6COI
AtHNL enantioselectivity mutant At-A9-H7 Apo, Y13C,Y121L,P126F,L128W,C131T,A209I with CYANIDE, benzaldehyde, MANDELIC ACID NITRILE
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0005515 | molecular_function | protein binding |
| A | 0009611 | biological_process | response to wounding |
| A | 0016139 | biological_process | glycoside catabolic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0046593 | molecular_function | mandelonitrile lyase activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0009611 | biological_process | response to wounding |
| B | 0016139 | biological_process | glycoside catabolic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0046593 | molecular_function | mandelonitrile lyase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 7 |
| Details | binding site for residue GOL A 301 |
| Chain | Residue |
| A | GLU53 |
| A | ASN141 |
| A | THR143 |
| A | MET144 |
| A | ASP183 |
| A | LYS186 |
| A | HOH414 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue CYN A 302 |
| Chain | Residue |
| A | SER81 |
| A | PHE82 |
| A | HBX303 |
| A | ASN12 |
| A | ALA13 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue HBX A 303 |
| Chain | Residue |
| A | ASN12 |
| A | ALA13 |
| A | SER81 |
| A | TRP129 |
| A | LEU147 |
| A | PHE179 |
| A | HIS236 |
| A | CYN302 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue HBX A 304 |
| Chain | Residue |
| A | PHE107 |
| A | MET123 |
| A | PHE126 |
| A | TRP129 |
| A | PHE179 |
| A | ILE210 |
| site_id | AC5 |
| Number of Residues | 6 |
| Details | binding site for residue HBX B 301 |
| Chain | Residue |
| B | PHE107 |
| B | LEU119 |
| B | MET123 |
| B | TRP129 |
| B | PHE179 |
| B | MXN302 |
| site_id | AC6 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AC7 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AC8 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AC9 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AD1 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AD2 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AD3 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| B | ASN12 |
| site_id | AD4 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AD5 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AD6 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AD7 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AD8 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
| site_id | AD9 |
| Number of Residues | 11 |
| Details | binding site for residues MXN B 302 and MNN B 303 |
| Chain | Residue |
| B | ASN12 |
| B | ALA13 |
| B | SER81 |
| B | PHE82 |
| B | TRP129 |
| B | MET149 |
| B | PHE153 |
| B | LEU158 |
| B | PHE179 |
| B | HIS236 |
| B | HBX301 |
Functional Information from SwissProt/UniProt
| Chain | Residue | Details |
| A | SER81 | |
| A | HIS236 | |
| B | SER81 | |
| B | HIS236 | |
| Chain | Residue | Details |
| A | ASP208 | |
| B | ASP208 | |
