6CVC
Mycobacterium marinum cytochrome P450 CYP124A1 in the substrate-free form
Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004497 | molecular_function | monooxygenase activity |
A | 0005506 | molecular_function | iron ion binding |
A | 0006707 | biological_process | cholesterol catabolic process |
A | 0008395 | molecular_function | steroid hydroxylase activity |
A | 0016705 | molecular_function | oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen |
A | 0020037 | molecular_function | heme binding |
A | 0036199 | molecular_function | cholest-4-en-3-one 26-monooxygenase activity |
A | 0046872 | molecular_function | metal ion binding |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 29 |
Details | binding site for residue HEM A 501 |
Chain | Residue |
A | MET110 |
A | THR272 |
A | ALA275 |
A | PRO314 |
A | VAL315 |
A | ARG320 |
A | GLY370 |
A | PHE371 |
A | GLY372 |
A | ALA376 |
A | HIS377 |
A | ILE111 |
A | CYS379 |
A | GLY381 |
A | LEU384 |
A | ALA385 |
A | GLU388 |
A | HOH667 |
A | HOH670 |
A | HOH674 |
A | HOH698 |
A | HOH739 |
A | HIS118 |
A | ARG122 |
A | LEU263 |
A | LEU264 |
A | ALA267 |
A | GLY268 |
A | THR271 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue SO4 A 502 |
Chain | Residue |
A | ARG142 |
A | ARG390 |
A | HOH713 |
site_id | AC3 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 503 |
Chain | Residue |
A | GLY66 |
A | LYS67 |
A | HIS97 |
A | LYS338 |
A | HOH601 |
site_id | AC4 |
Number of Residues | 5 |
Details | binding site for residue SO4 A 504 |
Chain | Residue |
A | ARG136 |
A | HIS235 |
A | GLY236 |
A | HOH752 |
A | HOH774 |