6CEA

Crystal structure of fragment 3-(quinolin-2-yl)propanoic acid bound in the ubiquitin binding pocket of the HDAC6 zinc-finger domain

Functional Information from GO Data

Chain	GOid	namespace	contents
A	0008270	molecular_function	zinc ion binding

Functional Information from PDB Data

site_id	AC1
Number of Residues	4
Details	binding site for residue ZN A 1301

Chain	Residue
A	CYS1145
A	CYS1148
A	HIS1164
A	HIS1170

---

site_id	AC2
Number of Residues	4
Details	binding site for residue ZN A 1302

Chain	Residue
A	CYS1133
A	CYS1136
A	CYS1153
A	HIS1160

---

site_id	AC3
Number of Residues	4
Details	binding site for residue ZN A 1303

Chain	Residue
A	HIS1115
A	CYS1183
A	CYS1186
A	CYS1113

---

site_id	AC4
Number of Residues	7
Details	binding site for residue EYY A 1305

Chain	Residue
A	TRP1143
A	GLY1154
A	ARG1155
A	TRP1182
A	TYR1184
A	TYR1189
A	HOH1408

---

Functional Information from SwissProt/UniProt

site_id	SWS_FT_FI1
Number of Residues	98
Details	ZN_FING: UBP-type => ECO:0000255|PROSITE-ProRule:PRU00502

Chain	Residue	Details
A	PRO1111-GLU1209

---

site_id	SWS_FT_FI2
Number of Residues	12
Details	BINDING: BINDING => ECO:0000255|PROSITE-ProRule:PRU00502, ECO:0000269|Ref.35, ECO:0000269|Ref.36

Chain	Residue	Details
A	CYS1145
A	CYS1148
A	CYS1153
A	HIS1160
A	HIS1164
A	HIS1170
A	CYS1183
A	CYS1186
A	CYS1113
A	HIS1115
A	CYS1133
A	CYS1136

---