6DGS

Crystal Structure of Leishmania major dihydroorotate dehydrogenase mutant Y142A

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0004152	molecular_function	dihydroorotate dehydrogenase activity
A	0005654	cellular_component	nucleoplasm
A	0005737	cellular_component	cytoplasm
A	0006106	biological_process	fumarate metabolic process
A	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
A	0006221	biological_process	pyrimidine nucleotide biosynthetic process
A	0006222	biological_process	UMP biosynthetic process
A	0016491	molecular_function	oxidoreductase activity
A	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
A	0044205	biological_process	'de novo' UMP biosynthetic process
A	0097014	cellular_component	ciliary plasm
A	1990663	molecular_function	dihydroorotate dehydrogenase (fumarate) activity
B	0000166	molecular_function	nucleotide binding
B	0004152	molecular_function	dihydroorotate dehydrogenase activity
B	0005654	cellular_component	nucleoplasm
B	0005737	cellular_component	cytoplasm
B	0006106	biological_process	fumarate metabolic process
B	0006207	biological_process	'de novo' pyrimidine nucleobase biosynthetic process
B	0006221	biological_process	pyrimidine nucleotide biosynthetic process
B	0006222	biological_process	UMP biosynthetic process
B	0016491	molecular_function	oxidoreductase activity
B	0016627	molecular_function	oxidoreductase activity, acting on the CH-CH group of donors
B	0044205	biological_process	'de novo' UMP biosynthetic process
B	0097014	cellular_component	ciliary plasm
B	1990663	molecular_function	dihydroorotate dehydrogenase (fumarate) activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	25
Details	binding site for residue FMN A 401

site_id	AC2
Number of Residues	7
Details	binding site for residue GOL A 402

site_id	AC4
Number of Residues	24
Details	binding site for residue FMN B 401

site_id	AC5
Number of Residues	7
Details	binding site for residue GOL B 402