6CXO
Complement component-9
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0001906 | biological_process | cell killing |
| A | 0005576 | cellular_component | extracellular region |
| A | 0005579 | cellular_component | membrane attack complex |
| A | 0005886 | cellular_component | plasma membrane |
| A | 0006955 | biological_process | immune response |
| A | 0006956 | biological_process | complement activation |
| A | 0022829 | molecular_function | wide pore channel activity |
| A | 0031640 | biological_process | killing of cells of another organism |
| A | 0044218 | cellular_component | other organism cell membrane |
| A | 0050778 | biological_process | positive regulation of immune response |
| A | 0051260 | biological_process | protein homooligomerization |
| A | 0055085 | biological_process | transmembrane transport |
| A | 0160257 | biological_process | complement activation, GZMK pathway |
| A | 1902495 | cellular_component | transmembrane transporter complex |
| B | 0001906 | biological_process | cell killing |
| B | 0005576 | cellular_component | extracellular region |
| B | 0005579 | cellular_component | membrane attack complex |
| B | 0005886 | cellular_component | plasma membrane |
| B | 0006955 | biological_process | immune response |
| B | 0006956 | biological_process | complement activation |
| B | 0022829 | molecular_function | wide pore channel activity |
| B | 0031640 | biological_process | killing of cells of another organism |
| B | 0044218 | cellular_component | other organism cell membrane |
| B | 0050778 | biological_process | positive regulation of immune response |
| B | 0051260 | biological_process | protein homooligomerization |
| B | 0055085 | biological_process | transmembrane transport |
| B | 0160257 | biological_process | complement activation, GZMK pathway |
| B | 1902495 | cellular_component | transmembrane transporter complex |
Functional Information from PROSITE/UniProt
| site_id | PS00022 |
| Number of Residues | 12 |
| Details | EGF_1 EGF-like domain signature 1. CsCpmMfrGMaC |
| Chain | Residue | Details |
| A | CYS511-CYS522 |
| site_id | PS00279 |
| Number of Residues | 12 |
| Details | MACPF_1 Membrane attack complex/perforin (MACPF) domain signature. YfgfletYGTHY |
| Chain | Residue | Details |
| A | TYR313-TYR324 |
| site_id | PS01209 |
| Number of Residues | 23 |
| Details | LDLRA_1 LDL-receptor class A (LDLRA) domain signature. CIkrrll.CNgdnDCgdy.SDEnd...C |
| Chain | Residue | Details |
| A | CYS90-CYS112 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 21 |
| Details | Transmembrane: {"description":"Beta stranded","evidences":[{"source":"UniProtKB","id":"P02748","evidenceCode":"ECO:0000250"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI2 |
| Number of Residues | 53 |
| Details | Domain: {"description":"TSP type-1","evidences":[{"source":"PROSITE-ProRule","id":"PRU00210","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI3 |
| Number of Residues | 37 |
| Details | Domain: {"description":"LDL-receptor class A","evidences":[{"source":"PROSITE-ProRule","id":"PRU00124","evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI4 |
| Number of Residues | 60 |
| Details | Domain: {"description":"EGF-like"} |
| Chain | Residue | Details |
| site_id | SWS_FT_FI5 |
| Number of Residues | 4 |
| Details | Glycosylation: {"description":"N-linked (GlcNAc...) asparagine","evidences":[{"evidenceCode":"ECO:0000255"}]} |
| Chain | Residue | Details |
