Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| A | 0007165 | biological_process | signal transduction |
| A | 0008081 | molecular_function | phosphoric diester hydrolase activity |
| B | 0004114 | molecular_function | 3',5'-cyclic-nucleotide phosphodiesterase activity |
| B | 0007165 | biological_process | signal transduction |
| B | 0008081 | molecular_function | phosphoric diester hydrolase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue ZN A 1001 |
| Chain | Residue |
| A | HIS660 |
| A | HIS696 |
| A | ASP697 |
| A | ASP808 |
| A | HOH1101 |
| A | HOH1202 |
| site_id | AC2 |
| Number of Residues | 6 |
| Details | binding site for residue MG A 1002 |
| Chain | Residue |
| A | HOH1120 |
| A | HOH1137 |
| A | HOH1220 |
| A | ASP697 |
| A | HOH1101 |
| A | HOH1103 |
| site_id | AC3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1003 |
| Chain | Residue |
| A | LEU770 |
| A | PHE830 |
| A | PHE862 |
| A | EDO1004 |
| A | FKV1008 |
| A | HOH1138 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 1004 |
| Chain | Residue |
| A | ASN704 |
| A | PHE830 |
| A | EDO1003 |
| A | EDO1005 |
| A | HOH1110 |
| A | HOH1196 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 1005 |
| Chain | Residue |
| A | ASP769 |
| A | LEU770 |
| A | EDO1004 |
| A | HOH1157 |
| site_id | AC6 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 1006 |
| Chain | Residue |
| A | ILE735 |
| A | ASN739 |
| A | TYR754 |
| A | HOH1124 |
| B | ARG751 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residue EDO A 1007 |
| Chain | Residue |
| A | ARG608 |
| A | TYR655 |
| A | HIS660 |
| A | SER663 |
| A | VAL664 |
| A | CYS807 |
| A | ASP808 |
| A | LEU809 |
| A | SER810 |
| A | ASP811 |
| A | FKV1008 |
| site_id | AC8 |
| Number of Residues | 18 |
| Details | binding site for residue FKV A 1008 |
| Chain | Residue |
| A | TYR655 |
| A | HIS656 |
| A | THR768 |
| A | LEU770 |
| A | THR805 |
| A | ASP808 |
| A | LEU809 |
| A | ASP811 |
| A | GLN812 |
| A | ILE822 |
| A | ILE826 |
| A | MET847 |
| A | GLN859 |
| A | PHE862 |
| A | EDO1003 |
| A | EDO1007 |
| A | HOH1116 |
| A | HOH1197 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue ZN B 1001 |
| Chain | Residue |
| B | HIS660 |
| B | HIS696 |
| B | ASP697 |
| B | ASP808 |
| B | HOH1101 |
| B | HOH1192 |
| site_id | AD1 |
| Number of Residues | 6 |
| Details | binding site for residue MG B 1002 |
| Chain | Residue |
| B | ASP697 |
| B | HOH1101 |
| B | HOH1104 |
| B | HOH1114 |
| B | HOH1157 |
| B | HOH1246 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO B 1003 |
| Chain | Residue |
| B | PHE862 |
| B | ILE866 |
| B | EDO1004 |
| B | FKV1006 |
| B | HOH1166 |
| site_id | AD3 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 1004 |
| Chain | Residue |
| B | ASN704 |
| B | PHE830 |
| B | MET848 |
| B | EDO1003 |
| B | EDO1005 |
| B | HOH1207 |
| site_id | AD4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO B 1005 |
| Chain | Residue |
| B | LEU770 |
| B | EDO1004 |
| B | HOH1103 |
| B | HOH1234 |
| site_id | AD5 |
| Number of Residues | 17 |
| Details | binding site for residue FKV B 1006 |
| Chain | Residue |
| B | ILE826 |
| B | GLN859 |
| B | PHE862 |
| B | EDO1003 |
| B | HOH1102 |
| B | HOH1119 |
| B | HOH1210 |
| B | TYR655 |
| B | HIS656 |
| B | THR768 |
| B | LEU770 |
| B | THR805 |
| B | ASP808 |
| B | LEU809 |
| B | ASP811 |
| B | GLN812 |
| B | ILE822 |
Functional Information from PROSITE/UniProt
| site_id | PS00126 |
| Number of Residues | 12 |
| Details | PDEASE_I_1 3'5'-cyclic nucleotide phosphodiesterase domain signature. HDLdHrGtnNsF |
| Chain | Residue | Details |
| A | HIS696-PHE707 | |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER912 | |
| B | SER912 | |
| Chain | Residue | Details |
| A | PHE687 | |
| B | GLN755 | |
| A | GLY702 | |
| A | SER721 | |
| A | ASN744 | |
| A | GLN755 | |
| B | PHE687 | |
| B | GLY702 | |
| B | SER721 | |
| B | ASN744 | |
| Chain | Residue | Details |
| A | LEU916 | |
| B | LEU916 | |
