Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000166 | molecular_function | nucleotide binding |
| A | 0003824 | molecular_function | catalytic activity |
| A | 0004748 | molecular_function | ribonucleoside-diphosphate reductase activity, thioredoxin disulfide as acceptor |
| A | 0005524 | molecular_function | ATP binding |
| A | 0005971 | cellular_component | ribonucleoside-diphosphate reductase complex |
| A | 0009263 | biological_process | deoxyribonucleotide biosynthetic process |
| A | 0016491 | molecular_function | oxidoreductase activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 12 |
| Details | binding site for residue D5M A 801 |
| Chain | Residue |
| A | VAL33 |
| A | ASP215 |
| A | PO4802 |
| A | HOH919 |
| A | HIS34 |
| A | PHE37 |
| A | ASN42 |
| A | ARG90 |
| A | PHE91 |
| A | ARG117 |
| A | ILE213 |
| A | LYS214 |
| site_id | AC2 |
| Number of Residues | 10 |
| Details | binding site for residue PO4 A 802 |
| Chain | Residue |
| A | LYS88 |
| A | ARG90 |
| A | ILE213 |
| A | LYS214 |
| A | ASP215 |
| A | GLU399 |
| A | GLU400 |
| A | ASP401 |
| A | D5M801 |
| A | HOH951 |
| site_id | AC3 |
| Number of Residues | 5 |
| Details | binding site for residue EDO A 803 |
| Chain | Residue |
| A | GLY476 |
| A | ALA478 |
| A | SER481 |
| A | GLU483 |
| A | LYS542 |
| site_id | AC4 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 804 |
| Chain | Residue |
| A | ARG350 |
| A | LEU656 |
| A | LEU667 |
| A | ASP671 |
| site_id | AC5 |
| Number of Residues | 4 |
| Details | binding site for residue EDO A 805 |
| Chain | Residue |
| A | GLU65 |
| A | GLU66 |
| A | GLU67 |
| A | LYS162 |
Functional Information from PROSITE/UniProt
| site_id | PS00089 |
| Number of Residues | 23 |
| Details | RIBORED_LARGE Ribonucleotide reductase large subunit signature. WkkLkafvaehGMYHsyrLCiaP |
| Chain | Residue | Details |
| A | TRP558-PRO580 | |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 2 |
| Details | Active site: {"description":"Proton acceptor","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI2 |
| Number of Residues | 1 |
| Details | Active site: {"description":"Cysteine radical intermediate","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI3 |
| Number of Residues | 11 |
| Details | Binding site: {"evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI4 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for hydrogen atom transfer","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI5 |
| Number of Residues | 2 |
| Details | Site: {"description":"Allosteric effector binding","evidences":[{"evidenceCode":"ECO:0000250"}]} |
| site_id | SWS_FT_FI6 |
| Number of Residues | 2 |
| Details | Site: {"description":"Important for electron transfer","evidences":[{"evidenceCode":"ECO:0000250"}]} |
