6CXO

Complement component-9

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0001906	biological_process	cell killing
A	0002376	biological_process	immune system process
A	0005576	cellular_component	extracellular region
A	0005579	cellular_component	membrane attack complex
A	0005615	cellular_component	extracellular space
A	0005886	cellular_component	plasma membrane
A	0006955	biological_process	immune response
A	0006956	biological_process	complement activation
A	0006957	biological_process	complement activation, alternative pathway
A	0006958	biological_process	complement activation, classical pathway
A	0031640	biological_process	killing of cells of another organism
A	0044218	cellular_component	other organism cell membrane
A	0045087	biological_process	innate immune response
A	0050778	biological_process	positive regulation of immune response
A	0051260	biological_process	protein homooligomerization
A	0160257	biological_process	complement activation, GZMK pathway
A	1902495	cellular_component	transmembrane transporter complex
B	0001906	biological_process	cell killing
B	0002376	biological_process	immune system process
B	0005576	cellular_component	extracellular region
B	0005579	cellular_component	membrane attack complex
B	0005615	cellular_component	extracellular space
B	0005886	cellular_component	plasma membrane
B	0006955	biological_process	immune response
B	0006956	biological_process	complement activation
B	0006957	biological_process	complement activation, alternative pathway
B	0006958	biological_process	complement activation, classical pathway
B	0031640	biological_process	killing of cells of another organism
B	0044218	cellular_component	other organism cell membrane
B	0045087	biological_process	innate immune response
B	0050778	biological_process	positive regulation of immune response
B	0051260	biological_process	protein homooligomerization
B	0160257	biological_process	complement activation, GZMK pathway
B	1902495	cellular_component	transmembrane transporter complex

Functional Information from PROSITE/UniProt

site_id	PS00022
Number of Residues	12
Details	EGF_1 EGF-like domain signature 1. CsCpmMfrGMaC

Chain	Residue	Details
A	CYS511-CYS522

---

site_id	PS00279
Number of Residues	12
Details	MACPF_1 Membrane attack complex/perforin (MACPF) domain signature. YfgfletYGTHY

Chain	Residue	Details
A	TYR313-TYR324

---

site_id	PS01209
Number of Residues	23
Details	LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CIkrrll.CNgdnDCgdy.SDEnd...C

Chain	Residue	Details
A	CYS90-CYS112

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	21
Details	Transmembrane: {"description":"Beta stranded","evidences":[{"source":"UniProtKB","id":"P02748","evidenceCode":"ECO:0000250"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI2
Number of Residues	53
Details	Domain: {"description":"TSP type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00210","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI3
Number of Residues	37
Details	Domain: {"description":"LDL-receptor class A","evidences":[{"source":"PROSITE-ProRule","id":"PRU00124","evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---

site_id	SWS_FT_FI4
Number of Residues	60
Details	Domain: {"description":"EGF-like"}

Chain

Residue

Details

---

site_id	SWS_FT_FI5
Number of Residues	4
Details	Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]}

Chain

Residue

Details

---