6DA7

Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes with apo form at 1.83 A resolution (I222)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000166	molecular_function	nucleotide binding
A	0005737	cellular_component	cytoplasm
A	0016829	molecular_function	lyase activity
A	0016831	molecular_function	carboxy-lyase activity
A	0033494	biological_process	ferulate metabolic process
A	0034941	molecular_function	pyrrole-2-carboxylate decarboxylase activity
A	0046281	biological_process	cinnamic acid catabolic process
A	0046872	molecular_function	metal ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue NA A 501

Chain	Residue
A	ASN164
A	TRP165
A	HIS187
A	GLU228
A	EPE502
A	HOH623
A	HOH638

---

site_id	AC2
Number of Residues	12
Details	binding site for residue EPE A 502

Chain	Residue
A	GLN186
A	HIS187
A	ALA218
A	SER219
A	TRP321
A	ARG386
A	NA501
A	HOH621
A	HOH623
A	HOH758
A	ILE167
A	ARG169

---

site_id	AC3
Number of Residues	9
Details	binding site for residue GOL A 503

Chain	Residue
A	GLY74
A	SER75
A	PRO76
A	LEU77
A	SER89
A	ALA90
A	GOL505
A	HOH606
A	HOH673

---

site_id	AC4
Number of Residues	8
Details	binding site for residue GOL A 504

Chain	Residue
A	ARG416
A	HIS421
A	GLY435
A	CYS436
A	TYR437
A	LEU456
A	GOL515
A	GOL519

---

site_id	AC5
Number of Residues	3
Details	binding site for residue GOL A 505

Chain	Residue
A	ASP402
A	SER404
A	GOL503

---

site_id	AC6
Number of Residues	5
Details	binding site for residue GOL A 506

Chain	Residue
A	TYR41
A	PRO313
A	VAL314
A	THR407
A	HOH672

---

site_id	AC7
Number of Residues	8
Details	binding site for residue GOL A 507

Chain	Residue
A	GLU360
A	ARG363
A	ASP398
A	LEU456
A	PRO457
A	MET459
A	ARG464
A	HOH730

---

site_id	AC8
Number of Residues	3
Details	binding site for residue GOL A 508

Chain	Residue
A	THR163
A	GLU227
A	HOH685

---

site_id	AC9
Number of Residues	9
Details	binding site for residue GOL A 509

Chain	Residue
A	TRP344
A	PRO346
A	PHE347
A	GLU348
A	SER404
A	GLN406
A	HOH622
A	HOH646
A	HOH738

---

site_id	AD1
Number of Residues	1
Details	binding site for residue GOL A 510

Chain	Residue
A	ARG377

---

site_id	AD2
Number of Residues	4
Details	binding site for residue GOL A 511

Chain	Residue
A	ALA310
A	SER466
A	HOH666
A	HOH768

---

site_id	AD3
Number of Residues	7
Details	binding site for residue GOL A 512

Chain	Residue
A	THR149
A	TRP150
A	ARG169
A	SER219
A	SER308
A	THR317
A	HOH609

---

site_id	AD4
Number of Residues	2
Details	binding site for residue GOL A 513

Chain	Residue
A	SER89
A	GLU94

---

site_id	AD5
Number of Residues	5
Details	binding site for residue GOL A 514

Chain	Residue
A	ARG8
A	GLU15
A	GLU22
A	ARG61
A	HOH765

---

site_id	AD6
Number of Residues	7
Details	binding site for residue GOL A 515

Chain	Residue
A	TRP411
A	THR415
A	ARG416
A	GLY435
A	LEU456
A	ARG464
A	GOL504

---

site_id	AD7
Number of Residues	6
Details	binding site for residue GOL A 516

Chain	Residue
A	ASP372
A	HIS421
A	GLY422
A	ARG423
A	LEU424
A	HOH615

---

site_id	AD8
Number of Residues	7
Details	binding site for residue GOL A 517

Chain	Residue
A	ALA135
A	LYS172
A	HOH640
A	HOH717
A	LEU130
A	ASP131
A	PHE133

---

site_id	AD9
Number of Residues	5
Details	binding site for residue GOL A 518

Chain	Residue
A	ARG363
A	SER370
A	ARG371
A	PRO457
A	HOH762

---

site_id	AE1
Number of Residues	7
Details	binding site for residue GOL A 519

Chain	Residue
A	ARG371
A	ASP372
A	HIS421
A	GLY422
A	GOL504
A	HOH604
A	HOH677

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