6CVC
Mycobacterium marinum cytochrome P450 CYP124A1 in the substrate-free form
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0004497 | molecular_function | monooxygenase activity |
| A | 0005506 | molecular_function | iron ion binding |
| A | 0006707 | biological_process | cholesterol catabolic process |
| A | 0008395 | molecular_function | steroid hydroxylase activity |
| A | 0016491 | molecular_function | oxidoreductase activity |
| A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
| A | 0020037 | molecular_function | heme binding |
| A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
| A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 29 |
| Details | binding site for residue HEM A 501 |
| Chain | Residue |
| A | MET110 |
| A | THR272 |
| A | ALA275 |
| A | PRO314 |
| A | VAL315 |
| A | ARG320 |
| A | GLY370 |
| A | PHE371 |
| A | GLY372 |
| A | ALA376 |
| A | HIS377 |
| A | ILE111 |
| A | CYS379 |
| A | GLY381 |
| A | LEU384 |
| A | ALA385 |
| A | GLU388 |
| A | HOH667 |
| A | HOH670 |
| A | HOH674 |
| A | HOH698 |
| A | HOH739 |
| A | HIS118 |
| A | ARG122 |
| A | LEU263 |
| A | LEU264 |
| A | ALA267 |
| A | GLY268 |
| A | THR271 |
| site_id | AC2 |
| Number of Residues | 3 |
| Details | binding site for residue SO4 A 502 |
| Chain | Residue |
| A | ARG142 |
| A | ARG390 |
| A | HOH713 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 503 |
| Chain | Residue |
| A | GLY66 |
| A | LYS67 |
| A | HIS97 |
| A | LYS338 |
| A | HOH601 |
| site_id | AC4 |
| Number of Residues | 5 |
| Details | binding site for residue SO4 A 504 |
| Chain | Residue |
| A | ARG136 |
| A | HIS235 |
| A | GLY236 |
| A | HOH752 |
| A | HOH774 |
