Functional Information from GO Data
| Chain | GOid | namespace | contents |
| B | 0004252 | molecular_function | serine-type endopeptidase activity |
| B | 0006508 | biological_process | proteolysis |
| C | 0004252 | molecular_function | serine-type endopeptidase activity |
| C | 0006508 | biological_process | proteolysis |
| E | 0004252 | molecular_function | serine-type endopeptidase activity |
| E | 0006508 | biological_process | proteolysis |
| F | 0004252 | molecular_function | serine-type endopeptidase activity |
| F | 0006508 | biological_process | proteolysis |
| H | 0004252 | molecular_function | serine-type endopeptidase activity |
| H | 0006508 | biological_process | proteolysis |
| I | 0004252 | molecular_function | serine-type endopeptidase activity |
| I | 0006508 | biological_process | proteolysis |
| K | 0004252 | molecular_function | serine-type endopeptidase activity |
| K | 0006508 | biological_process | proteolysis |
| L | 0004252 | molecular_function | serine-type endopeptidase activity |
| L | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 B 201 |
| Chain | Residue |
| B | GLY59 |
| B | LYS90 |
| B | HOH308 |
| B | HOH351 |
| B | HOH384 |
| K | ARG145 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 202 |
| Chain | Residue |
| B | ASN95 |
| B | ASN100 |
| B | ASN101 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 203 |
| Chain | Residue |
| B | THR61 |
| B | SER63 |
| B | HOH321 |
| B | HOH357 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 C 301 |
| Chain | Residue |
| C | ASN236 |
| C | HOH402 |
| C | HOH406 |
| C | HOH421 |
| C | HOH432 |
| H | HOH301 |
| I | ASN236 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 C 302 |
| Chain | Residue |
| C | TRP172 |
| C | SER217 |
| C | SER218 |
| C | HOH404 |
| C | HOH434 |
| C | HOH458 |
| L | SO4302 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 E 201 |
| Chain | Residue |
| E | SER92 |
| E | HOH307 |
| E | HOH324 |
| E | HOH328 |
| E | HOH329 |
| F | TRP237 |
| site_id | AC7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 E 202 |
| Chain | Residue |
| E | ASN95 |
| E | ASN100 |
| E | ASN101 |
| E | HOH302 |
| site_id | AC8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 H 201 |
| Chain | Residue |
| H | ASN95 |
| H | ASN100 |
| H | ASN101 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 I 301 |
| Chain | Residue |
| F | LYS175 |
| I | TRP172 |
| I | SER218 |
| I | HOH907 |
| I | HOH915 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 K 201 |
| Chain | Residue |
| K | SER92 |
| K | HOH317 |
| K | HOH318 |
| K | HOH341 |
| K | HOH356 |
| L | TRP237 |
| site_id | AD2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 K 202 |
| Chain | Residue |
| K | ASN100 |
| K | ASN101 |
| K | HOH312 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 L 301 |
| Chain | Residue |
| F | ASN236 |
| L | ASN236 |
| L | HOH401 |
| L | HOH402 |
| L | HOH411 |
| L | HOH446 |
| L | HOH449 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue SO4 L 302 |
| Chain | Residue |
| C | TRP172 |
| C | LYS175 |
| C | SO4302 |
| C | HOH434 |
| L | TRP172 |
| L | SER218 |
| L | HOH403 |
Functional Information from PROSITE/UniProt
| site_id | PS00134 |
| Number of Residues | 6 |
| Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
| Chain | Residue | Details |
| B | VAL53-CYS58 | |
| site_id | PS00135 |
| Number of Residues | 12 |
| Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScmGDSGGPLV |
| Chain | Residue | Details |
| C | SER189-VAL200 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 4 |
| Details | ACT_SITE: Charge relay system |
| Chain | Residue | Details |
| C | SER195 | |
| F | SER195 | |
| I | SER195 | |
| L | SER195 | |
| H | HIS57 | |
| H | ASP102 | |
| K | HIS57 | |
| K | ASP102 | |
Catalytic Information from CSA
| site_id | MCSA1 |
| Number of Residues | 3 |
| Details | M-CSA 387 |
| Chain | Residue | Details |
| C | GLY193 | electrostatic stabiliser |
| C | SER195 | covalent catalysis |
| C | GLY196 | electrostatic stabiliser |
| site_id | MCSA2 |
| Number of Residues | 3 |
| Details | M-CSA 387 |
| Chain | Residue | Details |
| F | GLY193 | electrostatic stabiliser |
| F | SER195 | covalent catalysis |
| F | GLY196 | electrostatic stabiliser |
| site_id | MCSA3 |
| Number of Residues | 3 |
| Details | M-CSA 387 |
| Chain | Residue | Details |
| I | GLY193 | electrostatic stabiliser |
| I | SER195 | covalent catalysis |
| I | GLY196 | electrostatic stabiliser |
| site_id | MCSA4 |
| Number of Residues | 3 |
| Details | M-CSA 387 |
| Chain | Residue | Details |
| L | GLY193 | electrostatic stabiliser |
| L | SER195 | covalent catalysis |
| L | GLY196 | electrostatic stabiliser |
