6CV6
Crystal structure of 3-dehydroquinate dehydratase, type II, from Burkholderia phymatum STM815
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| A | 0008652 | biological_process | amino acid biosynthetic process |
| A | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| A | 0009423 | biological_process | chorismate biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0019631 | biological_process | quinate catabolic process |
| B | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| B | 0008652 | biological_process | amino acid biosynthetic process |
| B | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| B | 0009423 | biological_process | chorismate biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0019631 | biological_process | quinate catabolic process |
| C | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| C | 0008652 | biological_process | amino acid biosynthetic process |
| C | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| C | 0009423 | biological_process | chorismate biosynthetic process |
| C | 0016829 | molecular_function | lyase activity |
| C | 0019631 | biological_process | quinate catabolic process |
| D | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| D | 0008652 | biological_process | amino acid biosynthetic process |
| D | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| D | 0009423 | biological_process | chorismate biosynthetic process |
| D | 0016829 | molecular_function | lyase activity |
| D | 0019631 | biological_process | quinate catabolic process |
| E | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| E | 0008652 | biological_process | amino acid biosynthetic process |
| E | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| E | 0009423 | biological_process | chorismate biosynthetic process |
| E | 0016829 | molecular_function | lyase activity |
| E | 0019631 | biological_process | quinate catabolic process |
| F | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| F | 0008652 | biological_process | amino acid biosynthetic process |
| F | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| F | 0009423 | biological_process | chorismate biosynthetic process |
| F | 0016829 | molecular_function | lyase activity |
| F | 0019631 | biological_process | quinate catabolic process |
| G | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| G | 0008652 | biological_process | amino acid biosynthetic process |
| G | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| G | 0009423 | biological_process | chorismate biosynthetic process |
| G | 0016829 | molecular_function | lyase activity |
| G | 0019631 | biological_process | quinate catabolic process |
| H | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| H | 0008652 | biological_process | amino acid biosynthetic process |
| H | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| H | 0009423 | biological_process | chorismate biosynthetic process |
| H | 0016829 | molecular_function | lyase activity |
| H | 0019631 | biological_process | quinate catabolic process |
| I | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| I | 0008652 | biological_process | amino acid biosynthetic process |
| I | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| I | 0009423 | biological_process | chorismate biosynthetic process |
| I | 0016829 | molecular_function | lyase activity |
| I | 0019631 | biological_process | quinate catabolic process |
| J | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| J | 0008652 | biological_process | amino acid biosynthetic process |
| J | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| J | 0009423 | biological_process | chorismate biosynthetic process |
| J | 0016829 | molecular_function | lyase activity |
| J | 0019631 | biological_process | quinate catabolic process |
| K | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| K | 0008652 | biological_process | amino acid biosynthetic process |
| K | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| K | 0009423 | biological_process | chorismate biosynthetic process |
| K | 0016829 | molecular_function | lyase activity |
| K | 0019631 | biological_process | quinate catabolic process |
| L | 0003855 | molecular_function | 3-dehydroquinate dehydratase activity |
| L | 0008652 | biological_process | amino acid biosynthetic process |
| L | 0009073 | biological_process | aromatic amino acid family biosynthetic process |
| L | 0009423 | biological_process | chorismate biosynthetic process |
| L | 0016829 | molecular_function | lyase activity |
| L | 0019631 | biological_process | quinate catabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue TLA A 200 |
| Chain | Residue |
| A | TYR84 |
| A | ARG87 |
| A | HIS114 |
| A | SER115 |
| A | VAL116 |
| A | GLU119 |
| A | HOH342 |
| B | PHE111 |
| site_id | AC2 |
| Number of Residues | 11 |
| Details | binding site for residue TLA A 201 |
| Chain | Residue |
| A | ASN75 |
| A | GLY77 |
| A | HIS101 |
| A | MET102 |
| A | SER103 |
| A | ARG108 |
| A | ARG112 |
| A | HOH301 |
| A | HOH353 |
| E | HOH340 |
| A | HIS12 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue TLA B 201 |
| Chain | Residue |
| B | TYR84 |
| B | ARG87 |
| B | HIS114 |
| B | VAL116 |
| B | GLU119 |
| E | GLU109 |
| E | PHE111 |
| site_id | AC4 |
| Number of Residues | 10 |
| Details | binding site for residue TLA B 202 |
| Chain | Residue |
| A | HOH316 |
| B | HIS12 |
| B | ASN75 |
| B | GLY77 |
| B | HIS101 |
| B | MET102 |
| B | SER103 |
| B | HOH301 |
| B | HOH302 |
| B | HOH354 |
| site_id | AC5 |
| Number of Residues | 8 |
| Details | binding site for residue TAR B 203 |
| Chain | Residue |
| B | HIS106 |
| B | HIS106 |
| B | HIS113 |
| B | HIS113 |
| B | HIS114 |
| B | HIS114 |
| B | HOH308 |
| B | HOH344 |
| site_id | AC6 |
| Number of Residues | 4 |
| Details | binding site for residue CL B 204 |
| Chain | Residue |
| B | ARG138 |
| B | ARG138 |
| G | ARG138 |
| G | ARG138 |
| site_id | AC7 |
| Number of Residues | 9 |
| Details | binding site for residue TLA C 200 |
| Chain | Residue |
| C | TYR84 |
| C | ARG87 |
| C | HIS114 |
| C | SER115 |
| C | VAL116 |
| C | GLU119 |
| C | HOH320 |
| C | HOH344 |
| D | PHE111 |
| site_id | AC8 |
| Number of Residues | 10 |
| Details | binding site for residue TLA C 201 |
| Chain | Residue |
| C | HIS12 |
| C | ARG18 |
| C | TYR23 |
| C | ASN75 |
| C | GLY77 |
| C | HIS101 |
| C | MET102 |
| C | SER103 |
| C | ARG112 |
| F | ASP88 |
| site_id | AC9 |
| Number of Residues | 9 |
| Details | binding site for residue TLA D 200 |
| Chain | Residue |
| D | TYR84 |
| D | ARG87 |
| D | HIS114 |
| D | SER115 |
| D | VAL116 |
| D | GLU119 |
| D | HOH354 |
| F | GLU109 |
| F | PHE111 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residue TLA D 201 |
| Chain | Residue |
| C | ASP88 |
| D | HIS12 |
| D | ARG18 |
| D | TYR23 |
| D | ASN75 |
| D | GLY77 |
| D | HIS101 |
| D | MET102 |
| D | SER103 |
| D | ARG112 |
| D | HOH331 |
| site_id | AD2 |
| Number of Residues | 5 |
| Details | binding site for residue TAR D 202 |
| Chain | Residue |
| D | HIS106 |
| D | HIS113 |
| D | HIS113 |
| D | HIS114 |
| D | HIS114 |
| site_id | AD3 |
| Number of Residues | 8 |
| Details | binding site for residue TLA E 200 |
| Chain | Residue |
| E | HOH310 |
| A | PHE111 |
| E | TYR84 |
| E | ARG87 |
| E | HIS114 |
| E | SER115 |
| E | VAL116 |
| E | GLU119 |
| site_id | AD4 |
| Number of Residues | 10 |
| Details | binding site for residue TLA E 201 |
| Chain | Residue |
| E | HIS12 |
| E | ASN75 |
| E | GLY77 |
| E | HIS101 |
| E | MET102 |
| E | SER103 |
| E | ARG108 |
| E | HOH301 |
| E | HOH302 |
| E | HOH337 |
| site_id | AD5 |
| Number of Residues | 9 |
| Details | binding site for residue TLA F 200 |
| Chain | Residue |
| C | PHE111 |
| F | TYR84 |
| F | ARG87 |
| F | HIS114 |
| F | SER115 |
| F | VAL116 |
| F | GLU119 |
| F | HOH328 |
| F | HOH337 |
| site_id | AD6 |
| Number of Residues | 8 |
| Details | binding site for residue TLA F 201 |
| Chain | Residue |
| D | HOH317 |
| F | HIS12 |
| F | ASN75 |
| F | GLY77 |
| F | HIS101 |
| F | MET102 |
| F | SER103 |
| F | HOH301 |
| site_id | AD7 |
| Number of Residues | 9 |
| Details | binding site for residue TLA G 200 |
| Chain | Residue |
| G | TYR84 |
| G | ARG87 |
| G | HIS114 |
| G | SER115 |
| G | VAL116 |
| G | GLU119 |
| I | GLU109 |
| I | PHE111 |
| I | HOH316 |
| site_id | AD8 |
| Number of Residues | 9 |
| Details | binding site for residue TLA G 201 |
| Chain | Residue |
| G | HIS12 |
| G | ASN75 |
| G | GLY77 |
| G | HIS101 |
| G | MET102 |
| G | SER103 |
| G | ARG108 |
| G | HOH301 |
| H | HOH329 |
| site_id | AD9 |
| Number of Residues | 8 |
| Details | binding site for residue TAR G 202 |
| Chain | Residue |
| G | HIS106 |
| G | HIS113 |
| G | HIS113 |
| G | HIS114 |
| G | HIS114 |
| G | HOH303 |
| G | HOH318 |
| G | HOH318 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue TLA H 200 |
| Chain | Residue |
| G | PHE111 |
| H | TYR84 |
| H | ARG87 |
| H | HIS114 |
| H | VAL116 |
| H | GLU119 |
| H | HOH301 |
| site_id | AE2 |
| Number of Residues | 8 |
| Details | binding site for residue TLA H 201 |
| Chain | Residue |
| H | HIS12 |
| H | ASN75 |
| H | GLY77 |
| H | HIS101 |
| H | MET102 |
| H | SER103 |
| H | ARG108 |
| H | HOH307 |
| site_id | AE3 |
| Number of Residues | 8 |
| Details | binding site for residue TLA I 200 |
| Chain | Residue |
| H | PHE111 |
| H | HOH327 |
| I | TYR84 |
| I | ARG87 |
| I | HIS114 |
| I | SER115 |
| I | VAL116 |
| I | GLU119 |
| site_id | AE4 |
| Number of Residues | 10 |
| Details | binding site for residue TLA I 201 |
| Chain | Residue |
| I | HIS12 |
| I | PHE15 |
| I | ASN75 |
| I | GLY77 |
| I | HIS101 |
| I | MET102 |
| I | SER103 |
| I | ARG108 |
| I | HOH301 |
| I | HOH302 |
| site_id | AE5 |
| Number of Residues | 6 |
| Details | binding site for residue TLA J 200 |
| Chain | Residue |
| J | TYR84 |
| J | ARG87 |
| J | HIS114 |
| J | VAL116 |
| J | GLU119 |
| K | PHE111 |
| site_id | AE6 |
| Number of Residues | 9 |
| Details | binding site for residue TLA J 201 |
| Chain | Residue |
| J | HIS12 |
| J | ASN75 |
| J | GLY77 |
| J | HIS101 |
| J | MET102 |
| J | SER103 |
| J | VAL105 |
| J | HOH302 |
| J | HOH303 |
| site_id | AE7 |
| Number of Residues | 7 |
| Details | binding site for residue TLA K 200 |
| Chain | Residue |
| K | TYR84 |
| K | ARG87 |
| K | HIS114 |
| K | SER115 |
| K | VAL116 |
| K | GLU119 |
| L | PHE111 |
| site_id | AE8 |
| Number of Residues | 6 |
| Details | binding site for residue TLA K 201 |
| Chain | Residue |
| K | HIS12 |
| K | ASN75 |
| K | HIS101 |
| K | MET102 |
| K | SER103 |
| K | ARG108 |
| site_id | AE9 |
| Number of Residues | 5 |
| Details | binding site for residue TAR K 202 |
| Chain | Residue |
| K | HIS106 |
| K | HIS113 |
| K | HIS113 |
| K | HIS114 |
| K | HIS114 |
| site_id | AF1 |
| Number of Residues | 7 |
| Details | binding site for residue TLA L 200 |
| Chain | Residue |
| J | PHE111 |
| J | HOH306 |
| L | TYR84 |
| L | ARG87 |
| L | HIS114 |
| L | SER115 |
| L | VAL116 |
| site_id | AF2 |
| Number of Residues | 8 |
| Details | binding site for residue TLA L 201 |
| Chain | Residue |
| L | HIS12 |
| L | ASN75 |
| L | GLY77 |
| L | HIS101 |
| L | MET102 |
| L | SER103 |
| L | VAL105 |
| L | ARG108 |
