6DE9

mitoNEET bound to furosemide

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0010506	biological_process	regulation of autophagy
A	0043231	cellular_component	intracellular membrane-bounded organelle
A	0051537	molecular_function	2 iron, 2 sulfur cluster binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue FES A 201

Chain	Residue
A	CYS72
A	ARG73
A	CYS74
A	CYS83
A	ASP84
A	GLY85
A	ALA86
A	HIS87

---

site_id	AC2
Number of Residues	7
Details	binding site for residue FUN A 202

Chain	Residue
A	LYS55
A	LYS55
A	VAL70
A	HIS87
A	ILE102
A	HOH301
A	PRO54

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Schiff-base intermediate with pyridoxal 5'-phosphate","evidences":[{"source":"PubMed","id":"36194135","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	4
Details	Binding site: {"evidences":[{"source":"PubMed","id":"17766439","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17766440","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"17905743","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"2QD0","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2QH7","evidenceCode":"ECO:0007744"},{"source":"PDB","id":"2R13","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	3
Details	Modified residue: {"description":"N6-acetyllysine; alternate","evidences":[{"source":"UniProtKB","id":"Q91WS0","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin)","evidences":[{"source":"PubMed","id":"25621951","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	3
Details	Cross-link: {"description":"Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in ubiquitin); alternate","evidences":[{"source":"PubMed","id":"25621951","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

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