6DFK
Crystal structure of the 11S subunit of the Plasmodium falciparum proteasome, PA28
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000502 | cellular_component | proteasome complex |
| A | 0005654 | cellular_component | nucleoplasm |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0008537 | cellular_component | proteasome activator complex |
| A | 0061133 | molecular_function | endopeptidase activator activity |
| A | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| A | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| B | 0000502 | cellular_component | proteasome complex |
| B | 0005654 | cellular_component | nucleoplasm |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0008537 | cellular_component | proteasome activator complex |
| B | 0061133 | molecular_function | endopeptidase activator activity |
| B | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| B | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| C | 0000502 | cellular_component | proteasome complex |
| C | 0005654 | cellular_component | nucleoplasm |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0008537 | cellular_component | proteasome activator complex |
| C | 0061133 | molecular_function | endopeptidase activator activity |
| C | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| C | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| D | 0000502 | cellular_component | proteasome complex |
| D | 0005654 | cellular_component | nucleoplasm |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0008537 | cellular_component | proteasome activator complex |
| D | 0061133 | molecular_function | endopeptidase activator activity |
| D | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| D | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| E | 0000502 | cellular_component | proteasome complex |
| E | 0005654 | cellular_component | nucleoplasm |
| E | 0005737 | cellular_component | cytoplasm |
| E | 0008537 | cellular_component | proteasome activator complex |
| E | 0061133 | molecular_function | endopeptidase activator activity |
| E | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| E | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| F | 0000502 | cellular_component | proteasome complex |
| F | 0005654 | cellular_component | nucleoplasm |
| F | 0005737 | cellular_component | cytoplasm |
| F | 0008537 | cellular_component | proteasome activator complex |
| F | 0061133 | molecular_function | endopeptidase activator activity |
| F | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| F | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| G | 0000502 | cellular_component | proteasome complex |
| G | 0005654 | cellular_component | nucleoplasm |
| G | 0005737 | cellular_component | cytoplasm |
| G | 0008537 | cellular_component | proteasome activator complex |
| G | 0061133 | molecular_function | endopeptidase activator activity |
| G | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| G | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| H | 0000502 | cellular_component | proteasome complex |
| H | 0005654 | cellular_component | nucleoplasm |
| H | 0005737 | cellular_component | cytoplasm |
| H | 0008537 | cellular_component | proteasome activator complex |
| H | 0061133 | molecular_function | endopeptidase activator activity |
| H | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| H | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| I | 0000502 | cellular_component | proteasome complex |
| I | 0005654 | cellular_component | nucleoplasm |
| I | 0005737 | cellular_component | cytoplasm |
| I | 0008537 | cellular_component | proteasome activator complex |
| I | 0061133 | molecular_function | endopeptidase activator activity |
| I | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| I | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| J | 0000502 | cellular_component | proteasome complex |
| J | 0005654 | cellular_component | nucleoplasm |
| J | 0005737 | cellular_component | cytoplasm |
| J | 0008537 | cellular_component | proteasome activator complex |
| J | 0061133 | molecular_function | endopeptidase activator activity |
| J | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| J | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| K | 0000502 | cellular_component | proteasome complex |
| K | 0005654 | cellular_component | nucleoplasm |
| K | 0005737 | cellular_component | cytoplasm |
| K | 0008537 | cellular_component | proteasome activator complex |
| K | 0061133 | molecular_function | endopeptidase activator activity |
| K | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| K | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| L | 0000502 | cellular_component | proteasome complex |
| L | 0005654 | cellular_component | nucleoplasm |
| L | 0005737 | cellular_component | cytoplasm |
| L | 0008537 | cellular_component | proteasome activator complex |
| L | 0061133 | molecular_function | endopeptidase activator activity |
| L | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| L | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| M | 0000502 | cellular_component | proteasome complex |
| M | 0005654 | cellular_component | nucleoplasm |
| M | 0005737 | cellular_component | cytoplasm |
| M | 0008537 | cellular_component | proteasome activator complex |
| M | 0061133 | molecular_function | endopeptidase activator activity |
| M | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| M | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
| N | 0000502 | cellular_component | proteasome complex |
| N | 0005654 | cellular_component | nucleoplasm |
| N | 0005737 | cellular_component | cytoplasm |
| N | 0008537 | cellular_component | proteasome activator complex |
| N | 0061133 | molecular_function | endopeptidase activator activity |
| N | 0061136 | biological_process | regulation of proteasomal protein catabolic process |
| N | 2000045 | biological_process | regulation of G1/S transition of mitotic cell cycle |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 301 |
| Chain | Residue |
| A | ARG44 |
| site_id | AC2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 A 302 |
| Chain | Residue |
| A | LYS215 |
| A | SO4303 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue SO4 A 303 |
| Chain | Residue |
| A | LYS215 |
| A | LYS218 |
| A | TYR219 |
| A | SO4302 |
| B | LYS218 |
| B | SO4304 |
| site_id | AC4 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 A 304 |
| Chain | Residue |
| A | SER194 |
| site_id | AC5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 301 |
| Chain | Residue |
| B | ARG40 |
| B | LYS43 |
| B | ARG44 |
| site_id | AC6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 302 |
| Chain | Residue |
| B | LYS211 |
| B | LYS215 |
| C | LYS211 |
| site_id | AC7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 B 303 |
| Chain | Residue |
| B | LYS215 |
| B | LYS218 |
| B | TYR219 |
| site_id | AC8 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 B 304 |
| Chain | Residue |
| A | LYS218 |
| A | SO4303 |
| B | TYR128 |
| B | LYS218 |
| site_id | AC9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 B 305 |
| Chain | Residue |
| B | SER194 |
| B | ASN197 |
| site_id | AD1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 301 |
| Chain | Residue |
| C | LYS211 |
| C | LYS215 |
| site_id | AD2 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 C 302 |
| Chain | Residue |
| C | LYS215 |
| C | LYS218 |
| C | TYR219 |
| D | LYS218 |
| site_id | AD3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 C 303 |
| Chain | Residue |
| C | LYS218 |
| D | TYR128 |
| D | LYS218 |
| site_id | AD4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 C 304 |
| Chain | Residue |
| C | SER194 |
| C | ASN197 |
| site_id | AD5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 301 |
| Chain | Residue |
| D | LYS43 |
| D | ARG44 |
| site_id | AD6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 D 302 |
| Chain | Residue |
| D | LYS215 |
| D | SO4303 |
| E | LYS211 |
| site_id | AD7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 D 303 |
| Chain | Residue |
| D | LYS215 |
| D | LYS218 |
| D | TYR219 |
| D | SO4302 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 D 304 |
| Chain | Residue |
| D | SER194 |
| D | ASN197 |
| site_id | AD9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 E 301 |
| Chain | Residue |
| D | GLU57 |
| E | ARG40 |
| E | LYS43 |
| E | ARG44 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 E 302 |
| Chain | Residue |
| E | LYS211 |
| E | LYS215 |
| F | LYS211 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 E 303 |
| Chain | Residue |
| E | LYS215 |
| E | LYS218 |
| E | TYR219 |
| F | LYS218 |
| F | SO4304 |
| site_id | AE3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 E 304 |
| Chain | Residue |
| E | SER194 |
| E | ASN197 |
| site_id | AE4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 F 301 |
| Chain | Residue |
| E | GLU57 |
| F | ARG40 |
| F | LYS43 |
| F | ARG44 |
| site_id | AE5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 302 |
| Chain | Residue |
| F | LYS211 |
| F | LYS215 |
| G | LYS211 |
| site_id | AE6 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 F 303 |
| Chain | Residue |
| F | LYS215 |
| F | LYS218 |
| F | TYR219 |
| site_id | AE7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 F 304 |
| Chain | Residue |
| E | LYS218 |
| E | SO4303 |
| F | TYR128 |
| F | LYS218 |
| site_id | AE8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 F 305 |
| Chain | Residue |
| F | SER194 |
| F | ASN197 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 G 301 |
| Chain | Residue |
| F | GLU57 |
| G | ARG40 |
| G | LYS43 |
| G | ARG44 |
| site_id | AF1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 G 302 |
| Chain | Residue |
| G | LYS211 |
| G | LYS215 |
| site_id | AF2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 G 303 |
| Chain | Residue |
| G | LYS215 |
| G | LYS218 |
| G | TYR219 |
| site_id | AF3 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 G 304 |
| Chain | Residue |
| G | SER194 |
| G | ASN197 |
| site_id | AF4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 H 301 |
| Chain | Residue |
| H | LYS211 |
| H | LYS215 |
| site_id | AF5 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 H 302 |
| Chain | Residue |
| H | LYS215 |
| H | LYS218 |
| H | TYR219 |
| I | LYS218 |
| site_id | AF6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 H 303 |
| Chain | Residue |
| H | SER194 |
| H | ASN197 |
| site_id | AF7 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 I 301 |
| Chain | Residue |
| I | ARG40 |
| I | LYS43 |
| I | ARG44 |
| site_id | AF8 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 I 302 |
| Chain | Residue |
| I | LYS211 |
| I | LYS215 |
| site_id | AF9 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 I 303 |
| Chain | Residue |
| I | LYS215 |
| I | LYS218 |
| I | TYR219 |
| site_id | AG1 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 I 304 |
| Chain | Residue |
| I | TYR128 |
| I | LYS218 |
| site_id | AG2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 I 305 |
| Chain | Residue |
| I | SER194 |
| I | ASN197 |
| site_id | AG3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 J 301 |
| Chain | Residue |
| I | PRO58 |
| J | LYS43 |
| J | ARG44 |
| site_id | AG4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 J 302 |
| Chain | Residue |
| J | LYS215 |
| K | LYS211 |
| site_id | AG5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 J 303 |
| Chain | Residue |
| J | LYS215 |
| J | LYS218 |
| J | TYR219 |
| site_id | AG6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 J 304 |
| Chain | Residue |
| J | SER194 |
| J | ASN197 |
| site_id | AG7 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 J 305 |
| Chain | Residue |
| J | LYS211 |
| site_id | AG8 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 K 301 |
| Chain | Residue |
| K | ARG40 |
| K | LYS43 |
| K | ARG44 |
| site_id | AG9 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 K 302 |
| Chain | Residue |
| K | LYS211 |
| K | LYS215 |
| site_id | AH1 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 K 303 |
| Chain | Residue |
| K | LYS215 |
| K | LYS218 |
| K | TYR219 |
| L | LYS218 |
| site_id | AH2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 K 304 |
| Chain | Residue |
| K | SER194 |
| K | ASN197 |
| site_id | AH3 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 L 301 |
| Chain | Residue |
| K | PRO58 |
| L | ARG40 |
| L | LYS43 |
| L | ARG44 |
| site_id | AH4 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 L 302 |
| Chain | Residue |
| L | LYS215 |
| site_id | AH5 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 L 303 |
| Chain | Residue |
| L | LYS215 |
| L | TYR219 |
| site_id | AH6 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 L 304 |
| Chain | Residue |
| L | SER194 |
| L | ASN197 |
| site_id | AH7 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 M 301 |
| Chain | Residue |
| L | PRO58 |
| M | ARG40 |
| M | LYS43 |
| M | ARG44 |
| site_id | AH8 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 M 302 |
| Chain | Residue |
| M | LYS215 |
| site_id | AH9 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 M 303 |
| Chain | Residue |
| M | LYS215 |
| M | LYS218 |
| M | TYR219 |
| N | THR214 |
| N | LYS218 |
| site_id | AI1 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 M 304 |
| Chain | Residue |
| M | LYS218 |
| N | TYR128 |
| N | LYS218 |
| site_id | AI2 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 M 305 |
| Chain | Residue |
| M | SER194 |
| M | ASN197 |
| site_id | AI3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 N 301 |
| Chain | Residue |
| M | GLU57 |
| N | LYS43 |
| N | ARG44 |
| site_id | AI4 |
| Number of Residues | 2 |
| Details | binding site for residue SO4 N 302 |
| Chain | Residue |
| N | LYS211 |
| N | LYS215 |
| site_id | AI5 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 N 303 |
| Chain | Residue |
| N | LYS215 |
| N | LYS218 |
| N | TYR219 |
| site_id | AI6 |
| Number of Residues | 1 |
| Details | binding site for residue SO4 N 304 |
| Chain | Residue |
| N | ASN197 |
