Functional Information from GO Data
Chain | GOid | namespace | contents |
B | 0004252 | molecular_function | serine-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
C | 0004252 | molecular_function | serine-type endopeptidase activity |
C | 0006508 | biological_process | proteolysis |
E | 0004252 | molecular_function | serine-type endopeptidase activity |
E | 0006508 | biological_process | proteolysis |
F | 0004252 | molecular_function | serine-type endopeptidase activity |
F | 0006508 | biological_process | proteolysis |
H | 0004252 | molecular_function | serine-type endopeptidase activity |
H | 0006508 | biological_process | proteolysis |
I | 0004252 | molecular_function | serine-type endopeptidase activity |
I | 0006508 | biological_process | proteolysis |
K | 0004252 | molecular_function | serine-type endopeptidase activity |
K | 0006508 | biological_process | proteolysis |
L | 0004252 | molecular_function | serine-type endopeptidase activity |
L | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue SO4 B 201 |
Chain | Residue |
B | GLY59 |
B | LYS90 |
B | HOH308 |
B | HOH351 |
B | HOH384 |
K | ARG145 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue SO4 B 202 |
Chain | Residue |
B | ASN95 |
B | ASN100 |
B | ASN101 |
site_id | AC3 |
Number of Residues | 4 |
Details | binding site for residue SO4 B 203 |
Chain | Residue |
B | THR61 |
B | SER63 |
B | HOH321 |
B | HOH357 |
site_id | AC4 |
Number of Residues | 7 |
Details | binding site for residue SO4 C 301 |
Chain | Residue |
C | ASN236 |
C | HOH402 |
C | HOH406 |
C | HOH421 |
C | HOH432 |
H | HOH301 |
I | ASN236 |
site_id | AC5 |
Number of Residues | 7 |
Details | binding site for residue SO4 C 302 |
Chain | Residue |
C | TRP172 |
C | SER217 |
C | SER218 |
C | HOH404 |
C | HOH434 |
C | HOH458 |
L | SO4302 |
site_id | AC6 |
Number of Residues | 6 |
Details | binding site for residue SO4 E 201 |
Chain | Residue |
E | SER92 |
E | HOH307 |
E | HOH324 |
E | HOH328 |
E | HOH329 |
F | TRP237 |
site_id | AC7 |
Number of Residues | 4 |
Details | binding site for residue SO4 E 202 |
Chain | Residue |
E | ASN95 |
E | ASN100 |
E | ASN101 |
E | HOH302 |
site_id | AC8 |
Number of Residues | 3 |
Details | binding site for residue SO4 H 201 |
Chain | Residue |
H | ASN95 |
H | ASN100 |
H | ASN101 |
site_id | AC9 |
Number of Residues | 5 |
Details | binding site for residue SO4 I 301 |
Chain | Residue |
F | LYS175 |
I | TRP172 |
I | SER218 |
I | HOH907 |
I | HOH915 |
site_id | AD1 |
Number of Residues | 6 |
Details | binding site for residue SO4 K 201 |
Chain | Residue |
K | SER92 |
K | HOH317 |
K | HOH318 |
K | HOH341 |
K | HOH356 |
L | TRP237 |
site_id | AD2 |
Number of Residues | 3 |
Details | binding site for residue SO4 K 202 |
Chain | Residue |
K | ASN100 |
K | ASN101 |
K | HOH312 |
site_id | AD3 |
Number of Residues | 7 |
Details | binding site for residue SO4 L 301 |
Chain | Residue |
F | ASN236 |
L | ASN236 |
L | HOH401 |
L | HOH402 |
L | HOH411 |
L | HOH446 |
L | HOH449 |
site_id | AD4 |
Number of Residues | 7 |
Details | binding site for residue SO4 L 302 |
Chain | Residue |
C | TRP172 |
C | LYS175 |
C | SO4302 |
C | HOH434 |
L | TRP172 |
L | SER218 |
L | HOH403 |
Functional Information from PROSITE/UniProt
site_id | PS00134 |
Number of Residues | 6 |
Details | TRYPSIN_HIS Serine proteases, trypsin family, histidine active site. VTAAHC |
Chain | Residue | Details |
B | VAL53-CYS58 | |
site_id | PS00135 |
Number of Residues | 12 |
Details | TRYPSIN_SER Serine proteases, trypsin family, serine active site. SScmGDSGGPLV |
Chain | Residue | Details |
C | SER189-VAL200 | |
Functional Information from SwissProt/UniProt
site_id | SWS_FT_FI1 |
Number of Residues | 4 |
Details | ACT_SITE: Charge relay system |
Chain | Residue | Details |
C | SER195 | |
F | SER195 | |
I | SER195 | |
L | SER195 | |
H | HIS57 | |
H | ASP102 | |
K | HIS57 | |
K | ASP102 | |
Catalytic Information from CSA
site_id | MCSA1 |
Number of Residues | 3 |
Details | M-CSA 387 |
Chain | Residue | Details |
C | GLY193 | electrostatic stabiliser |
C | SER195 | covalent catalysis |
C | GLY196 | electrostatic stabiliser |
site_id | MCSA2 |
Number of Residues | 3 |
Details | M-CSA 387 |
Chain | Residue | Details |
F | GLY193 | electrostatic stabiliser |
F | SER195 | covalent catalysis |
F | GLY196 | electrostatic stabiliser |
site_id | MCSA3 |
Number of Residues | 3 |
Details | M-CSA 387 |
Chain | Residue | Details |
I | GLY193 | electrostatic stabiliser |
I | SER195 | covalent catalysis |
I | GLY196 | electrostatic stabiliser |
site_id | MCSA4 |
Number of Residues | 3 |
Details | M-CSA 387 |
Chain | Residue | Details |
L | GLY193 | electrostatic stabiliser |
L | SER195 | covalent catalysis |
L | GLY196 | electrostatic stabiliser |