Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 6 |
| Details | binding site for residue FE A 701 |
| Chain | Residue |
| A | HIS562 |
| A | HIS564 |
| B | HIS562 |
| B | HIS564 |
| C | HIS562 |
| C | HIS564 |
| site_id | AC2 |
| Number of Residues | 7 |
| Details | binding site for residue MG A 702 |
| Chain | Residue |
| B | HOH884 |
| B | HOH1101 |
| C | HOH830 |
| C | HOH1099 |
| A | ASP613 |
| A | HOH865 |
| A | HOH1085 |
| site_id | AC3 |
| Number of Residues | 7 |
| Details | binding site for residue CA A 703 |
| Chain | Residue |
| A | ASP628 |
| A | GLY677 |
| A | HOH819 |
| A | HOH886 |
| A | HOH989 |
| C | PRO656 |
| C | HOH1101 |
| site_id | AC4 |
| Number of Residues | 6 |
| Details | binding site for residue EDO A 704 |
| Chain | Residue |
| A | TYR398 |
| A | HOH853 |
| C | ASN365 |
| C | LEU378 |
| C | TYR390 |
| C | HOH1040 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 705 |
| Chain | Residue |
| A | SER471 |
| A | PHE472 |
| A | THR473 |
| A | ALA487 |
| A | TYR507 |
| A | HOH896 |
| B | HIS518 |
| site_id | AC6 |
| Number of Residues | 6 |
| Details | binding site for residue CA A 706 |
| Chain | Residue |
| A | PRO656 |
| A | EDO707 |
| B | ASP628 |
| B | ASP659 |
| B | GLY677 |
| B | HOH895 |
| site_id | AC7 |
| Number of Residues | 7 |
| Details | binding site for residue EDO A 707 |
| Chain | Residue |
| A | PRO656 |
| A | GLY657 |
| A | CA706 |
| B | ASP628 |
| B | THR658 |
| B | ASP659 |
| B | PHE679 |
| site_id | AC8 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 701 |
| Chain | Residue |
| B | SER471 |
| B | PHE472 |
| B | THR473 |
| B | TYR507 |
| B | EDO702 |
| B | HOH922 |
| C | HIS518 |
| site_id | AC9 |
| Number of Residues | 6 |
| Details | binding site for residue EDO B 702 |
| Chain | Residue |
| B | THR473 |
| B | TYR507 |
| B | EDO701 |
| B | HOH857 |
| D | HIS655 |
| D | PHE679 |
| site_id | AD1 |
| Number of Residues | 10 |
| Details | binding site for residue EDO B 703 |
| Chain | Residue |
| B | ALA476 |
| B | ALA477 |
| B | GLY479 |
| B | ALA480 |
| B | ASN481 |
| B | TYR482 |
| B | HOH813 |
| B | HOH977 |
| B | HOH985 |
| B | HOH1144 |
| site_id | AD2 |
| Number of Residues | 6 |
| Details | binding site for residue CA B 704 |
| Chain | Residue |
| B | PRO656 |
| B | EDO705 |
| C | ASP628 |
| C | ASP659 |
| C | GLY677 |
| C | HOH884 |
| site_id | AD3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO B 705 |
| Chain | Residue |
| B | PRO656 |
| B | GLY657 |
| B | CA704 |
| C | ASP628 |
| C | THR658 |
| C | ASP659 |
| C | PHE679 |
| site_id | AD4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 701 |
| Chain | Residue |
| C | ALA476 |
| C | ALA477 |
| C | GLY479 |
| C | ALA480 |
| C | ASN481 |
| C | TYR482 |
| C | HOH801 |
| C | HOH1028 |
| site_id | AD5 |
| Number of Residues | 8 |
| Details | binding site for residue EDO C 702 |
| Chain | Residue |
| A | PHE499 |
| A | HIS518 |
| C | SER471 |
| C | PHE472 |
| C | THR473 |
| C | TYR507 |
| C | HOH906 |
| C | HOH920 |
| site_id | AD6 |
| Number of Residues | 7 |
| Details | binding site for residue EDO C 703 |
| Chain | Residue |
| C | GLU510 |
| C | HIS530 |
| C | GLY532 |
| C | ASP533 |
| C | HOH839 |
| C | HOH1154 |
| A | ARG526 |
| site_id | AD7 |
| Number of Residues | 6 |
| Details | binding site for residue FE D 701 |
| Chain | Residue |
| D | HIS562 |
| D | HIS564 |
| E | HIS562 |
| E | HIS564 |
| F | HIS562 |
| F | HIS564 |
| site_id | AD8 |
| Number of Residues | 7 |
| Details | binding site for residue CA D 702 |
| Chain | Residue |
| D | ASP628 |
| D | GLY677 |
| D | HOH810 |
| D | HOH929 |
| D | HOH999 |
| F | PRO656 |
| F | HOH1112 |
| site_id | AD9 |
| Number of Residues | 5 |
| Details | binding site for residue EDO D 703 |
| Chain | Residue |
| D | THR361 |
| D | HOH914 |
| D | HOH928 |
| D | HOH972 |
| F | ASN458 |
| site_id | AE1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 704 |
| Chain | Residue |
| D | SER471 |
| D | PHE472 |
| D | THR473 |
| D | HOH807 |
| D | HOH854 |
| D | HOH1131 |
| E | HIS518 |
| site_id | AE2 |
| Number of Residues | 6 |
| Details | binding site for residue CA D 705 |
| Chain | Residue |
| D | PRO656 |
| D | EDO706 |
| E | ASP628 |
| E | ASP659 |
| E | GLY677 |
| E | HOH856 |
| site_id | AE3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO D 706 |
| Chain | Residue |
| D | PRO656 |
| D | GLY657 |
| D | CA705 |
| E | ASP628 |
| E | THR658 |
| E | ASP659 |
| E | PHE679 |
| site_id | AE4 |
| Number of Residues | 7 |
| Details | binding site for residue MG E 701 |
| Chain | Residue |
| D | HOH815 |
| D | HOH1029 |
| E | ASP613 |
| E | HOH839 |
| E | HOH1079 |
| F | HOH833 |
| F | HOH1006 |
| site_id | AE5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO E 702 |
| Chain | Residue |
| E | ASN365 |
| E | TYR390 |
| E | TYR412 |
| E | HOH903 |
| E | HOH1075 |
| E | HOH1103 |
| F | TYR398 |
| site_id | AE6 |
| Number of Residues | 4 |
| Details | binding site for residue EDO E 703 |
| Chain | Residue |
| E | SER471 |
| E | THR473 |
| E | TYR507 |
| E | HOH1108 |
| site_id | AE7 |
| Number of Residues | 9 |
| Details | binding site for residue EDO E 704 |
| Chain | Residue |
| E | ALA476 |
| E | ALA477 |
| E | GLY479 |
| E | ALA480 |
| E | ASN481 |
| E | TYR482 |
| E | HOH801 |
| E | HOH927 |
| E | HOH1021 |
| site_id | AE8 |
| Number of Residues | 8 |
| Details | binding site for residue EDO E 705 |
| Chain | Residue |
| A | HOH867 |
| B | ALA362 |
| E | ASP460 |
| E | VAL463 |
| E | ARG517 |
| E | TRP522 |
| E | HOH840 |
| E | HOH1227 |
| site_id | AE9 |
| Number of Residues | 6 |
| Details | binding site for residue CA E 706 |
| Chain | Residue |
| E | PRO656 |
| E | EDO707 |
| F | ASP628 |
| F | ASP659 |
| F | GLY677 |
| F | HOH810 |
| site_id | AF1 |
| Number of Residues | 7 |
| Details | binding site for residue EDO E 707 |
| Chain | Residue |
| E | PRO656 |
| E | GLY657 |
| E | CA706 |
| F | ASP628 |
| F | THR658 |
| F | ASP659 |
| F | PHE679 |
| site_id | AF2 |
| Number of Residues | 5 |
| Details | binding site for residue EDO F 701 |
| Chain | Residue |
| D | TYR398 |
| F | ASN365 |
| F | LEU378 |
| F | TYR390 |
| F | HOH873 |
| site_id | AF3 |
| Number of Residues | 7 |
| Details | binding site for residue EDO F 702 |
| Chain | Residue |
| F | ASP460 |
| F | VAL463 |
| F | ARG517 |
| F | TRP522 |
| F | HOH866 |
| F | HOH867 |
| F | HOH904 |
| site_id | AF4 |
| Number of Residues | 8 |
| Details | binding site for residue EDO F 703 |
| Chain | Residue |
| F | ALA476 |
| F | GLY479 |
| F | ALA480 |
| F | ASN481 |
| F | TYR482 |
| F | VAL485 |
| F | HOH999 |
| F | HOH1080 |
| site_id | AF5 |
| Number of Residues | 7 |
| Details | binding site for residue EDO F 704 |
| Chain | Residue |
| D | PHE499 |
| D | HIS518 |
| F | SER471 |
| F | PHE472 |
| F | THR473 |
| F | HOH842 |
| F | HOH951 |
