6DE5

Mycobacterium tuberculosis Rv2671 complexed with beta-NADPH and 6-ethyl-5-{(3S)-3-[2-methoxy-5-(pyridin-4-yl)phenyl]but-1-yn-1-yl}pyrimidine-2,4-diamine

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005829	cellular_component	cytosol
A	0008703	molecular_function	5-amino-6-(5-phosphoribosylamino)uracil reductase activity
A	0009231	biological_process	riboflavin biosynthetic process
A	0016491	molecular_function	oxidoreductase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	22
Details	binding site for residue NDP A 301

Chain	Residue
A	PHE45
A	VAL120
A	THR121
A	ARG122
A	SER123
A	GLU175
A	GLY195
A	PRO196
A	THR197
A	LEU198
A	THR201
A	ALA53
A	ARG225
A	HOH401
A	HOH433
A	THR54
A	GLY57
A	SER59
A	GLY84
A	VAL85
A	GLY86
A	THR87

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site_id	AC2
Number of Residues	9
Details	binding site for residue G8J A 302

Chain	Residue
A	ASN44
A	PHE45
A	ILE46
A	SER59
A	ASP67
A	ARG68
A	PHE71
A	GLU193
A	THR214

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