6CJB

Crystal structure of Cystathionine beta-lyase from Legionella pneumophila Philadelphia 1 covalently bound to Pyridoxal phosphate

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0000096	biological_process	sulfur amino acid metabolic process
A	0003962	molecular_function	cystathionine gamma-synthase activity
A	0004123	molecular_function	cystathionine gamma-lyase activity
A	0005737	cellular_component	cytoplasm
A	0016829	molecular_function	lyase activity
A	0016846	molecular_function	carbon-sulfur lyase activity
A	0019343	biological_process	cysteine biosynthetic process via cystathionine
A	0019346	biological_process	transsulfuration
A	0030170	molecular_function	pyridoxal phosphate binding
B	0000096	biological_process	sulfur amino acid metabolic process
B	0003962	molecular_function	cystathionine gamma-synthase activity
B	0004123	molecular_function	cystathionine gamma-lyase activity
B	0005737	cellular_component	cytoplasm
B	0016829	molecular_function	lyase activity
B	0016846	molecular_function	carbon-sulfur lyase activity
B	0019343	biological_process	cysteine biosynthetic process via cystathionine
B	0019346	biological_process	transsulfuration
B	0030170	molecular_function	pyridoxal phosphate binding
C	0000096	biological_process	sulfur amino acid metabolic process
C	0003962	molecular_function	cystathionine gamma-synthase activity
C	0004123	molecular_function	cystathionine gamma-lyase activity
C	0005737	cellular_component	cytoplasm
C	0016829	molecular_function	lyase activity
C	0016846	molecular_function	carbon-sulfur lyase activity
C	0019343	biological_process	cysteine biosynthetic process via cystathionine
C	0019346	biological_process	transsulfuration
C	0030170	molecular_function	pyridoxal phosphate binding
D	0000096	biological_process	sulfur amino acid metabolic process
D	0003962	molecular_function	cystathionine gamma-synthase activity
D	0004123	molecular_function	cystathionine gamma-lyase activity
D	0005737	cellular_component	cytoplasm
D	0016829	molecular_function	lyase activity
D	0016846	molecular_function	carbon-sulfur lyase activity
D	0019343	biological_process	cysteine biosynthetic process via cystathionine
D	0019346	biological_process	transsulfuration
D	0030170	molecular_function	pyridoxal phosphate binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	8
Details	binding site for residue FMT A 401

Chain	Residue
A	TYR101
A	ASN149
A	LLP199
A	SER328
A	LEU329
A	THR343
A	ARG363
A	HOH735

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site_id	AC2
Number of Residues	5
Details	binding site for residue FMT B 401

Chain	Residue
B	ASN149
B	SER328
B	THR343
B	ARG363
B	TYR101

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site_id	AC3
Number of Residues	8
Details	binding site for residue FMT C 401

Chain	Residue
C	TYR101
C	ASN149
C	LLP199
C	SER328
C	LEU329
C	THR343
C	ARG363
C	HOH700

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site_id	AC4
Number of Residues	7
Details	binding site for residue GOL C 402

Chain	Residue
C	GLU311
C	ASP312
C	ARG315
C	HOH571
C	HOH633
D	LYS273
D	ASP312

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site_id	AC5
Number of Residues	7
Details	binding site for residue FMT D 401

Chain	Residue
D	TYR101
D	ASN149
D	LLP199
D	SER328
D	LEU329
D	THR343
D	ARG363

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Functional Information from PROSITE/UniProt

site_id	PS00868
Number of Residues	15
Details	CYS_MET_METAB_PP Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. DIvlhSATKYLnGHS

Chain	Residue	Details
A	ASP191-SER205

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