Functional Information from GO Data
Chain | GOid | namespace | contents |
A | 0004190 | molecular_function | aspartic-type endopeptidase activity |
A | 0006508 | biological_process | proteolysis |
B | 0004190 | molecular_function | aspartic-type endopeptidase activity |
B | 0006508 | biological_process | proteolysis |
Functional Information from PDB Data
site_id | AC1 |
Number of Residues | 6 |
Details | binding site for residue NA A 501 |
Chain | Residue |
A | ASP60 |
A | HOH614 |
A | HOH628 |
A | HOH646 |
A | HOH667 |
A | HOH668 |
site_id | AC2 |
Number of Residues | 3 |
Details | binding site for residue CL A 502 |
Chain | Residue |
A | THR74 |
A | ASN88 |
B | ARG41 |
site_id | AC3 |
Number of Residues | 9 |
Details | binding site for residue GOL A 503 |
Chain | Residue |
A | LYS45 |
A | MET46 |
A | PHE53 |
A | HOH605 |
A | HOH618 |
A | HOH673 |
B | GLY73 |
B | GLN92 |
B | HOH332 |
site_id | AC4 |
Number of Residues | 31 |
Details | binding site for residue GR5 B 201 |
Chain | Residue |
A | ARG8 |
A | ASP25 |
A | GLY27 |
A | ALA28 |
A | ASP29 |
A | ASP30 |
A | ILE47 |
A | GLY48 |
A | GLY49 |
A | ILE50 |
A | PRO81 |
A | VAL82 |
A | ILE84 |
A | HOH618 |
A | HOH625 |
A | HOH640 |
B | ARG8 |
B | ASP25 |
B | GLY27 |
B | ALA28 |
B | ASP29 |
B | ASP30 |
B | GLY48 |
B | GLY49 |
B | ILE50 |
B | PRO81 |
B | VAL82 |
B | ILE84 |
B | HOH302 |
B | HOH352 |
B | HOH377 |
site_id | AC5 |
Number of Residues | 2 |
Details | binding site for residue CL B 202 |
site_id | AC6 |
Number of Residues | 7 |
Details | binding site for residue ACT B 203 |
Chain | Residue |
B | PRO39 |
B | ARG41 |
B | TYR59 |
B | ASP60 |
B | HOH333 |
B | HOH342 |
B | HOH375 |
site_id | AC7 |
Number of Residues | 7 |
Details | binding site for residue GOL B 204 |
Chain | Residue |
A | GLN18 |
A | MET36 |
A | SER37 |
B | THR12 |
B | GLU65 |
B | ALA67 |
B | GLY68 |
Functional Information from PROSITE/UniProt
site_id | PS00141 |
Number of Residues | 12 |
Details | ASP_PROTEASE Eukaryotic and viral aspartyl proteases active site. ALLDTGADDTVI |
Chain | Residue | Details |
A | ALA22-ILE33 | |