6CGQ
Threonine synthase from Bacillus subtilis ATCC 6633 with PLP and PLP-Ala
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0003941 | molecular_function | L-serine ammonia-lyase activity |
| A | 0004794 | molecular_function | threonine deaminase activity |
| A | 0004795 | molecular_function | threonine synthase activity |
| A | 0006520 | biological_process | amino acid metabolic process |
| A | 0006565 | biological_process | L-serine catabolic process |
| A | 0006567 | biological_process | L-threonine catabolic process |
| A | 0009088 | biological_process | L-threonine biosynthetic process |
| A | 0016829 | molecular_function | lyase activity |
| A | 0030170 | molecular_function | pyridoxal phosphate binding |
| A | 1901605 | biological_process | alpha-amino acid metabolic process |
| B | 0003941 | molecular_function | L-serine ammonia-lyase activity |
| B | 0004794 | molecular_function | threonine deaminase activity |
| B | 0004795 | molecular_function | threonine synthase activity |
| B | 0006520 | biological_process | amino acid metabolic process |
| B | 0006565 | biological_process | L-serine catabolic process |
| B | 0006567 | biological_process | L-threonine catabolic process |
| B | 0009088 | biological_process | L-threonine biosynthetic process |
| B | 0016829 | molecular_function | lyase activity |
| B | 0030170 | molecular_function | pyridoxal phosphate binding |
| B | 1901605 | biological_process | alpha-amino acid metabolic process |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 19 |
| Details | binding site for residue PLP A 401 |
| Chain | Residue |
| A | SER57 |
| A | ASN189 |
| A | ALA237 |
| A | ILE238 |
| A | GLU284 |
| A | THR314 |
| A | GLY315 |
| A | HOH518 |
| A | HOH589 |
| A | HOH591 |
| A | HOH598 |
| A | PHE58 |
| A | LYS59 |
| A | ASN85 |
| A | VAL184 |
| A | GLY185 |
| A | ASN186 |
| A | ALA187 |
| A | GLY188 |
| site_id | AC2 |
| Number of Residues | 8 |
| Details | binding site for residue PO4 B 401 |
| Chain | Residue |
| B | LYS59 |
| B | THR86 |
| B | ASN152 |
| B | SER153 |
| B | ARG158 |
| B | ASN186 |
| B | F0G402 |
| B | HOH562 |
| site_id | AC3 |
| Number of Residues | 24 |
| Details | binding site for residue F0G B 402 |
| Chain | Residue |
| B | PHE58 |
| B | LYS59 |
| B | SER82 |
| B | THR83 |
| B | GLY84 |
| B | ASN85 |
| B | THR86 |
| B | VAL184 |
| B | GLY185 |
| B | ASN186 |
| B | ALA187 |
| B | GLY188 |
| B | ASN189 |
| B | ALA237 |
| B | ILE238 |
| B | ILE240 |
| B | GLU284 |
| B | SER287 |
| B | THR314 |
| B | PO4401 |
| B | HOH510 |
| B | HOH531 |
| B | HOH542 |
| B | HOH562 |
Functional Information from PROSITE/UniProt
| site_id | PS00165 |
| Number of Residues | 14 |
| Details | DEHYDRATASE_SER_THR Serine/threonine dehydratases pyridoxal-phosphate attachment site. Egvnp.TGSFKDRGM |
| Chain | Residue | Details |
| A | GLU50-MET63 |
