6CZY

Crystal structure of Arabidopsis thaliana phosphoserine aminotransferase isoform 1 (AtPSAT1) in complex with Pyridoxamine-5'-phosphate (PMP)

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0004648	molecular_function	O-phospho-L-serine:2-oxoglutarate aminotransferase activity
A	0006564	biological_process	L-serine biosynthetic process
B	0004648	molecular_function	O-phospho-L-serine:2-oxoglutarate aminotransferase activity
B	0006564	biological_process	L-serine biosynthetic process
C	0004648	molecular_function	O-phospho-L-serine:2-oxoglutarate aminotransferase activity
C	0006564	biological_process	L-serine biosynthetic process
D	0004648	molecular_function	O-phospho-L-serine:2-oxoglutarate aminotransferase activity
D	0006564	biological_process	L-serine biosynthetic process

Functional Information from PDB Data

site_id	AC1
Number of Residues	18
Details	binding site for residue PMP A 501

Chain	Residue
A	GLY144
A	GLN264
A	LYS265
A	HOH623
A	HOH889
B	ASN306
B	THR307
B	SO4503
B	HOH716
B	HOH745
A	ALA145
A	THR146
A	TRP171
A	CYS217
A	ASN219
A	THR221
A	ASP241
A	SER243

---

site_id	AC2
Number of Residues	6
Details	binding site for residue SO4 A 502

Chain	Residue
A	GLY283
A	ASN284
A	LYS296
A	HOH639
A	HOH685
A	HOH797

---

site_id	AC3
Number of Residues	7
Details	binding site for residue SO4 A 503

Chain	Residue
A	HIS110
A	ARG111
A	HOH606
A	HOH641
A	HOH951
B	TRP171
B	PMP501

---

site_id	AC4
Number of Residues	7
Details	binding site for residue SO4 A 504

Chain	Residue
A	SER170
A	ASP173
A	LYS192
A	TYR196
A	HOH619
A	HOH734
A	HOH895

---

site_id	AC5
Number of Residues	6
Details	binding site for residue PEG A 505

Chain	Residue
A	GLY236
A	PHE237
A	ARG278
A	HOH716
A	HOH720
A	HOH724

---

site_id	AC6
Number of Residues	18
Details	binding site for residue PMP B 501

Chain	Residue
A	ASN306
A	THR307
A	SO4503
A	HOH641
A	HOH697
B	GLY144
B	ALA145
B	THR146
B	TRP171
B	CYS217
B	ASN219
B	THR221
B	ASP241
B	SER243
B	GLN264
B	LYS265
B	HOH608
B	HOH903

---

site_id	AC7
Number of Residues	5
Details	binding site for residue SO4 B 502

Chain	Residue
B	GLY283
B	ASN284
B	LYS296
B	HOH614
B	HOH670

---

site_id	AC8
Number of Residues	5
Details	binding site for residue SO4 B 503

Chain	Residue
A	TRP171
A	PMP501
B	HIS110
B	ARG111
B	HOH716

---

site_id	AC9
Number of Residues	6
Details	binding site for residue NA B 504

Chain	Residue
B	HOH610
B	HOH992
C	TRP189
C	SER190
C	HOH714
C	HOH977

---

site_id	AD1
Number of Residues	17
Details	binding site for residue PMP C 501

Chain	Residue
C	GLY144
C	ALA145
C	THR146
C	TRP171
C	CYS217
C	ASN219
C	THR221
C	ASP241
C	SER243
C	GLN264
C	LYS265
C	HOH634
C	HOH784
C	HOH835
D	ASN306
D	THR307
D	HOH661

---

site_id	AD2
Number of Residues	7
Details	binding site for residue MPD C 502

Chain	Residue
D	HOH820
D	HOH965
D	HOH1044
C	HIS110
C	ARG111
C	HOH739
D	HIS396

---

site_id	AD3
Number of Residues	7
Details	binding site for residue SO4 C 503

Chain	Residue
C	GLY283
C	ASN284
C	LYS296
C	HOH610
C	HOH620
C	HOH636
C	HOH657

---

site_id	AD4
Number of Residues	7
Details	binding site for residue PEG C 504

Chain	Residue
C	GLY236
C	PHE237
C	ARG278
C	HOH623
C	HOH702
C	HOH710
C	HOH725

---

site_id	AD5
Number of Residues	17
Details	binding site for residue PMP D 501

Chain	Residue
C	ASN306
C	THR307
D	GLY144
D	ALA145
D	THR146
D	TRP171
D	CYS217
D	ASN219
D	THR221
D	ASP241
D	SER243
D	GLN264
D	LYS265
D	HOH753
D	HOH754
D	HOH820
D	HOH867

---

site_id	AD6
Number of Residues	6
Details	binding site for residue SO4 D 502

Chain	Residue
D	GLY283
D	ASN284
D	LYS296
D	HOH671
D	HOH816
D	HOH930

---

Functional Information from PROSITE/UniProt

site_id	PS00595
Number of Residues	20
Details	AA_TRANSFER_CLASS_5 Aminotransferases class-V pyridoxal-phosphate attachment site. FGVIygGAQKnvgps.GvTiV

Chain	Residue	Details
A	PHE256-VAL275

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250

Chain	Residue	Details
A	ARG111
B	ARG111
C	ARG111
D	ARG111

---

site_id	SWS_FT_FI2
Number of Residues	20
Details	BINDING: BINDING => ECO:0000269|PubMed:30034403, ECO:0007744|PDB:6CZY, ECO:0007744|PDB:6CZZ

Chain	Residue	Details
A	ALA145
B	ASN306
C	ALA145
C	THR221
C	ASP241
C	GLN264
C	ASN306
D	ALA145
D	THR221
D	ASP241
D	GLN264
A	THR221
D	ASN306
A	ASP241
A	GLN264
A	ASN306
B	ALA145
B	THR221
B	ASP241
B	GLN264

---

site_id	SWS_FT_FI3
Number of Residues	4
Details	BINDING: BINDING => ECO:0000269|PubMed:30034403, ECO:0007744|PDB:6CZZ

Chain	Residue	Details
A	TRP171
B	TRP171
C	TRP171
D	TRP171

---

site_id	SWS_FT_FI4
Number of Residues	4
Details	MOD_RES: N6-(pyridoxal phosphate)lysine => ECO:0000269|PubMed:30034403, ECO:0007744|PDB:6CZY, ECO:0007744|PDB:6CZZ

Chain	Residue	Details
A	LYS265
B	LYS265
C	LYS265
D	LYS265

---