6DCB
Structure of methylphosphate capping enzyme methyltransferase domain in complex with 5' end of 7SK RNA
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0008168 | molecular_function | methyltransferase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 20 |
| Details | binding site for residue SAH A 701 |
| Chain | Residue |
| A | TYR415 |
| A | ILE475 |
| A | LEU479 |
| A | GLY558 |
| A | ASN559 |
| A | TYR560 |
| A | LEU581 |
| A | SER582 |
| A | LEU583 |
| A | TRP591 |
| A | HOH871 |
| A | GLY416 |
| B | GTP1 |
| A | ASN417 |
| A | TYR421 |
| A | TYR422 |
| A | ARG433 |
| A | GLY451 |
| A | ASN453 |
| A | ASP474 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 702 |
| Chain | Residue |
| A | ILE480 |
| A | ARG484 |
| A | THR557 |
| A | ARG639 |
| A | HOH874 |
| site_id | AC3 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 703 |
| Chain | Residue |
| A | THR557 |
| A | ARG639 |
| A | HOH859 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue SO4 A 704 |
| Chain | Residue |
| A | GLN571 |
| A | GLU574 |
| A | ARG602 |
| A | HIS606 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:30559425, ECO:0007744|PDB:6DCB, ECO:0007744|PDB:6DCC |
| Chain | Residue | Details |
| A | TYR422 | |
| A | ARG433 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | BINDING: BINDING => ECO:0000269|PubMed:30559425, ECO:0000269|Ref.26, ECO:0007744|PDB:5UNA, ECO:0007744|PDB:6DCB, ECO:0007744|PDB:6DCC |
| Chain | Residue | Details |
| A | ASP474 | |
| A | ASN559 | |
| A | LEU581 | |
| A | GLY451 |
| site_id | SWS_FT_FI3 |
| Number of Residues | 2 |
| Details | CROSSLNK: Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2) => ECO:0007744|PubMed:28112733 |
| Chain | Residue | Details |
| A | LYS643 |
