6DBB
Crystal structure of a Putative aldehyde dehydrogenase family protein Burkholderia cenocepacia J2315 in complex with partially reduced NADH
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| B | 0016491 | molecular_function | oxidoreductase activity |
| B | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0004029 | molecular_function | aldehyde dehydrogenase (NAD+) activity |
| C | 0016491 | molecular_function | oxidoreductase activity |
| C | 0016620 | molecular_function | oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 31 |
| Details | binding site for residue NAD A 601 |
| Chain | Residue |
| A | ILE147 |
| A | THR235 |
| A | GLY236 |
| A | SER237 |
| A | MET240 |
| A | GLU258 |
| A | LEU259 |
| A | GLY260 |
| A | GLY261 |
| A | CYS292 |
| A | GLU390 |
| A | SER148 |
| A | PHE392 |
| A | PHE459 |
| A | NAX602 |
| A | EDO605 |
| A | HOH701 |
| A | HOH708 |
| A | HOH724 |
| A | HOH737 |
| A | HOH777 |
| A | HOH861 |
| A | ALA149 |
| A | HOH988 |
| A | HOH998 |
| A | PHE150 |
| A | ASN151 |
| A | LYS174 |
| A | SER176 |
| A | GLU177 |
| A | ARG217 |
| site_id | AC2 |
| Number of Residues | 31 |
| Details | binding site for residue NAX A 602 |
| Chain | Residue |
| A | ILE147 |
| A | SER148 |
| A | ALA149 |
| A | PHE150 |
| A | ASN151 |
| A | LYS174 |
| A | SER176 |
| A | GLU177 |
| A | ARG217 |
| A | THR235 |
| A | GLY236 |
| A | SER237 |
| A | MET240 |
| A | GLU258 |
| A | LEU259 |
| A | GLY260 |
| A | GLY261 |
| A | CYS292 |
| A | GLU390 |
| A | PHE392 |
| A | PHE459 |
| A | NAD601 |
| A | EDO605 |
| A | HOH701 |
| A | HOH708 |
| A | HOH724 |
| A | HOH737 |
| A | HOH777 |
| A | HOH861 |
| A | HOH988 |
| A | HOH998 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 603 |
| Chain | Residue |
| A | LEU120 |
| A | ALA126 |
| A | TRP138 |
| A | HOH792 |
| A | HOH810 |
| A | HOH850 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 604 |
| Chain | Residue |
| A | ILE141 |
| A | GLU462 |
| A | LYS463 |
| A | ARG481 |
| A | HOH713 |
| A | HOH870 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 605 |
| Chain | Residue |
| A | GLU221 |
| A | THR224 |
| A | GLU243 |
| A | VAL247 |
| A | NAD601 |
| A | NAX602 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 606 |
| Chain | Residue |
| A | ASP39 |
| A | LYS47 |
| A | LEU212 |
| A | LEU214 |
| A | HOH824 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 607 |
| Chain | Residue |
| A | SER318 |
| A | VAL319 |
| A | LYS320 |
| A | GLY328 |
| A | LEU330 |
| A | GLN497 |
| A | GLY498 |
| site_id | AC8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 608 |
| Chain | Residue |
| A | GLU313 |
| A | ALA317 |
| A | GLY359 |
| A | HOH735 |
| A | HOH838 |
| site_id | AC9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 609 |
| Chain | Residue |
| A | VAL156 |
| A | TRP159 |
| A | EDO610 |
| A | GLU105 |
| A | PHE152 |
| site_id | AD1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 610 |
| Chain | Residue |
| A | PHE152 |
| A | ARG291 |
| A | CYS292 |
| A | THR293 |
| A | EDO609 |
| A | HOH718 |
| A | HOH908 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 611 |
| Chain | Residue |
| A | HIS187 |
| A | GLN191 |
| A | ALA207 |
| A | GLU208 |
| A | GLY210 |
| A | HOH951 |
| site_id | AD3 |
| Number of Residues | 32 |
| Details | binding site for residue NAD B 601 |
| Chain | Residue |
| B | ILE147 |
| B | SER148 |
| B | ALA149 |
| B | PHE150 |
| B | ASN151 |
| B | LYS174 |
| B | PRO175 |
| B | SER176 |
| B | GLU177 |
| B | ARG217 |
| B | THR235 |
| B | GLY236 |
| B | SER237 |
| B | MET240 |
| B | GLU258 |
| B | LEU259 |
| B | GLY260 |
| B | GLY261 |
| B | CYS292 |
| B | GLU390 |
| B | PHE392 |
| B | PHE459 |
| B | NAX602 |
| B | EDO605 |
| B | HOH705 |
| B | HOH715 |
| B | HOH752 |
| B | HOH757 |
| B | HOH780 |
| B | HOH880 |
| B | HOH987 |
| B | HOH1014 |
| site_id | AD4 |
| Number of Residues | 32 |
| Details | binding site for residue NAX B 602 |
| Chain | Residue |
| B | ILE147 |
| B | SER148 |
| B | ALA149 |
| B | PHE150 |
| B | ASN151 |
| B | LYS174 |
| B | PRO175 |
| B | SER176 |
| B | GLU177 |
| B | ARG217 |
| B | THR235 |
| B | GLY236 |
| B | SER237 |
| B | MET240 |
| B | GLU258 |
| B | LEU259 |
| B | GLY260 |
| B | GLY261 |
| B | CYS292 |
| B | GLU390 |
| B | PHE392 |
| B | PHE459 |
| B | NAD601 |
| B | EDO605 |
| B | HOH705 |
| B | HOH715 |
| B | HOH752 |
| B | HOH757 |
| B | HOH780 |
| B | HOH880 |
| B | HOH987 |
| B | HOH1014 |
| site_id | AD5 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 603 |
| Chain | Residue |
| B | LEU120 |
| B | TRP138 |
| B | HOH754 |
| B | HOH758 |
| B | HOH858 |
| C | ALA126 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 604 |
| Chain | Residue |
| B | ILE141 |
| B | GLU462 |
| B | LYS463 |
| B | ARG481 |
| B | HOH777 |
| B | HOH863 |
| B | HOH892 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 605 |
| Chain | Residue |
| B | GLU221 |
| B | THR224 |
| B | GLU243 |
| B | VAL247 |
| B | NAD601 |
| B | NAX602 |
| B | HOH938 |
| site_id | AD8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 606 |
| Chain | Residue |
| B | ASP39 |
| B | LYS47 |
| B | LEU212 |
| B | HOH781 |
| B | HOH1011 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 607 |
| Chain | Residue |
| B | SER318 |
| B | LYS320 |
| B | GLY328 |
| B | LEU330 |
| B | GLY498 |
| B | HOH825 |
| site_id | AE1 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 608 |
| Chain | Residue |
| B | GLU313 |
| B | GLY359 |
| B | HOH764 |
| B | HOH978 |
| B | HOH1016 |
| site_id | AE2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 609 |
| Chain | Residue |
| B | GLU105 |
| B | PHE152 |
| B | VAL156 |
| B | TRP159 |
| B | EDO610 |
| site_id | AE3 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 610 |
| Chain | Residue |
| B | PHE152 |
| B | CYS292 |
| B | THR293 |
| B | EDO609 |
| site_id | AE4 |
| Number of Residues | 28 |
| Details | binding site for residue NAD C 601 |
| Chain | Residue |
| C | ILE147 |
| C | SER148 |
| C | ALA149 |
| C | PHE150 |
| C | ASN151 |
| C | LYS174 |
| C | PRO175 |
| C | SER176 |
| C | GLU177 |
| C | GLY220 |
| C | GLU221 |
| C | THR235 |
| C | GLY236 |
| C | SER237 |
| C | MET240 |
| C | GLU243 |
| C | GLU258 |
| C | LEU259 |
| C | GLY260 |
| C | CYS292 |
| C | GLU390 |
| C | PHE392 |
| C | PHE459 |
| C | NAX602 |
| C | HOH714 |
| C | HOH753 |
| C | HOH863 |
| C | HOH882 |
| site_id | AE5 |
| Number of Residues | 28 |
| Details | binding site for residue NAX C 602 |
| Chain | Residue |
| C | ILE147 |
| C | SER148 |
| C | ALA149 |
| C | PHE150 |
| C | ASN151 |
| C | LYS174 |
| C | PRO175 |
| C | SER176 |
| C | GLU177 |
| C | GLY220 |
| C | GLU221 |
| C | THR235 |
| C | GLY236 |
| C | SER237 |
| C | MET240 |
| C | GLU243 |
| C | GLU258 |
| C | LEU259 |
| C | GLY260 |
| C | CYS292 |
| C | GLU390 |
| C | PHE392 |
| C | PHE459 |
| C | NAD601 |
| C | HOH714 |
| C | HOH753 |
| C | HOH863 |
| C | HOH882 |
| site_id | AE6 |
| Number of Residues | 6 |
| Details | binding site for residue EDO C 603 |
| Chain | Residue |
| B | ALA126 |
| C | LEU120 |
| C | TRP138 |
| C | HOH777 |
| C | HOH817 |
| C | HOH832 |
| site_id | AE7 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 604 |
| Chain | Residue |
| C | ILE141 |
| C | GLU462 |
| C | LYS463 |
| C | ARG481 |
| C | HOH750 |
| site_id | AE8 |
| Number of Residues | 5 |
| Details | binding site for residue EDO C 605 |
| Chain | Residue |
| C | SER318 |
| C | LYS320 |
| C | GLY328 |
| C | GLN497 |
| C | GLY498 |
| site_id | AE9 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 606 |
| Chain | Residue |
| C | GLU313 |
| C | LYS358 |
| C | GLY359 |
| C | HOH791 |
| site_id | AF1 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 607 |
| Chain | Residue |
| C | GLU105 |
| C | TRP159 |
| C | EDO608 |
| site_id | AF2 |
| Number of Residues | 4 |
| Details | binding site for residue EDO C 608 |
| Chain | Residue |
| C | PHE152 |
| C | CYS292 |
| C | THR293 |
| C | EDO607 |
| site_id | AF3 |
| Number of Residues | 3 |
| Details | binding site for residue EDO C 609 |
| Chain | Residue |
| C | HIS187 |
| C | GLN191 |
| C | GLU208 |
