6CF1
Proteus vulgaris HigA antitoxin structure
Functional Information from GO Data
| Chain | GOid | namespace | contents |
| A | 0000976 | molecular_function | transcription cis-regulatory region binding |
| A | 0003677 | molecular_function | DNA binding |
| A | 0003700 | molecular_function | DNA-binding transcription factor activity |
| A | 0005515 | molecular_function | protein binding |
| A | 0006355 | biological_process | regulation of DNA-templated transcription |
| A | 0046982 | molecular_function | protein heterodimerization activity |
| A | 0097351 | molecular_function | toxin sequestering activity |
| B | 0000976 | molecular_function | transcription cis-regulatory region binding |
| B | 0003677 | molecular_function | DNA binding |
| B | 0003700 | molecular_function | DNA-binding transcription factor activity |
| B | 0005515 | molecular_function | protein binding |
| B | 0006355 | biological_process | regulation of DNA-templated transcription |
| B | 0046982 | molecular_function | protein heterodimerization activity |
| B | 0097351 | molecular_function | toxin sequestering activity |
Functional Information from PDB Data
| site_id | AC1 |
| Number of Residues | 4 |
| Details | binding site for residue K A 201 |
| Chain | Residue |
| A | ASP19 |
| A | HOH363 |
| B | GLU65 |
| B | HOH352 |
| site_id | AC2 |
| Number of Residues | 4 |
| Details | binding site for residue K A 202 |
| Chain | Residue |
| A | GLU65 |
| A | GLU93 |
| B | HIS29 |
| B | GLU80 |
| site_id | AC3 |
| Number of Residues | 4 |
| Details | binding site for residue K A 203 |
| Chain | Residue |
| A | ASP16 |
| A | MET20 |
| A | HOH311 |
| A | GLN3 |
| site_id | AC4 |
| Number of Residues | 3 |
| Details | binding site for residue K A 204 |
| Chain | Residue |
| A | HIS29 |
| A | HOH362 |
| B | HOH363 |
| site_id | AC5 |
| Number of Residues | 2 |
| Details | binding site for residue K B 201 |
| Chain | Residue |
| B | ASP16 |
| B | HOH354 |
Functional Information from SwissProt/UniProt
| site_id | SWS_FT_FI1 |
| Number of Residues | 38 |
| Details | DNA_BIND: H-T-H motif => ECO:0000255|PROSITE-ProRule:PRU00257, ECO:0007744|PDB:4MCT, ECO:0007744|PDB:4MCX |
| Chain | Residue | Details |
| A | GLY24-ALA43 | |
| B | GLY24-ALA43 |
| site_id | SWS_FT_FI2 |
| Number of Residues | 4 |
| Details | SITE: Interaction with HigB => ECO:0000269|PubMed:24257752 |
| Chain | Residue | Details |
| A | GLN3 | |
| A | PHE4 | |
| B | GLN3 | |
| B | PHE4 |
