_function | hydrolase activity |
| C | 0030240 | biological_process | skeletal muscle thin filament assembly |
| C | 0048741 | biological_process | skeletal muscle fiber development |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0001725 | cellular_component | stress fiber |
| D | 0005200 | molecular_function | structural constituent of cytoskeleton |
| D | 0005515 | molecular_function | protein binding |
| D | 0005524 | molecular_function | ATP binding |
| D | 0005856 | cellular_component | cytoskeleton |
| D | 0005865 | cellular_component | striated muscle thin filament |
| D | 0005884 | cellular_component | actin filament |
| D | 0015629 | cellular_component | actin cytoskeleton |
| D | 0016787 | molecular_function | hydrolase activity |
| D | 0030240 | biological_process | skeletal muscle thin filament assembly |
| D | 0048741 | biological_process | skeletal muscle fiber development |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue MG A 801 |
| Chain | Residue |
| A | ANP802 |
| site_id | AC2 |
| Number of Residues | 14 |
| Details | binding site for residue ANP A 802 |
| Chain | Residue |
| A | GLU214 |
| A | GLY301 |
| A | GLY302 |
| A | TYR306 |
| A | LYS336 |
| A | MG801 |
| A | GLY13 |
| A | SER14 |
| A | LEU16 |
| A | LYS18 |
| A | GLN137 |
| A | GLY156 |
| A | ASP157 |
| A | LYS213 |
| site_id | AC3 |
| Number of Residues | 1 |
| Details | binding site for residue MG B 801 |
| Chain | Residue |
| B | ANP802 |
| site_id | AC4 |
| Number of Residues | 14 |
| Details | binding site for residue ANP B 802 |
| Chain | Residue |
| B | GLY13 |
| B | SER14 |
| B | GLY15 |
| B | LEU16 |
| B | LYS18 |
| B | GLY156 |
| B | ASP157 |
| B | LYS213 |
| B | GLU214 |
| B | GLY301 |
| B | GLY302 |
| B | TYR306 |
| B | LYS336 |
| B | MG801 |
| site_id | AC5 |
| Number of Residues | 1 |
| Details | binding site for residue MG C 801 |
| Chain | Residue |
| C | ANP802 |
| site_id | AC6 |
| Number of Residues | 17 |
| Details | binding site for residue ANP C 802 |
| Chain | Residue |
| C | GLY13 |
| C | SER14 |
| C | GLY15 |
| C | LEU16 |
| C | LYS18 |
| C | GLN137 |
| C | GLY156 |
| C | ASP157 |
| C | LYS213 |
| C | GLU214 |
| C | GLY301 |
| C | GLY302 |
| C | THR303 |
| C | TYR306 |
| C | LYS336 |
| C | MG801 |
| C | HOH901 |
| site_id | AC7 |
| Number of Residues | 1 |
| Details | binding site for residue MG D 801 |
| Chain | Residue |
| D | ANP802 |
| site_id | AC8 |
| Number of Residues | 13 |
| Details | binding site for residue ANP D 802 |
| Chain | Residue |
| D | GLY13 |
| D | SER14 |
| D | LEU16 |
| D | LYS18 |
| D | GLY156 |
| D | ASP157 |
| D | LYS213 |
| D | GLU214 |
| D | GLY301 |
| D | GLY302 |
| D | TYR306 |
| D | LYS336 |
| D | MG801 |
Functional Information from PROSITE/UniProt
| site_id | PS00406 |
| Number of Residues | 11 |
| Details | ACTINS_1 Actins signature 1. YVGDEAQs.KRG |
| Chain | Residue | Details |
| A | TYR53-GLY63 |
| site_id | PS00432 |
| Number of Residues | 9 |
| Details | ACTINS_2 Actins signature 2. WITKqEYDE |
| Chain | Residue | Details |
| A | TRP356-GLU364 |
| site_id | PS01132 |
| Number of Residues | 13 |
| Details | ACTINS_ACT_LIKE Actins and actin-related proteins signature. LLTEApLNPkaNR |
| Chain | Residue | Details |
| A | LEU104-ARG116 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 8 |
| Details | Modified residue: {"description":"Methionine (R)-sulfoxide","evidences":[{"source":"UniProtKB","id":"P68134","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"Tele-methylhistidine","evidences":[{"source":"PubMed","id":"12356759","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"1MDU","evidenceCode":"ECO:0007744"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 4 |
| Details | Modified residue: {"description":"N6-methyllysine","evidences":[{"source":"UniProtKB","id":"P68133","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
