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6CVC

Mycobacterium marinum cytochrome P450 CYP124A1 in the substrate-free form

Functional Information from GO Data
ChainGOidnamespacecontents
A0004497molecular_functionmonooxygenase activity
A0005506molecular_functioniron ion binding
A0006707biological_processcholesterol catabolic process
A0008395molecular_functionsteroid hydroxylase activity
A0016705molecular_functionoxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen
A0020037molecular_functionheme binding
A0036199molecular_functioncholest-4-en-3-one 26-monooxygenase activity
A0046872molecular_functionmetal ion binding
Functional Information from PDB Data
site_idAC1
Number of Residues29
Detailsbinding site for residue HEM A 501
ChainResidue
AMET110
ATHR272
AALA275
APRO314
AVAL315
AARG320
AGLY370
APHE371
AGLY372
AALA376
AHIS377
AILE111
ACYS379
AGLY381
ALEU384
AALA385
AGLU388
AHOH667
AHOH670
AHOH674
AHOH698
AHOH739
AHIS118
AARG122
ALEU263
ALEU264
AALA267
AGLY268
ATHR271

site_idAC2
Number of Residues3
Detailsbinding site for residue SO4 A 502
ChainResidue
AARG142
AARG390
AHOH713

site_idAC3
Number of Residues5
Detailsbinding site for residue SO4 A 503
ChainResidue
AGLY66
ALYS67
AHIS97
ALYS338
AHOH601

site_idAC4
Number of Residues5
Detailsbinding site for residue SO4 A 504
ChainResidue
AARG136
AHIS235
AGLY236
AHOH752
AHOH774

227344

PDB entries from 2024-11-13

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