6CW2

Crystal structure of a yeast SAGA transcriptional coactivator Ada2/Gcn5 HAT subcomplex, crystal form 1

Functional Information from GO Data

Chain	GOid	namespace	contents
C	0008270	molecular_function	zinc ion binding
D	0004402	molecular_function	histone acetyltransferase activity
D	0016747	molecular_function	acyltransferase activity, transferring groups other than amino-acyl groups

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN C 201

Chain	Residue
C	CYS22
C	CYS25
C	HIS44
C	HIS48

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN C 202

Chain	Residue
C	CYS7
C	CYS10
C	CYS31
C	CYS34

---

Functional Information from PROSITE/UniProt

site_id	PS00290
Number of Residues	7
Details	IG_MHC Immunoglobulins and major histocompatibility complex proteins signature. YACEVTH

Chain	Residue	Details
B	TYR193-HIS199
A	TYR213-HIS219

---

site_id	PS01357
Number of Residues	28
Details	ZF_ZZ_1 Zinc finger ZZ-type signature. CdvCsadctnrvRVsCai...CpEYdLCvpC

Chain	Residue	Details
C	CYS7-CYS34

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	56
Details	ZN_FING: ZZ-type => ECO:0000255|PROSITE-ProRule:PRU00228

Chain	Residue	Details
C	SER2-TYR58

---

site_id	SWS_FT_FI2
Number of Residues	8
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00228

Chain	Residue	Details
C	CYS7
C	CYS10
C	CYS22
C	CYS25
C	CYS31
C	CYS34
C	HIS44
C	HIS48

---

site_id	SWS_FT_FI3
Number of Residues	1
Details	SITE: Important for catalytic activity

Chain	Residue	Details
D	GLU173

---