6DA6
Crystal structure of the TtnD decarboxylase from the tautomycetin biosynthesis pathway of Streptomyces griseochromogenes, apo form at 2.6 A resolution (P212121)
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016829 | molecular_function | lyase activity |
| A | 0016831 | molecular_function | carboxy-lyase activity |
| A | 0033494 | biological_process | ferulate metabolic process |
| A | 0034941 | molecular_function | pyrrole-2-carboxylate decarboxylase activity |
| A | 0046281 | biological_process | cinnamic acid catabolic process |
| A | 0046872 | molecular_function | metal ion binding |
| B | 0000166 | molecular_function | nucleotide binding |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016829 | molecular_function | lyase activity |
| B | 0016831 | molecular_function | carboxy-lyase activity |
| B | 0033494 | biological_process | ferulate metabolic process |
| B | 0034941 | molecular_function | pyrrole-2-carboxylate decarboxylase activity |
| B | 0046281 | biological_process | cinnamic acid catabolic process |
| B | 0046872 | molecular_function | metal ion binding |
| C | 0000166 | molecular_function | nucleotide binding |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016829 | molecular_function | lyase activity |
| C | 0016831 | molecular_function | carboxy-lyase activity |
| C | 0033494 | biological_process | ferulate metabolic process |
| C | 0034941 | molecular_function | pyrrole-2-carboxylate decarboxylase activity |
| C | 0046281 | biological_process | cinnamic acid catabolic process |
| C | 0046872 | molecular_function | metal ion binding |
| D | 0000166 | molecular_function | nucleotide binding |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016829 | molecular_function | lyase activity |
| D | 0016831 | molecular_function | carboxy-lyase activity |
| D | 0033494 | biological_process | ferulate metabolic process |
| D | 0034941 | molecular_function | pyrrole-2-carboxylate decarboxylase activity |
| D | 0046281 | biological_process | cinnamic acid catabolic process |
| D | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 501 |
| Chain | Residue |
| A | MET220 |
| A | GLU228 |
| A | HOH601 |
| A | HOH625 |
| A | HOH662 |
| A | HOH664 |
| A | HOH666 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue GOL A 502 |
| Chain | Residue |
| A | VAL314 |
| A | HOH658 |
| A | TYR41 |
| A | GLU42 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 503 |
| Chain | Residue |
| A | ARG371 |
| A | ARG416 |
| A | SER418 |
| A | HIS421 |
| C | CYS436 |
| site_id | AC4 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 504 |
| Chain | Residue |
| A | TRP344 |
| A | PRO346 |
| A | PHE347 |
| A | GLU348 |
| A | SER404 |
| A | HOH627 |
| A | HOH638 |
| A | HOH658 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue GOL A 505 |
| Chain | Residue |
| A | THR149 |
| A | ARG169 |
| A | SER219 |
| A | SER308 |
| A | ALA310 |
| A | THR317 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue GOL A 506 |
| Chain | Residue |
| A | ASP87 |
| A | SER89 |
| A | THR91 |
| A | GLU94 |
| A | GOL507 |
| site_id | AC7 |
| Number of Residues | 8 |
| Details | binding site for residue GOL A 507 |
| Chain | Residue |
| A | GLY74 |
| A | SER75 |
| A | PRO76 |
| A | LEU77 |
| A | SER89 |
| A | GOL506 |
| A | HOH605 |
| A | HOH639 |
| site_id | AC8 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 501 |
| Chain | Residue |
| B | GLY74 |
| B | SER75 |
| B | PRO76 |
| B | LEU77 |
| B | SER89 |
| B | ALA90 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL B 502 |
| Chain | Residue |
| B | THR163 |
| B | GLU227 |
| B | VAL229 |
| B | LEU251 |
| B | HOH605 |
| B | HOH613 |
| site_id | AD1 |
| Number of Residues | 3 |
| Details | binding site for residue GOL B 503 |
| Chain | Residue |
| B | GLU348 |
| B | SER404 |
| B | HOH631 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 504 |
| Chain | Residue |
| B | ARG416 |
| B | SER418 |
| B | HIS421 |
| D | GLY435 |
| D | CYS436 |
| site_id | AD3 |
| Number of Residues | 5 |
| Details | binding site for residue GOL B 505 |
| Chain | Residue |
| B | THR149 |
| B | SER219 |
| B | SER308 |
| B | THR317 |
| B | TRP321 |
| site_id | AD4 |
| Number of Residues | 7 |
| Details | binding site for residue MG B 506 |
| Chain | Residue |
| B | MET220 |
| B | GLU228 |
| B | HOH601 |
| B | HOH633 |
| B | HOH650 |
| B | HOH655 |
| B | HOH659 |
| site_id | AD5 |
| Number of Residues | 5 |
| Details | binding site for residue GOL C 501 |
| Chain | Residue |
| C | TYR41 |
| C | GLU42 |
| C | ARG44 |
| C | PRO313 |
| C | VAL314 |
| site_id | AD6 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 502 |
| Chain | Residue |
| C | ARG377 |
| C | GLN380 |
| site_id | AD7 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 503 |
| Chain | Residue |
| C | GLY74 |
| C | SER75 |
| C | PRO76 |
| C | LEU77 |
| C | SER89 |
| C | ALA90 |
| C | HOH607 |
| site_id | AD8 |
| Number of Residues | 2 |
| Details | binding site for residue GOL C 504 |
| Chain | Residue |
| C | ARG169 |
| C | ALA310 |
| site_id | AD9 |
| Number of Residues | 6 |
| Details | binding site for residue GOL D 501 |
| Chain | Residue |
| B | GLY435 |
| B | TYR437 |
| D | ARG371 |
| D | ARG416 |
| D | HIS421 |
| D | LEU455 |
| site_id | AE1 |
| Number of Residues | 3 |
| Details | binding site for residue MG D 503 |
| Chain | Residue |
| D | GLU228 |
| D | ALA218 |
| D | MET220 |
