Summary Structural details Experimental details Functional details Sequence Neighbor History Downloads

6DAY

Xanthomonas albilineans Dihydropteroate synthase with 4-aminobenzoic acid at 1.65 A

Replaces: 5UUR

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004156	molecular_function	dihydropteroate synthase activity
A	0005829	cellular_component	cytosol
A	0009396	biological_process	folic acid-containing compound biosynthetic process
A	0016740	molecular_function	transferase activity
A	0042558	biological_process	pteridine-containing compound metabolic process
A	0044237	biological_process	cellular metabolic process
A	0046654	biological_process	tetrahydrofolate biosynthetic process
A	0046656	biological_process	folic acid biosynthetic process
A	0046872	molecular_function	metal ion binding
B	0004156	molecular_function	dihydropteroate synthase activity
B	0005829	cellular_component	cytosol
B	0009396	biological_process	folic acid-containing compound biosynthetic process
B	0016740	molecular_function	transferase activity
B	0042558	biological_process	pteridine-containing compound metabolic process
B	0044237	biological_process	cellular metabolic process
B	0046654	biological_process	tetrahydrofolate biosynthetic process
B	0046656	biological_process	folic acid biosynthetic process
B	0046872	molecular_function	metal ion binding
C	0004156	molecular_function	dihydropteroate synthase activity
C	0005829	cellular_component	cytosol
C	0009396	biological_process	folic acid-containing compound biosynthetic process
C	0016740	molecular_function	transferase activity
C	0042558	biological_process	pteridine-containing compound metabolic process
C	0044237	biological_process	cellular metabolic process
C	0046654	biological_process	tetrahydrofolate biosynthetic process
C	0046656	biological_process	folic acid biosynthetic process
C	0046872	molecular_function	metal ion binding
D	0004156	molecular_function	dihydropteroate synthase activity
D	0005829	cellular_component	cytosol
D	0009396	biological_process	folic acid-containing compound biosynthetic process
D	0016740	molecular_function	transferase activity
D	0042558	biological_process	pteridine-containing compound metabolic process
D	0044237	biological_process	cellular metabolic process
D	0046654	biological_process	tetrahydrofolate biosynthetic process
D	0046656	biological_process	folic acid biosynthetic process
D	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue PAB A 401

Chain	Residue
A	ALA243
D	GLY36
D	GLY37
A	VAL246
A	ALA267
A	HOH597
B	VAL242
B	ALA243
B	VAL246
B	HOH527
D	SER34

site_id	AC2
Number of Residues	6
Details	binding site for residue PAB A 402

Chain	Residue
A	HIS48
A	HOH562
D	THR72
D	ALA73
D	PRO75
D	ARG82

site_id	AC3
Number of Residues	5
Details	binding site for residue SO4 A 403

Chain	Residue
A	ILE25
A	ASN27
A	ARG261
A	HIS263
A	HOH519

site_id	AC4
Number of Residues	6
Details	binding site for residue SO4 A 404

Chain	Residue
A	GLY194
A	PHE195
A	LYS226
A	ARG227
A	HOH501
A	HOH508

site_id	AC5
Number of Residues	8
Details	binding site for residue PAB B 401

Chain	Residue
B	THR67
B	GLY194
B	PHE195
B	LYS226
B	ARG227
B	SO4404
B	SO4405
B	HOH519

site_id	AC6
Number of Residues	6
Details	binding site for residue PAB B 402

Chain	Residue
B	THR72
B	ALA73
B	VAL74
B	ARG82
C	HIS48
C	HOH564

site_id	AC7
Number of Residues	5
Details	binding site for residue PAB B 403

Chain	Residue
B	ALA47
B	HIS48
B	ARG51
B	HOH529
B	HOH531

site_id	AC8
Number of Residues	5
Details	binding site for residue SO4 B 404

Chain	Residue
B	ASN27
B	ARG261
B	HIS263
B	PAB401
B	HOH533

site_id	AC9
Number of Residues	3
Details	binding site for residue SO4 B 405

Chain	Residue
B	ARG227
B	ARG241
B	PAB401

site_id	AD1
Number of Residues	11
Details	binding site for residue PAB C 401

Chain	Residue
B	GLY37
B	HOH566
C	ALA243
C	VAL246
C	ALA267
C	HOH506
C	HOH535
D	VAL242
D	ALA243
D	VAL246
D	HOH582

site_id	AD2
Number of Residues	4
Details	binding site for residue GOL C 402

Chain	Residue
C	ASN27
C	ARG261
C	HIS263
C	HOH593

site_id	AD3
Number of Residues	5
Details	binding site for residue GOL C 403

Chain	Residue
C	ARG19
C	PRO20
C	ASP58
C	THR273
C	HOH545

site_id	AD4
Number of Residues	8
Details	binding site for residue SO4 C 404

Chain	Residue
C	GLY194
C	PHE195
C	LYS226
C	ARG227
C	HOH504
C	HOH507
C	HOH639
C	HOH642

site_id	AD5
Number of Residues	8
Details	binding site for residue PAB D 401

Chain	Residue
D	THR67
D	GLY194
D	PHE195
D	LYS226
D	ARG227
D	SO4404
D	HOH566
D	HOH585

site_id	AD6
Number of Residues	4
Details	binding site for residue GOL D 402

Chain	Residue
D	ARG19
D	PRO20
D	ASP58
D	THR273

site_id	AD7
Number of Residues	6
Details	binding site for residue SO4 D 404

Chain	Residue
D	HOH581
D	HOH610
D	ASN27
D	ARG261
D	HIS263
D	PAB401

site_id	AD8
Number of Residues	10
Details	binding site for Di-peptide PAB D 403 and ARG D 51

Chain	Residue
D	ALA47
D	HIS48
D	GLY49
D	LEU50
D	LEU52
D	ALA53
D	GLU54
D	GLU55
D	HOH543
D	HOH558

Functional Information from PROSITE/UniProt

site_id	PS00792
Number of Residues	16
Details	DHPS_1 Dihydropteroate synthase signature 1. VmGIVNvTpDSFsDgG

Chain	Residue	Details
A	VAL22-GLY37

site_id	PS00793
Number of Residues	14
Details	DHPS_2 Dihydropteroate synthase signature 2. GAdLLDIGGesTrP

Chain	Residue	Details
A	GLY56-PRO69

		Sequence (fasta)
		PDBx/mmCIF
		PDBML format (no-atom)
		PDB format (full)
		Validation report (PDF)
		EDMap 2fo-fc (MTZ)