6D31

Structure of human Usb1 with adenosine 5'-monophosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004518	molecular_function	nuclease activity
A	0034477	biological_process	U6 snRNA 3'-end processing

Functional Information from PDB Data

site_id	AC1
Number of Residues	19
Details	binding site for residue AMP A 301

Chain	Residue
A	HIS120
A	SER210
A	HOH408
A	HOH423
A	HOH434
A	HOH479
A	HOH496
A	HOH503
A	HOH522
A	HOH536
A	HOH567
A	SER122
A	THR162
A	ASN163
A	PHE170
A	TYR202
A	ASP204
A	SER206
A	HIS208

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site_id	AC2
Number of Residues	2
Details	binding site for residue CL A 302

Chain	Residue
A	PRO111
A	ARG112

---

site_id	AC3
Number of Residues	4
Details	binding site for residue GOL A 303

Chain	Residue
A	GLU93
A	ASP97
A	ASP100
A	ARG115

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	1
Details	Active site: {"description":"Proton acceptor","evidences":[{"source":"HAMAP-Rule","id":"MF_03040","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23190533","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30215753","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	1
Details	Active site: {"description":"Proton donor","evidences":[{"source":"HAMAP-Rule","id":"MF_03040","evidenceCode":"ECO:0000255"},{"source":"PubMed","id":"23190533","evidenceCode":"ECO:0000269"},{"source":"PubMed","id":"30215753","evidenceCode":"ECO:0000269"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	8
Details	Binding site: {"evidences":[{"source":"PubMed","id":"30215753","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"6D31","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	6
Details	Binding site: {"evidences":[{"source":"PubMed","id":"28887445","evidenceCode":"ECO:0000269"},{"source":"PDB","id":"5V1M","evidenceCode":"ECO:0007744"}]}

Chain

Residue

Details

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