6D51

Crystal structure of L,D-transpeptidase 3 from Mycobacterium tuberculosis in complex with a faropenem-derived adduct

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0016740	molecular_function	transferase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	3
Details	binding site for residue ACE A 301

Chain	Residue
A	MET164
A	TYR179
A	CYS215

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site_id	AC2
Number of Residues	6
Details	binding site for residue CA A 302

Chain	Residue
A	VAL17
A	ASP231
A	HOH455
A	HOH510
A	HOH518
A	HOH550

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	ACT_SITE: Proton donor/acceptor => ECO:0000255|PROSITE-ProRule:PRU01373

Chain	Residue	Details
A	HIS197

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site_id	SWS_FT_FI2
Number of Residues	1
Details	ACT_SITE: Nucleophile => ECO:0000255|PROSITE-ProRule:PRU01373

Chain	Residue	Details
A	CYS215

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site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Binds to carbapenem drug (covalent) => ECO:0000250

Chain	Residue	Details
A	CYS215

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