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6DGZ

Crystal structure of HIV-1 Protease NL4-3 WT in complex with UMass6

Functional Information from GO Data
ChainGOidnamespacecontents
A0004190molecular_functionaspartic-type endopeptidase activity
A0006508biological_processproteolysis
A0008233molecular_functionpeptidase activity
A0016787molecular_functionhydrolase activity
B0004190molecular_functionaspartic-type endopeptidase activity
B0006508biological_processproteolysis
B0008233molecular_functionpeptidase activity
B0016787molecular_functionhydrolase activity
Functional Information from PDB Data
site_idAC1
Number of Residues4
Detailsbinding site for residue SO4 A 101
ChainResidue
AMET36
AASN37
BPRO39
BGLY40

site_idAC2
Number of Residues17
Detailsbinding site for residue A60 A 102
ChainResidue
AGLY48
AGLY49
AILE50
AHOH207
AHOH229
BASP25
BGLY27
BALA28
BASP30
BGLY48
BGLY49
BPRO81
AASP25
AGLY27
AALA28
AASP29
AASP30

Functional Information from PROSITE/UniProt
site_idPS00141
Number of Residues12
DetailsASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVL
ChainResidueDetails
BALA22-LEU33

218853

PDB entries from 2024-04-24

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