6CJB
Crystal structure of Cystathionine beta-lyase from Legionella pneumophila Philadelphia 1 covalently bound to Pyridoxal phosphate
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003962 | molecular_function | cystathionine gamma-synthase activity |
| A | 0004123 | molecular_function | cystathionine gamma-lyase activity |
| A | 0005737 | cellular_component | cytoplasm |
| A | 0016846 | molecular_function | carbon-sulfur lyase activity |
| A | 0019346 | biological_process | transsulfuration |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 0003962 | molecular_function | cystathionine gamma-synthase activity |
| B | 0004123 | molecular_function | cystathionine gamma-lyase activity |
| B | 0005737 | cellular_component | cytoplasm |
| B | 0016846 | molecular_function | carbon-sulfur lyase activity |
| B | 0019346 | biological_process | transsulfuration |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| C | 0003962 | molecular_function | cystathionine gamma-synthase activity |
| C | 0004123 | molecular_function | cystathionine gamma-lyase activity |
| C | 0005737 | cellular_component | cytoplasm |
| C | 0016846 | molecular_function | carbon-sulfur lyase activity |
| C | 0019346 | biological_process | transsulfuration |
| C | 0030170 | molecular_function | pyridoxal phosphate binding |
| D | 0003962 | molecular_function | cystathionine gamma-synthase activity |
| D | 0004123 | molecular_function | cystathionine gamma-lyase activity |
| D | 0005737 | cellular_component | cytoplasm |
| D | 0016846 | molecular_function | carbon-sulfur lyase activity |
| D | 0019346 | biological_process | transsulfuration |
| D | 0030170 | molecular_function | pyridoxal phosphate binding |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 8 |
| Details | binding site for residue FMT A 401 |
| Chain | Residue |
| A | TYR101 |
| A | ASN149 |
| A | LLP199 |
| A | SER328 |
| A | LEU329 |
| A | THR343 |
| A | ARG363 |
| A | HOH735 |
| site_id | AC2 |
| Number of Residues | 5 |
| Details | binding site for residue FMT B 401 |
| Chain | Residue |
| B | ASN149 |
| B | SER328 |
| B | THR343 |
| B | ARG363 |
| B | TYR101 |
| site_id | AC3 |
| Number of Residues | 8 |
| Details | binding site for residue FMT C 401 |
| Chain | Residue |
| C | TYR101 |
| C | ASN149 |
| C | LLP199 |
| C | SER328 |
| C | LEU329 |
| C | THR343 |
| C | ARG363 |
| C | HOH700 |
| site_id | AC4 |
| Number of Residues | 7 |
| Details | binding site for residue GOL C 402 |
| Chain | Residue |
| C | GLU311 |
| C | ASP312 |
| C | ARG315 |
| C | HOH571 |
| C | HOH633 |
| D | LYS273 |
| D | ASP312 |
| site_id | AC5 |
| Number of Residues | 7 |
| Details | binding site for residue FMT D 401 |
| Chain | Residue |
| D | TYR101 |
| D | ASN149 |
| D | LLP199 |
| D | SER328 |
| D | LEU329 |
| D | THR343 |
| D | ARG363 |
Functional Information from PROSITE/UniProt
| site_id | PS00868 |
| Number of Residues | 15 |
| Details | CYS_MET_METAB_PP Cys/Met metabolism enzymes pyridoxal-phosphate attachment site. DIvlhSATKYLnGHS |
| Chain | Residue | Details |
| A | ASP191-SER205 |
