6CNG

The X-ray crystal structure of the Streptococcus pneumoniae Fatty Acid Kinase (Fak) B3 protein loaded with linoleic acid to 1.47 Angstrom resolution

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008289	molecular_function	lipid binding
D	0008289	molecular_function	lipid binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	11
Details	binding site for residue EIC A 301

Chain	Residue
A	LEU30
A	HOH415
A	HOH420
A	SER63
A	ALA64
A	CYS65
A	SER91
A	PHE160
A	GLY197
A	TYR268
A	LEU275

---

site_id	AC2
Number of Residues	4
Details	binding site for residue NA A 302

Chain	Residue
A	GLU124
A	GLN153
A	THR156
A	HOH552

---

site_id	AC3
Number of Residues	3
Details	binding site for residue GOL A 303

Chain	Residue
A	GLU130
A	ASP255
A	HOH463

---

site_id	AC4
Number of Residues	6
Details	binding site for residue GOL A 304

Chain	Residue
A	LYS101
A	ILE113
A	PHE142
A	GLU143
A	HOH433
A	HOH445

---

site_id	AC5
Number of Residues	4
Details	binding site for residue GOL A 305

Chain	Residue
A	LYS131
A	GLU279
A	GOL306
A	HOH525

---

site_id	AC6
Number of Residues	5
Details	binding site for residue GOL A 306

Chain	Residue
A	ALA225
A	GLY227
A	GOL305
A	HOH449
D	ASN186

---

site_id	AC7
Number of Residues	4
Details	binding site for residue ACT A 307

Chain	Residue
A	LYS164
A	ASP166
A	HOH682
D	PRO252

---

site_id	AC8
Number of Residues	7
Details	binding site for residue ACT A 308

Chain	Residue
A	ARG234
A	ASN235
A	GLU237
A	HOH402
D	LYS221
D	HOH430
D	HOH754

---

site_id	AC9
Number of Residues	15
Details	binding site for residue EIC D 301

Chain	Residue
D	LEU30
D	SER63
D	ALA64
D	CYS65
D	LEU90
D	SER91
D	LEU158
D	ARG173
D	ALA193
D	GLY197
D	THR198
D	TYR268
D	LEU275
D	HOH414
D	HOH531

---

site_id	AD1
Number of Residues	7
Details	binding site for residue NA D 302

Chain	Residue
D	GLU124
D	GLN153
D	THR156
D	LYS157
D	GOL304
D	HOH415
D	HOH425

---

site_id	AD2
Number of Residues	6
Details	binding site for residue GOL D 303

Chain	Residue
A	LYS221
A	HOH405
D	GLU237
D	LYS238
D	GLN241
D	HOH405

---

site_id	AD3
Number of Residues	8
Details	binding site for residue GOL D 304

Chain	Residue
D	LYS157
D	LYS192
D	ALA193
D	SER194
D	GLU195
D	NA302
D	HOH415
D	HOH607

---

site_id	AD4
Number of Residues	4
Details	binding site for residue GOL D 305

Chain	Residue
A	LYS238
D	LYS192
D	GLU200
D	HOH480

---

site_id	AD5
Number of Residues	3
Details	binding site for residue GOL D 306

Chain	Residue
D	ASP166
D	VAL169
D	HOH406

---

site_id	AD6
Number of Residues	4
Details	binding site for residue GOL D 307

Chain	Residue
A	ASP69
D	VAL169
D	LYS170
D	LYS176

---

site_id	AD7
Number of Residues	3
Details	binding site for residue GOL D 308

Chain	Residue
D	LYS101
D	HIS114
D	VAL115

---

site_id	AD8
Number of Residues	2
Details	binding site for residue GOL D 309

Chain	Residue
D	ACT312
D	HOH532

---

site_id	AD9
Number of Residues	5
Details	binding site for residue GOL D 310

Chain	Residue
D	HOH486
D	HOH557
D	PRO109
D	ASP110
D	THR111

---

site_id	AE1
Number of Residues	3
Details	binding site for residue GOL D 311

Chain	Residue
A	TYR55
D	GLU249
D	PRO252

---

site_id	AE2
Number of Residues	7
Details	binding site for residue ACT D 312

Chain	Residue
D	MET1
D	TRP3
D	ILE21
D	ASN22
D	GOL309
D	HOH459
D	HOH520

---

site_id	AE3
Number of Residues	6
Details	binding site for residue ACT D 313

Chain	Residue
A	HOH622
D	LEU184
D	LEU185
D	ASN186
D	HOH419
D	HOH482

---

site_id	AE4
Number of Residues	3
Details	binding site for residue ACT D 314

Chain	Residue
D	VAL38
D	PHE39
D	HOH597

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	4
Details	BINDING: BINDING => ECO:0000250|UniProtKB:Q9X1H9

Chain	Residue	Details
A	SER63
A	SER91
D	SER63
D	SER91

---