6DE9

mitoNEET bound to furosemide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0010506	biological_process	regulation of autophagy
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue FES A 201

Chain	Residue
A	CYS72
A	ARG73
A	CYS74
A	CYS83
A	ASP84
A	GLY85
A	ALA86
A	HIS87

---

site_id	AC2
Number of Residues	7
Details	binding site for residue FUN A 202

Chain	Residue
A	LYS55
A	LYS55
A	VAL70
A	HIS87
A	ILE102
A	HOH301
A	PRO54

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	76
Details	TOPO_DOM: Cytoplasmic => ECO:0000255

Chain	Residue	Details
A	LYS32-THR108

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Schiff-base intermediate with pyridoxal 5'-phosphate => ECO:0000269|PubMed:36194135

Chain	Residue	Details
A	LYS55

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site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:17766439, ECO:0000269|PubMed:17766440, ECO:0000269|PubMed:17905743, ECO:0007744|PDB:2QD0, ECO:0007744|PDB:2QH7, ECO:0007744|PDB:2R13

Chain	Residue	Details
A	CYS72
A	CYS74
A	CYS83
A	HIS87

---

site_id	SWS_FT_FI4
Number of Residues	3
Details	MOD_RES: N6-acetyllysine; alternate => ECO:0000250|UniProtKB:Q91WS0

Chain	Residue	Details
A	LYS55
A	LYS68
A	LYS104

---

site_id	SWS_FT_FI5
Number of Residues	7
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin) => ECO:0000269|PubMed:25621951

Chain	Residue	Details
A	LYS42
A	LYS78
A	LYS79
A	LYS89
A	LYS105
A	LYS106

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site_id	SWS_FT_FI6
Number of Residues	3
Details	CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate => ECO:0000269|PubMed:25621951

Chain	Residue	Details
A	LYS55
A	LYS68
A	LYS104

---