Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help

6D4S

M. thermoresistible GuaB2 delta-CBS in complex with inhibitor Compound 37 (VCC670597)

Functional Information from GO Data
ChainGOidnamespacecontents
A0003824molecular_functioncatalytic activity
A0003938molecular_functionIMP dehydrogenase activity
A0006164biological_processpurine nucleotide biosynthetic process
A0016491molecular_functionoxidoreductase activity
Functional Information from PDB Data
site_idAC1
Number of Residues24
Detailsbinding site for residue IMP A 401
ChainResidue
ASER68
AMET255
AGLY257
ASER258
ATYR281
AGLY283
AMET284
AGLY285
AGLU318
AGLY319
AFWV402
AMET70
AHOH516
AHOH548
AHOH569
AHOH617
AHOH646
AGLY198
ASER199
AILE200
ACYS201
AASP234
AGLY235
AGLY236

site_idAC2
Number of Residues14
Detailsbinding site for residue FWV A 402
ChainResidue
APRO46
AHIS146
AGLY194
AGLY196
ATHR203
AMET284
AGLY285
AGLU318
AGLY346
ATYR347
AIMP401
AHOH542
AHOH593
AHOH622

Functional Information from PROSITE/UniProt
site_idPS00487
Number of Residues13
DetailsIMP_DH_GMP_RED IMP dehydrogenase / GMP reductase signature. VKVGVGpGSICtT
ChainResidueDetails
AVAL191-THR203

226262

PDB entries from 2024-10-16

PDB statisticsPDBj update infoContact PDBjnumon