6COH

AtHNL enantioselectivity mutant At-A9-H7 Apo, Y13C,Y121L,P126F,L128W,C131T,A209I with benzaldehyde, MANDELIC ACID NITRILE

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0002213	biological_process	defense response to insect
A	0003824	molecular_function	catalytic activity
A	0005515	molecular_function	protein binding
A	0005634	cellular_component	nucleus
A	0005737	cellular_component	cytoplasm
A	0005886	cellular_component	plasma membrane
A	0009611	biological_process	response to wounding
A	0009694	biological_process	jasmonic acid metabolic process
A	0009696	biological_process	salicylic acid metabolic process
A	0016139	biological_process	glycoside catabolic process
A	0016829	molecular_function	lyase activity
A	0046593	molecular_function	mandelonitrile lyase activity
A	0080030	molecular_function	methyl indole-3-acetate esterase activity
A	0080031	molecular_function	methyl salicylate esterase activity
A	0080032	molecular_function	methyl jasmonate esterase activity
B	0002213	biological_process	defense response to insect
B	0003824	molecular_function	catalytic activity
B	0005515	molecular_function	protein binding
B	0005634	cellular_component	nucleus
B	0005737	cellular_component	cytoplasm
B	0005886	cellular_component	plasma membrane
B	0009611	biological_process	response to wounding
B	0009694	biological_process	jasmonic acid metabolic process
B	0009696	biological_process	salicylic acid metabolic process
B	0016139	biological_process	glycoside catabolic process
B	0016829	molecular_function	lyase activity
B	0046593	molecular_function	mandelonitrile lyase activity
B	0080030	molecular_function	methyl indole-3-acetate esterase activity
B	0080031	molecular_function	methyl salicylate esterase activity
B	0080032	molecular_function	methyl jasmonate esterase activity

Functional Information from PDB Data

site_id	AC1
Number of Residues	7
Details	binding site for residue MXN A 301

Chain	Residue
A	ASN12
A	ALA13
A	SER81
A	PHE82
A	MET149
A	PHE179
A	HIS236

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site_id	AC2
Number of Residues	7
Details	binding site for residue GOL A 302

Chain	Residue
A	ASN141
A	MET144
A	ASP183
A	LYS186
A	HOH406
A	GLU53
A	THR139

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site_id	AC3
Number of Residues	4
Details	binding site for residue HBX B 301

Chain	Residue
B	PHE107
B	MET123
B	PHE179
B	MXN302

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site_id	AC4
Number of Residues	7
Details	binding site for residue MXN B 302

Chain	Residue
B	ASN12
B	ALA13
B	SER81
B	PHE82
B	MET149
B	HIS236
B	HBX301

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Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	ACT_SITE: Proton donor/acceptor => ECO:0000250|UniProtKB:P52704

Chain	Residue	Details
A	SER81
A	HIS236
B	SER81
B	HIS236

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site_id	SWS_FT_FI2
Number of Residues	2
Details	SITE: Increases basicity of active site His => ECO:0000250|UniProtKB:P52704

Chain	Residue	Details
A	ASP208
B	ASP208

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