6DA9

Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes with FMN bound at 2.05 A resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0005829	cellular_component	cytosol
A	0006744	biological_process	ubiquinone biosynthetic process
A	0008694	molecular_function	3-octaprenyl-4-hydroxybenzoate carboxy-lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0019439	biological_process	obsolete aromatic compound catabolic process
A	0033494	biological_process	ferulate metabolic process
A	0046281	biological_process	cinnamic acid catabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	24
Details	binding site for residue FMN A 501

Chain	Residue
A	THR149
A	ALA218
A	SER219
A	MET220
A	PRO221
A	GLU228
A	SER308
A	GLU316
A	TRP321
A	ARG386
A	MN502
A	ASN164
A	GOL512
A	HOH617
A	HOH625
A	HOH659
A	HOH691
A	ALA166
A	ILE167
A	ALA168
A	ARG169
A	ILE183
A	GLN186
A	HIS187

---

site_id	AC2
Number of Residues	6
Details	binding site for residue MN A 502

Chain	Residue
A	ASN164
A	HIS187
A	GLU228
A	FMN501
A	HOH602
A	HOH625

---

site_id	AC3
Number of Residues	7
Details	binding site for residue GOL A 503

Chain	Residue
A	GLY74
A	SER75
A	PRO76
A	LEU77
A	SER89
A	HOH603
A	HOH680

---

site_id	AC4
Number of Residues	4
Details	binding site for residue GOL A 504

Chain	Residue
A	ASP402
A	SER404
A	ASP405
A	HOH680

---

site_id	AC5
Number of Residues	6
Details	binding site for residue GOL A 505

Chain	Residue
A	LEU130
A	ASP131
A	PHE133
A	ALA135
A	LYS172
A	HOH630

---

site_id	AC6
Number of Residues	3
Details	binding site for residue GOL A 506

Chain	Residue
A	VAL122
A	LEU124
A	ASP127

---

site_id	AC7
Number of Residues	4
Details	binding site for residue GOL A 507

Chain	Residue
A	THR163
A	GLU227
A	LEU242
A	HOH639

---

site_id	AC8
Number of Residues	1
Details	binding site for residue GOL A 508

Chain	Residue
A	ARG377

---

site_id	AC9
Number of Residues	5
Details	binding site for residue GOL A 509

Chain	Residue
A	TRP411
A	THR415
A	ARG416
A	LEU456
A	ARG464

---

site_id	AD1
Number of Residues	6
Details	binding site for residue GOL A 510

Chain	Residue
A	TYR41
A	GLU42
A	ARG44
A	PRO313
A	VAL314
A	HOH715

---

site_id	AD2
Number of Residues	5
Details	binding site for residue GOL A 511

Chain	Residue
A	ARG363
A	SER370
A	ARG371
A	HOH646
A	HOH673

---

site_id	AD3
Number of Residues	5
Details	binding site for residue GOL A 512

Chain	Residue
A	GLN186
A	PRO221
A	ARG386
A	MET390
A	FMN501

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